Study of molecular mechanisms of pro-apoptotic activity of NCX 4040, a novel nitric oxide-releasing aspirin, in colon cancer cell lines

Journal of Translational Medicine

Volumn 5, Issue , 2007, Pages

  Tesei, Anna ^a   Rosetti, Marco ^a   Ulivi, Paola ^a   Fabbri, Francesco ^a   Medri, Laura ^b   Vannini, Ivan ^a   Bolla, Manlio ^c   Amadori, Dino ^a   Zoli, Wainer ^a  

^a DEPARTMENT OF MEDICAL ONCOLOGY   (Italy)

^b MORGAGNI PIERANTONI HOSPITAL   (Italy)

^c NicOx SA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; CASPASE 3; CASPASE 9; CELL PROTEIN; CYCLOOXYGENASE 2; CYTOCHROME C; NCX 4040; NITRIC OXIDE DONOR; NITRIC OXIDE RELEASING ASPIRIN; PROSTAGLANDIN E2; PROTEIN NAG 1; PROTEIN P53; SULFORHODAMINE B; UNCLASSIFIED DRUG; ACETYLSALICYLIC ACID; DRUG DERIVATIVE; NITRIC OXIDE; NITRO DERIVATIVE; NITROPRUSSIDE SODIUM; NONSTEROID ANTIINFLAMMATORY AGENT;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL MEMBRANE POTENTIAL; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DNA REPAIR; DRUG RESPONSE; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE; MOLECULAR MECHANICS; OXIDATIVE STRESS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR GROWTH; WESTERN BLOTTING; CHEMISTRY; COLON TUMOR; CONFORMATION; DRUG EFFECT; PATHOLOGY; PHYSIOLOGY; SECRETION; TUMOR CELL LINE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; ASPIRIN; CELL LINE, TUMOR; COLONIC NEOPLASMS; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIAL MEMBRANES; MOLECULAR CONFORMATION; NITRIC OXIDE; NITRO COMPOUNDS; NITROPRUSSIDE;

EID: 37849018725     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-5-52     Document Type: Article

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