Endomorphin-2 with a β-turn backbone constraint retains the potent μ-opioid receptor agonist properties

Journal of Medicinal Chemistry

Volumn 51, Issue 1, 2008, Pages 173-177

  Tömböly, Csaba ^a   Ballet, Steven ^b   Feytens, Debby ^b   Köver, Katalin E ^c   Borics, Attila ^a   Lovas, Sándor ^d   Al Khrasani, Mahmoud ^e   Fürst, Zsuzsanna ^e   Tóth, Géza ^a   Benyhe, Sándor ^a   Tourwé, Dirk ^b  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c UNIVERSITY OF DEBRECEN   (Hungary)

^d CREIGHTON UNIVERSITY MEDICAL CENTER   (United States)

^e SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOMORPHIN 2; ENDORPHIN DERIVATIVE; MU OPIATE RECEPTOR AGONIST;

AQUEOUS SOLUTION; ARTICLE; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, OPIOID, MU; SOLUTIONS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 37849005357     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm7010222     Document Type: Article

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