Supercritical Carbon Dioxide Extraction of Andrographolide from Andrographis paniculata: Effect of the Solvent Flow Rate, Pressure, and Temperature* * Supported by the Intensification of Research in Priority Areas Project (IRPA), Ministry of Science, Technology and Innovation, Malaysia (No.09-02-03-0101-EA0001).

Chinese Journal of Chemical Engineering

Volumn 15, Issue 6, 2007, Pages 877-883

  Kumoro, A C ^a   Hasan, Masitah ^b  

^a DIPONEGORO UNIVERSITY   (Indonesia)

^b UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Andrographis paniculata; andrographolide; extraction; supercritical carbon dioxide

Indexed keywords

CARBON DIOXIDE; FLAMMABILITY; FLOW RATE; SUPERCRITICAL FLUID EXTRACTION;

ANDROGRAPHIS PANICULATA; ANDROGRAPHOLIDE; SUPERCRITICAL CARBON DIOXIDE;

PLANTS (BOTANY);

CARBON DIOXIDE; FLAMMABILITY; FLOW RATE; PLANTS (BOTANY); SUPERCRITICAL FLUID EXTRACTION;

EID: 38049027694     PISSN: 10049541     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1004-9541(08)60018-X     Document Type: Article

References (31)

1. Wongkittipong R., Prat L., Damronglerd S., and Gourdon C. "Solid-liquid extraction of andrographolide from plants-experimental study, kinetic reaction and model". Sep. Purif. Technol. 40 (2000) 147-154
2. Calabrese C., Berman S.H., and Babish J.G. "A phase I trial of andrographolide in HIV positive patients and normal volunteers". Phytother. Res. 14 (2000) 333-338
3. Choudhury B.R., Haque S.J., and Poddar M.K. "In vivo and in vitro effects of kalmegh (Andrographis paniculata) extract and andrographolide on hepatic microsomal drug metabolising enzymes". Planta Med. 53 (1987) 135-140
4. Rajani M., Shrivastava N., and Ravishankara M.N. "A rapid method for isolation of andrographolide from Andrographis paniculata Nees (Kalmegh)". Pharmaceut. Biol. 38 (2000) 204-209
5. 2 extraction of nimbin from neem seeds--An experimental study". J. Food Eng. 47 (2001) 289-293
6. Jarvis A.P., and Morgan E.D. "Isolation of plant products by supercritical-fluid extraction". Phytochem. Anal. 8 (1997) 217-222
7. 2 extraction of essential oils and cuticular waxes from peppermint leaves". J. Chem.Technol. Biotechnol. 67 (1996) 21-26
8. Ge F.H., Lin X.X., Huan X.F., Shi Q., Liang B., Li J., and Zhong G. "Study on extraction of active ingredients from Andrographis paniculata using orthogonal experiment with supercritical carbon dioxids". J. Chinese Med. Mater. 25 2 (2002) 101-102 (in Chinese)
9. Elkanzi E.M., and Singh H. "Extraction of used lubricating oils with supercritical carbon dioxide". Arabian J. Sci. Eng. 26 2C (2001) 11-23
10. 2-methanol mixture". J. Supercrit. Fluids 30 (2004) 287-301
11. 2". J. Supercrit. Fluids 22 (2002) 119-127
12. Macnaughton S.J., and Foster N.R. "Supercritical adsorption and desorption behaviour of DDT on activated carbon using carbon dioxide". Ind. Eng. Chem. Res. 34 (1995) 275-282
13. Goto M., Sato M., and Hirose T. "Extraction of peppermint oil by supercritical carbon dioxide". J. Chem. Eng. Japan 26 4 (1993) 401-407
14. Goto M., Roy B.C., Kodama A., and Hirose T. "Modelling supercritical fluid extraction process involving solute-solid interaction". J. Chem. Eng. Japan 31 2 (1998) 171-177
15. Vetere A. "A short-cut method to predict the solubilities of solids in supercritical carbon dioxide". Fluid Phase Equil. 148 (1998) 83-93
16. 2 adsorption on activated carbon: Effect of operating conditions and adsorption scale-up". J. Supercrit. Fluids 32 (2004) 193-201
17. 2 in packed bed extractor". J. Supercrit. Fluids 28 (2004) 11-19
18. Marentis R.T. "Steps to developing a commercial supercritical carbon dioxide processing plant". In: Carpentier B.A., and Sevenants M.R. (Eds). Supercritical Fluid Extraction Chromatography (1988), American Chemical Society, Washington, DC
19. Roy B.C., Goto M., and Hirose T. "Extraction of ginger oil with supercritical carbon dioxide: experiments and modeling". Ind. Eng. Chem. Res. 35 (1996) 607-612
20. Span R., and Wagner W. "A new equation of state carbon dioxide covering the region from triple-point temperature to 1100K at pressure up to 800MPa.". J. Phys. Chem. Ref. Data 25 6 (1996) 1509-1596
21. Jossi J.A., Stiel L.I., and Thodos G. "The viscosity of pure substances in the dense gaseous and liquid phases". AIChE J. 8 1 (1962) 59-62
22. Liu H., Silva C.M., and Macedo E.A. "Unified approach to the self-diffusion coefficients of dense fluids over wide ranges of temperature and pressure-hard-sphere, square-well, Lennard-Jones and real substances". Chem. Eng. Sci. 53 13 (1998) 2403-2422
23. Baysal T., and Starmans D.A.J. "Supercritical carbon dioxide extraction of carvone and limonene from caraway seed". J. Supercrit. Fluids 14 (1999) 225-234
24. de Franca L.F., Reber G., Meireles M.A.A., Machado N.T., and Brunner G. "Supercritical extraction of carotenoids and lipids from buriti (Mauritia flexuosa), a fruit from the Amazon region". J. Supercrit.Fluids 14 (1999) 247-256
25. D'Andrea, A., Ferri, D., Maccioni, O., van der Esch, S.A., Vitali, F., "Application of SFE technology to the extraction of active substances from Azadirachta indica (A. juss) seeds", Kleeburg, H., eds., In: Practice Oriented Results on the Use and Production of Neem Ingredients and Pheromones", Drug und Graphic, Giessen (1994).
26. Brunner G., Birtich A., and Johannsen M. "Supercritical fluid extraction of oil-palm components". J. Supercrit. Fluids 8 (1995) 46-50
27. de Lucas A., de la Ossa E.M., Rincón J., Blanco M.A., and Gracia I. "Supercritical fluid extraction of tocopherol concentrates from olive tree leaves". J. Supercrit. Fluids 22 (2002) 221-228
28. 2 extraction efficiencies of polycyclic aromatic hydrocarbons from environmental samples". Anal. Chem. 67 3 (1995) 641-646
29. Kiriamiti H.K., Rascol E., Marty A., and Condoret J.S. "Extraction rates of oil from high oleic sunflower seeds with supercritical carbon dioxide". Chem. Eng. Process. 41 (2002) 711-718
30. Vetere A. "A short-cut method to predict the solubilities of solids in supercritical carbon dioxide". Fluid Phase Equilib. 148 (1998) 83-93
31. Skerget M., and Knez Z. "Modelling high pressure extraction processes". Comp. Chem. Eng. 25 (2001) 879-886