메뉴 건너뛰기




Volumn 30, Issue 1-2, 2008, Pages 21-28

In vitro induction of regulatory T cells by anti-CD3 antibody in humans

Author keywords

Anti CD3; Autoimmunity; Regulatory T cells

Indexed keywords

CD3 ANTIBODY; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; MONOCLONAL ANTIBODY CD28; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 38049007455     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2007.11.007     Document Type: Article
Times cited : (45)

References (38)
  • 2
    • 0037182839 scopus 로고    scopus 로고
    • OKT3 (muromonab-CD3) associated hepatitis in a kidney transplant recipient
    • Go M.R., and Bumgardner G.L. OKT3 (muromonab-CD3) associated hepatitis in a kidney transplant recipient. Transplantation 73 (2002) 1957
    • (2002) Transplantation , vol.73 , pp. 1957
    • Go, M.R.1    Bumgardner, G.L.2
  • 3
    • 0141796312 scopus 로고    scopus 로고
    • TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
    • Belghith M., Bluestone J.A., Barriot S., Megret J., Bach J.F., and Chatenoud L. TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 9 (2003) 1202
    • (2003) Nat Med , vol.9 , pp. 1202
    • Belghith, M.1    Bluestone, J.A.2    Barriot, S.3    Megret, J.4    Bach, J.F.5    Chatenoud, L.6
  • 4
    • 0034802139 scopus 로고    scopus 로고
    • Reversal of experimental allergic encephalomyelitis with non-mitogenic, non-depleting anti-CD3 mAb therapy with a preferential effect on T(h)1 cells that is augmented by IL-4
    • Tran G.T., Carter N., He X.Y., Spicer T.S., Plain K.M., Nicolls M., et al. Reversal of experimental allergic encephalomyelitis with non-mitogenic, non-depleting anti-CD3 mAb therapy with a preferential effect on T(h)1 cells that is augmented by IL-4. Int Immunol 13 (2001) 1109
    • (2001) Int Immunol , vol.13 , pp. 1109
    • Tran, G.T.1    Carter, N.2    He, X.Y.3    Spicer, T.S.4    Plain, K.M.5    Nicolls, M.6
  • 5
    • 17044425656 scopus 로고    scopus 로고
    • Treatment with nonmitogenic anti-CD3 monoclonal antibody induces CD4 + T cell unresponsiveness and functional reversal of established experimental autoimmune encephalomyelitis
    • Kohm A.P., Williams J.S., Bickford A.L., McMahon J.S., Chatenoud L., Bach J.F., et al. Treatment with nonmitogenic anti-CD3 monoclonal antibody induces CD4 + T cell unresponsiveness and functional reversal of established experimental autoimmune encephalomyelitis. J Immunol 174 (2005) 4525
    • (2005) J Immunol , vol.174 , pp. 4525
    • Kohm, A.P.1    Williams, J.S.2    Bickford, A.L.3    McMahon, J.S.4    Chatenoud, L.5    Bach, J.F.6
  • 6
    • 0028027876 scopus 로고
    • A randomized trial of OKT3-based versus cyclosporine-based immunoprophylaxis after liver transplantation. Long-term results of a European and Australian multicenter study
    • Farges O., Ericzon B.G., Bresson-Hadni S., Lynch S.V., Hockerstedt K., Houssin D., et al. A randomized trial of OKT3-based versus cyclosporine-based immunoprophylaxis after liver transplantation. Long-term results of a European and Australian multicenter study. Transplantation 58 (1994) 891
    • (1994) Transplantation , vol.58 , pp. 891
    • Farges, O.1    Ericzon, B.G.2    Bresson-Hadni, S.3    Lynch, S.V.4    Hockerstedt, K.5    Houssin, D.6
  • 8
    • 0036774891 scopus 로고    scopus 로고
    • Immunotherapy of insulin-dependent diabetes mellitus
    • Masteller E.L., and Bluestone J.A. Immunotherapy of insulin-dependent diabetes mellitus. Curr Opin Immunol 14 (2002) 652
    • (2002) Curr Opin Immunol , vol.14 , pp. 652
    • Masteller, E.L.1    Bluestone, J.A.2
  • 11
    • 33947726341 scopus 로고    scopus 로고
    • Moving towards efficient therapies in type 1 diabetes: to combine or not to combine?
