Impulsivity, Compulsivity, and Habit: The Role of Orbitofrontal Cortex Revisited

Biological Psychiatry

Volumn 63, Issue 3, 2008, Pages 253-255

  Torregrossa, Mary M ^a   Quinn, Jennifer J ^a   Taylor, Jane R ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ATTENTION DEFICIT DISORDER; BEHAVIOR; BRAIN FUNCTION; COGNITION; COMPULSION; DRUG DEPENDENCE; GILLES DE LA TOURETTE SYNDROME; HABIT; HUMAN; IMPULSIVENESS; MENTAL DISEASE; NONHUMAN; OBSESSIVE COMPULSIVE DISORDER; ORBITAL CORTEX; PREFRONTAL CORTEX; PRIORITY JOURNAL; STIMULUS RESPONSE; TASK PERFORMANCE;

EID: 37849026950     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2007.11.014     Document Type: Note

References (44)

1. Haas L.F. Phineas Gage and the science of brain localization. J Neurol Neurosurg Psychiatry 71 (2001) 761
2. Murray E.A., O'Doherty J.P., and Schoenbaum G. What we know and do not know about the functions of the orbitofrontal cortex after 20 years of cross-species studies. J Neurosci 27 (2007) 8166-8169
3. Berlin H.A., Rolls E.T., and Kischka U. Impulsivity, time perception, emotion and reinforcement sensitivity in patients with orbitofrontal cortex lesions. Brain 127 (2004) 1108-1126
4. Chamberlain S.R., and Sahakian B.J. The neuropsychiatry of impulsivity. Curr Opin Psychiatry 20 (2007) 255-261
5. Jentsch J.D., and Taylor J.R. Impulsivity resulting from frontostriatal dysfunction in drug abuse: Implications for the control of behavior by reward-related stimuli. Psychopharmacol 146 (1999) 373-390
6. Roberts A.C., and Wallis J.D. Inhibitory control and affective processing in the prefrontal cortex: Neuropsychological studies in the common marmoset. Cereb Cortex 10 (2000) 252-262
7. Hildebrandt H., Brokate B., Hoffmann E., Kroger B., and Eling P. Conditional responding is impaired in chronic alcoholics. J Clin Exp Neuropsychol 28 (2006) 631-645
8. Bechara A. Risky business: Emotion, decision-making, and addiction. J Gambl Stud 19 (2003) 23-51
9. Schoenbaum G., Roesch M.R., and Stalnaker T.A. Orbitofrontal cortex, decision-making and drug addiction. Trends Neurosci 29 (2006) 116-124
10. Rogers R.D., Everitt B.J., Baldacchino A., Blackshaw A.J., Swainson R., Wynne K., et al. Dissociable deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depleted normal volunteers: Evidence for monoaminergic mechanisms. Neuropsychopharmacol 20 (1999) 322-339
11. Sheppard D.M., Bradshaw J.L., Purcell R., and Pantelis C. Tourette's and comorbid syndromes: Obsessive compulsive and attention deficit hyperactivity disorder. A common etiology?. Clin Psychol Rev 19 (1999) 531-552
12. Robbins T.W., and Everitt B.J. Drug addiction: bad habits add up. Nature 398 (1999) 567-570
13. Everitt B.J., and Robbins T.W. Neural systems of reinforcement for drug addiction: From actions to habits to compulsion. Nat Neurosci 8 (2005) 1481-1489
14. Gerdeman G.L., Partridge J.G., Lupica C.R., and Lovinger D.M. It could be habit forming: Drugs of abuse and striatal synaptic plasticity. Trends Neurosci 26 (2003) 184-192
15. Vanderschuren L.J., Di Ciano P., and Everitt B.J. Involvement of the dorsal striatum in cue-controlled cocaine seeking. J Neurosci 25 (2005) 8665-8670
16. Volkow N.D., Wang G.J., Telang F., Fowler J.S., Logan J., Childress A.R., et al. Cocaine cues and dopamine in dorsal striatum: Mechanism of craving in cocaine addiction. J Neurosci 26 (2006) 6583-6588
17. Yin H.H., Knowlton B.J., and Balleine B.W. Lesions of dorsolateral striatum preserve outcome expectancy but disrupt habit formation in instrumental learning. Eur J Neurosci 19 (2004) 181-189
18. Yin H.H., Knowlton B.J., and Balleine B.W. Blockade of NMDA receptors in the dorsomedial striatum prevents action-outcome learning in instrumental conditioning. Eur J Neurosci 22 (2005) 505-512
19. Yin H.H., Knowlton B.J., and Balleine B.W. Inactivation of dorsolateral striatum enhances sensitivity to changes in the action-outcome contingency in instrumental conditioning. Behav Brain Res 166 (2006) 189-196
20. Yin H.H., Ostlund S.B., Knowlton B.J., and Balleine B.W. The role of the dorsomedial striatum in instrumental conditioning. Eur J Neurosci 22 (2005) 513-523
21. Colwill R.M., and Rescorla R.A. Effect of reinforcer devaluation on discriminative control of instrumental behavior. J Exp Psychol Anim Behav Process 16 (1990) 40-47