    • Bresson D., and von Herrath M. Moving towards efficient therapies in type 1 diabetes: to combine or not to combine?. Autoimmun Rev 6 (2007) 315
    • (2007) Autoimmun Rev , vol.6 , pp. 315
    • Bresson, D.1    von Herrath, M.2
  • 12
    • 0036733642 scopus 로고    scopus 로고
    • Modified anti-CD3 therapy in psoriatic arthritis: a phase I/II clinical trial
    • Utset T.O., Auger J.A., Peace D., Zivin R.A., Xu D., Jolliffe L., et al. Modified anti-CD3 therapy in psoriatic arthritis: a phase I/II clinical trial. J Rheumatol 29 (2002) 1907
    • (2002) J Rheumatol , vol.29 , pp. 1907
    • Utset, T.O.1    Auger, J.A.2    Peace, D.3    Zivin, R.A.4    Xu, D.5    Jolliffe, L.6
  • 13
    • 0036023129 scopus 로고    scopus 로고
    • Remission and pancreas isograft survival in recent onset diabetic NOD mice after treatment with low-dose anti-CD3 monoclonal antibodies
    • Mottram P.L., Murray-Segal L.J., Han W., Maguire J., and Stein-Oakley A.N. Remission and pancreas isograft survival in recent onset diabetic NOD mice after treatment with low-dose anti-CD3 monoclonal antibodies. Transpl Immunol 10 (2002) 63
    • (2002) Transpl Immunol , vol.10 , pp. 63
    • Mottram, P.L.1    Murray-Segal, L.J.2    Han, W.3    Maguire, J.4    Stein-Oakley, A.N.5
  • 14
    • 0027315279 scopus 로고
    • Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells
    • Wesselborg S., Janssen O., and Kabelitz D. Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells. J Immunol 150 (1993) 4338
    • (1993) J Immunol , vol.150 , pp. 4338
    • Wesselborg, S.1    Janssen, O.2    Kabelitz, D.3
  • 15
    • 0026528912 scopus 로고
    • Immunosuppression by OKT3-induction of programmed cell death (apoptosis) as a possible mechanism of action
    • Janssen O., Wesselborg S., and Kabelitz D. Immunosuppression by OKT3-induction of programmed cell death (apoptosis) as a possible mechanism of action. Transplantation 53 (1992) 233
    • (1992) Transplantation , vol.53 , pp. 233
    • Janssen, O.1    Wesselborg, S.2    Kabelitz, D.3
  • 16
    • 0026088887 scopus 로고
    • Selective reduction and proliferation of the CD4+ and CD8+ T cell subsets with bispecific monoclonal antibodies: evidence for inter-T cell-mediated cytolysis
    • Wong J.T., and Colvin R.B. Selective reduction and proliferation of the CD4+ and CD8+ T cell subsets with bispecific monoclonal antibodies: evidence for inter-T cell-mediated cytolysis. Clin Immunol Immunopathol 58 (1991) 236
    • (1991) Clin Immunol Immunopathol , vol.58 , pp. 236
    • Wong, J.T.1    Colvin, R.B.2
  • 17
    • 0023219897 scopus 로고
    • Induction of cytotoxicity in human peripheral blood mononuclear cells by monoclonal antibody OKT3
    • Jung G., Martin D.E., and Muller-Eberhard H.J. Induction of cytotoxicity in human peripheral blood mononuclear cells by monoclonal antibody OKT3. J Immunol 139 (1987) 639
    • (1987) J Immunol , vol.139 , pp. 639
    • Jung, G.1    Martin, D.E.2    Muller-Eberhard, H.J.3
  • 18
    • 33746973702 scopus 로고    scopus 로고
    • Transforming growth factor-beta: an important role in CD4+ CD25+ regulatory T cells and immune tolerance
    • Zhang L., Yi H., Xia X.P., and Zhao Y. Transforming growth factor-beta: an important role in CD4+ CD25+ regulatory T cells and immune tolerance. Autoimmunity 39 (2006) 269
    • (2006) Autoimmunity , vol.39 , pp. 269
    • Zhang, L.1    Yi, H.2    Xia, X.P.3    Zhao, Y.4
  • 19
    • 33744990181 scopus 로고    scopus 로고
    • Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25- LAP+ T cells
    • Ochi H., Abraham M., Ishikawa H., Frenkel D., Yang K., Basso A.S., et al. Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25- LAP+ T cells. Nat Med 12 (2006) 627
    • (2006) Nat Med , vol.12 , pp. 627
    • Ochi, H.1    Abraham, M.2    Ishikawa, H.3    Frenkel, D.4    Yang, K.5    Basso, A.S.6
  • 20
    • 0031647622 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25+ CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state
    • Takahashi T., Kuniyasu Y., Toda M., Sakaguchi N., Itoh M., Iwata M., et al. Immunologic self-tolerance maintained by CD25+ CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol 10 (1998) 1969
    • (1998) Int Immunol , vol.10 , pp. 1969
    • Takahashi, T.1    Kuniyasu, Y.2    Toda, M.3    Sakaguchi, N.4    Itoh, M.5    Iwata, M.6
  • 21
    • 33746581243 scopus 로고    scopus 로고
    • FoxP3: a genetic link between immunodeficiency and autoimmune diseases
    • Chang X., Zheng P., and Liu Y. FoxP3: a genetic link between immunodeficiency and autoimmune diseases. Autoimmun Rev 5 (2006) 399
    • (2006) Autoimmun Rev , vol.5 , pp. 399
    • Chang, X.1    Zheng, P.2    Liu, Y.3
  • 22
    • 27144483896 scopus 로고    scopus 로고
    • CD3-specific antibodies restore self-tolerance: mechanisms and clinical applications
    • Chatenoud L. CD3-specific antibodies restore self-tolerance: mechanisms and clinical applications. Curr Opin Immunol 17 (2005) 632
    • (2005) Curr Opin Immunol , vol.17 , pp. 632
    • Chatenoud, L.1
  • 23
    • 33744536222 scopus 로고    scopus 로고
    • Lineage and signal strength determine the inhibitory effect of transforming growth factor beta1 (TGF-beta1) on human antigen-specific Th1 and Th2 memory cells
    • Holzer U., Rieck M., and Buckner J.H. Lineage and signal strength determine the inhibitory effect of transforming growth factor beta1 (TGF-beta1) on human antigen-specific Th1 and Th2 memory cells. J Autoimmun 26 (2006) 241
    • (2006) J Autoimmun , vol.26 , pp. 241
    • Holzer, U.1    Rieck, M.2    Buckner, J.H.3
  • 24
  • 25
    • 0036467410 scopus 로고    scopus 로고
    • Human anergic CD4+ T cells can act as suppressor cells by affecting autologous dendritic cell conditioning and survival
    • Frasca L., Scotta C., Lombardi G., and Piccolella E. Human anergic CD4+ T cells can act as suppressor cells by affecting autologous dendritic cell conditioning and survival. J Immunol 168 (2002) 1060
    • (2002) J Immunol , vol.168 , pp. 1060
    • Frasca, L.1    Scotta, C.2    Lombardi, G.3    Piccolella, E.4
  • 26
    • 28444434811 scopus 로고    scopus 로고
    • IPEX and FOXP3: clinical and research perspectives
    • Wildin R.S., and Freitas A. IPEX and FOXP3: clinical and research perspectives. J Autoimmun 25 Suppl (2005) 56
    • (2005) J Autoimmun , vol.25 , Issue.SUPPL , pp. 56
    • Wildin, R.S.1    Freitas, A.2
  • 27
    • 26244448037 scopus 로고    scopus 로고
    • CD4+ regulatory T cells: mechanisms of induction and effector function
    • Bacchetta R., Gregori S., and Roncarolo M.G. CD4+ regulatory T cells: mechanisms of induction and effector function. Autoimmun Rev 4 (2005) 491
    • (2005) Autoimmun Rev , vol.4 , pp. 491
    • Bacchetta, R.1    Gregori, S.2    Roncarolo, M.G.3
  • 28
    • 38049072128 scopus 로고    scopus 로고
    • Antinucleosome antibodies in primary antiphospholipid syndrome: a hint at systemic autoimmunity
    • Andreoli L., Pregnolato F., Burlingame R., Allegri F., Rizzini S., Fanelli V., et al. Antinucleosome antibodies in primary antiphospholipid syndrome: a hint at systemic autoimmunity. J Autoimmun 30 (2008) 84-89
    • (2008) J Autoimmun , vol.30 , pp. 84-89
    • Andreoli, L.1    Pregnolato, F.2    Burlingame, R.3    Allegri, F.4    Rizzini, S.5    Fanelli, V.6
  • 29
    • 38049072128 scopus 로고    scopus 로고