22. Dickinson A. Actions and habits: The development of behavioural autonomy. Philos Trans R Soc Lond Ser B Biol Sci 308 (1985) 67-78
23. Balleine B.W., and Dickinson A. Goal-directed instrumental action: Contingency and incentive learning and their cortical substrates. Neuropharmacology 37 (1998) 407-419
24. Yin H.H., and Knowlton B.J. The role of the basal ganglia in habit formation. Nat Rev Neurosci 7 (2006) 464-476
25. Holland P.C., and Gallagher M. Amygdala-frontal interactions and reward expectancy. Curr Opin Neurobiol 14 (2004) 148-155
26. Bechara A., Damasio A.R., Damasio H., and Anderson S.W. Insensitivity to future consequences following damage to human prefrontal cortex. Cognition 50 (1994) 7-15
27. Pickens C.L., Saddoris M.P., Setlow B., Gallagher M., Holland P.C., and Schoenbaum G. Different roles for orbitofrontal cortex and basolateral amygdala in a reinforcer devaluation task. J Neurosci 23 (2003) 11078-11084
28. Pickens C.L., Saddoris M.P., Gallagher M., and Holland P.C. Orbitofrontal lesions impair use of cue-outcome associations in a devaluation task. Behav Neurosci 119 (2005) 317-322
29. Ostlund S.B., and Balleine B.W. Orbitofrontal cortex mediates outcome encoding in Pavlovian but not instrumental conditioning. J Neurosci 27 (2007) 4819-4825
30. Valentin V.V., Dickinson A., and O'Doherty J.P. Determining the neural substrates of goal-directed learning in the human brain. J Neurosci 27 (2007) 4019-4046
31. Gottfried J.A., O'Doherty J., and Dolan R.J. Encoding predictive reward value in human amygdala and orbitofrontal cortex. Science 301 (2003) 1104-1107
32. Reynolds B. A review of delay-discounting research with humans: Relations to drug use and gambling. Behav Pharmacology 17 (2006) 651-667
33. Winstanley C.A., Eagle D.M., and Robbins T.W. Behavioral models of impulsivity in relation to ADHD: Translation between clinical and preclinical studies. Clin Psychol Rev 26 (2006) 379-395
34. Simon N.W., Mendex I.A., and Setlow B. Cocaine exposure causes long-term increases in impulsive choice. Behav Neurosci 121 (2007) 543-549
35. Winstanley C.A., Theobald D.E., Cardinal R.N., and Robbins T.W. Contrasting roles of basolateral amygdala and orbitofrontal cortex in impulsive choice. J Neurosci 24 (2004) 4718-4722
36. Chudasama Y., Passetti F., Rhodes S.E., Lopian D., Desai A., and Robbins T.W. Dissociable aspects of performance on the 5-choice serial reaction time task following lesions of the dorsal anterior cingulate, infralimbic and orbitofrontal cortex in the rat: Differential effects on selectivity, impulsivity, and compulsivity. Behav Brain Res 146 (2003) 105-119
37. Eagle D.M., Baunez C., Hutcheson D.M., Lehmann O., Shah A.P., and Robbins T.W. Stop-signal reaction-time task performance: Role of prefrontal cortex and subthalamic nucleus. Cereb Cortex 18 (2007) 178-188
38. Chudasama Y., and Robbins T.W. Dissociable contributions of the orbitofrontal and infralimbic cortex to pavlovian autoshaping and discrimination reversal learning: Further evidence for the functional heterogeneity of the rodent frontal cortex. J Neurosci 23 (2003) 8771-8780
39. Schoenbaum G., Saddoris M.P., and Stalnaker T.A. Reconciling the roles of orbitofrontal cortex in reversal learning and the encoding of outcome expectancies. Ann NY Acad Sci (2007) doi: 10.1196/annals.1401.001.
40. Evans D.W., Lewis M.D., and Iobst E. The role of the orbitofrontal cortex in normally developing compulsive-like behaviors and obsessive-compulsive disorder. Brain Cogn 55 (2004) 220-234
41. Grant J.E., and Potenza M.N. Compulsive aspects of impulse-control disorders. Psychiatry Clin North Am 29 (2006) 539-551
42. Schoenbaum G., and Shaham Y. The role of orbitofrontal cortex in drug addiction: A review of preclinical studies. Biol Psychiatry 63 (2008) 256-262
43. Everitt B.J., and Robbins T.W. Neural systems of reinforcement for drug addiction: From actions to habits to compulsion. Nat Neurosci 8 (2005) 1481-1489
44. Diergaarde L., Pattij T., Poortvliet I., Hogenboom F., de Vries W., Schoffelmeer A.N.M., and De Vries T. Impulsive choice and impulsive action predict vulnerability to distinct stages of nicotine seeking in rats. Biol Psychiatry 63 (2008) 301-308