    • Antinucleosome antibodies in primary antiphospholipid syndrome: a hint at systemic autoimmunity
    • Andreoli L., Pregnolato F., Burlingame R., Allegri F., Rizzini S., Fanelli V., et al. Antinucleosome antibodies in primary antiphospholipid syndrome: a hint at systemic autoimmunity. J Autoimmun 30 (2008) 51-57
    • (2008) J Autoimmun , vol.30 , pp. 51-57
    • Andreoli, L.1    Pregnolato, F.2    Burlingame, R.3    Allegri, F.4    Rizzini, S.5    Fanelli, V.6
  • 30
    • 38049065080 scopus 로고    scopus 로고
    • Does the BAFF dysregulation play a major role in the pathogenesis of systemic lupus erythematosus?
    • Binard A., Le Pottier L., Saraux A., Devauchelle-Pensec V., Pers J.-O., and Youinou P. Does the BAFF dysregulation play a major role in the pathogenesis of systemic lupus erythematosus?. J Autoimmun 30 (2008) 63-67
    • (2008) J Autoimmun , vol.30 , pp. 63-67
    • Binard, A.1    Le Pottier, L.2    Saraux, A.3    Devauchelle-Pensec, V.4    Pers, J.-O.5    Youinou, P.6
  • 31
    • 38049068750 scopus 로고    scopus 로고
    • The HLA gene complex in thyroid autoimmunity: from epidemiology to etiology
    • Jacobson E., Huber A., and Tomer Y. The HLA gene complex in thyroid autoimmunity: from epidemiology to etiology. J Autoimmun 30 (2008) 58-63
    • (2008) J Autoimmun , vol.30 , pp. 58-63
    • Jacobson, E.1    Huber, A.2    Tomer, Y.3
  • 32
    • 38049051222 scopus 로고    scopus 로고
    • Pathogenesis of PR3-ANCA associated vasculitis
    • Kallenberg C. Pathogenesis of PR3-ANCA associated vasculitis. J Autoimmun 30 (2008) 29-36
    • (2008) J Autoimmun , vol.30 , pp. 29-36
    • Kallenberg, C.1
  • 33
    • 38049078520 scopus 로고    scopus 로고
    • Cell damage and autoimmunity: a critical appraisal
    • Mackay I., Leskovek N., and Rose N. Cell damage and autoimmunity: a critical appraisal. J Autoimmun 30 (2008) 5-11
    • (2008) J Autoimmun , vol.30 , pp. 5-11
    • Mackay, I.1    Leskovek, N.2    Rose, N.3
  • 34
    • 38049028313 scopus 로고    scopus 로고
    • Monosodium glutamate (MSG): a villain and promoter of liver inflammation and dysplasia
    • Nakanishi Y., Tsuneyama K., Fujimoto M., Thucydides L., Nomoto K., An J.-L., et al. Monosodium glutamate (MSG): a villain and promoter of liver inflammation and dysplasia. J Autoimmun 30 (2008) 42-50
    • (2008) J Autoimmun , vol.30 , pp. 42-50
    • Nakanishi, Y.1    Tsuneyama, K.2    Fujimoto, M.3    Thucydides, L.4    Nomoto, K.5    An, J.-L.6
  • 35
    • 38049031900 scopus 로고    scopus 로고
    • Integrating immunity: the immunculus and self reactivity
    • Poletaev A., Stepanyuk V., and Gershwin M. Integrating immunity: the immunculus and self reactivity. J Autoimmun 2008 30 (2007) 68-73
    • (2007) J Autoimmun , vol.2008 , Issue.30 , pp. 68-73
    • Poletaev, A.1    Stepanyuk, V.2    Gershwin, M.3
  • 36
    • 38049036446 scopus 로고    scopus 로고
    • The curiously suspicious: infectious disease may ameliorate an ongoing autoimmune destruction in systemic lupus erythematosus patients
    • Praprotnik S., Snezna S.-S., Tomsic M., and Shoenfeld Y. The curiously suspicious: infectious disease may ameliorate an ongoing autoimmune destruction in systemic lupus erythematosus patients. J Autoimmun 30 (2008) 37-41
    • (2008) J Autoimmun , vol.30 , pp. 37-41
    • Praprotnik, S.1    Snezna, S.-S.2    Tomsic, M.3    Shoenfeld, Y.4
  • 38
    • 38049050759 scopus 로고    scopus 로고
    • Autoimmunity: from the mosaic to the kaleidoscope
    • Shoenfeld Y., and Gershwin M. Autoimmunity: from the mosaic to the kaleidoscope. J Autoimmun 30 (2008) 1-4
    • (2008) J Autoimmun , vol.30 , pp. 1-4
    • Shoenfeld, Y.1    Gershwin, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.