Neuroimmune mechanisms in patients with atopic dermatitis during chronic stress

Journal of the European Academy of Dermatology and Venereology

Volumn 22, Issue 1, 2008, Pages 11-18

  Lonne Rahm, Sol Britt ^a   Rickberg, H ^a   El Nour, H ^a   Marin P ^b   Azmitia, E C ^c   Nordlind, K ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c NEW YORK UNIVERSITY   (United States)

Author keywords

Atopic dermatitis; Innervation; Mastcells; Neuropeptides; Receptors; Serotonin; Stress

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CD3 ANTIGEN; HYDROCORTISONE; NEUROPEPTIDE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN TRANSPORTER; SUBSTANCE P;

ACANTHOSIS; ADULT; ANAMNESIS; ARTICLE; ATOPIC DERMATITIS; BASEMENT MEMBRANE; CHRONIC STRESS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DERMIS; DISEASE MARKER; EPIDERMIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOLOGY; IMMUNOREACTIVITY; MALE; MAST CELL; NERVE FIBER; PRIORITY JOURNAL; SALIVARY GLAND; SEROTONINERGIC SYSTEM; SKIN BIOPSY;

ADULT; ANTIGENS, CD3; BIOPSY; CHRONIC DISEASE; DERMATITIS, ATOPIC; FEMALE; HUMANS; HYDROCORTISONE; MALE; MAST CELLS; NEUROIMMUNOMODULATION; NEUROPEPTIDES; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTOR, SEROTONIN, 5-HT2A; SALIVA; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SKIN; STRESS, PSYCHOLOGICAL; UBIQUITIN THIOLESTERASE;

EID: 37749040156     PISSN: 09269959     EISSN: 14683083     Source Type: Journal    
DOI: 10.1111/j.1468-3083.2007.02202.x     Document Type: Article

References (38)

1. Leung DYM, Bieber T. Atopic dermatitis. Lancet 2003; 361: 151-160.
2. Schultz Larsen F. Atopic dermatitis: A genetic-epidemiologic study in a population-based twin sample. J Am Acad Dermatol 1993; 28: 719-723.
3. Pastar Z, Lipozencic J, Ljubojevic S. Etiopathogenesis of atopic dermatitis - an overview. Acta Dermatovenerol Croat 2005; 13: 54-62.
4. Morren MA, Przybilla B, Bamelis M, Heykants B, Reynaers A, Degreef H. Atopic dermatitis: Triggering factors. J Am Acad Dermatol 1994; 31: 467-473.
5. Chuong CM, Nickoloff BJ, Elias PM et al. What is the 'true' function of skin? Exp Dermatol 2002; 11: 159-187.
6. Slominski A, Wortsman J. Neuroendocrinology of the skin. Endocr Rev 2000; 2: 457-487.
7. Steinhoff M, Ständer S, Seeliger S, Ansel JC, Schmelz M, Luger T. Modern aspects of cutaneous neurogenic inflammation. Arch Dermatol 2003; 139: 1479-1488.
8. Lotti T, Bianchi B, Panconesi E. Neuropeptides and skin disorders. The new frontiers of neuro-endocrine-cutaneous immunology. Int J Dermatol 1999; 38: 673-675.
9. Gianetti A, Girolomoni G. Skin reactivity to neuropeptides in atopic dermatitis. Br J Dermatol 1989; 121: 681-688.
10. Ostlere LS, Cowen T, Rustin MH. Neuropeptides in the skin of patients with atopic dermatitis. Clin Exp Dermatol 1995; 20: 462-467.
11. 1 receptor. J Clin Psychiatry 2002; 63: 6-10.
12. Jarvikallio A, Harvima IT, Naukkarinen A. Mast cells, nerves and neuropeptides in atopic dermatitis and nummular eczema. Arch Dermatol Res 2003; 295: 2-7.
13. Slominski A, Wortsman J, Tobin DJ. The cutaneous serotonergic/ melatonergic system: Securing a place under the sun. FASEB J 2005; 19: 176-194.
14. Slominski A, Pisarchik A, Zbytek B, Tobin DJ, Kauser S, Wortsman J. Functional activity of serotoninergic and melatoninergic systems expressed in the skin. J Cell Physiol 2003; 196: 144-153.
15. Vergé D, Calas A. Serotoninergic neurons and serotonin receptors: gains from cytochemical approaches. J Chem Neuroanat 2000; 18: 41-56.
16. Azmitia EC. Modern views on an ancient chemical: Serotonin effects on cell proliferation, maturation, and apoptosis. Brain Res Bull 2001; 56: 413-424.
17. Choi EH, Brown BE, Crumrine D et al. Mechanisms by which psychologic stress alters cutaneous permeability barrier homeostasis and stratum corneum integrity. J Invest Dermatol 2005; 124: 587-595.
18. Graeff FG, Guimarães FS, Andrade TG, Deakin JF. Role of 5-HT in stress, anxiety and depression. Pharmacol Biochem Behav 1996; 54: 129-141.
19. Hökfelt T, Arvidsson U, Cullheim S et al. Multiple messengers in descending serotonin neurons: Localization and functional implications. J Chem Neuroanat 2000; 18: 75-86.
20. Ljung T, Andersson B, Bengtsson BA, Bjorntorp P, Marin P. Inhibition of cortisol secretion by dexamethasone in relation to body fat distribution: A dose-response study. Obes Res 1996; 4: 277-282.
21. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol (Stockh) 1980; 92 (Suppl.): 44-47.
22. Tobin D, Nabarro G, Baart de la Faille H et al. Increased number of immunoreactive nerve fibers in atopic dermatitis. J Allergy Clin Immunol 1992; 90: 613-622.
23. Urashima R, Mihara M. Cutaneous nerves in atopic dermatitis. A histological, immunohistochemical and electron microscopic study. Virchows Arch 1998; 432: 363-370.
24. Bigliardi-Qi M, Lipp B, Sumanovski LT, Buechner SA, Bigliardi PL. Changes of epidermal mu-opiate receptor expression and nerve endings in chronic atopic dermatitis. Dermatology 2005; 210: 91-99.
25. Kitamura H, Yamauchi A, Nakanishi T et al. Effects of inhibition of myo-inositol transport on MDCK cells under hypertonic environment. Am J Physiol 1997; 272: F267-F272.
26. Liang Y, Heilborn JD, Marcusson JA, Johansson O. Increased NGFr immunoreactive, dermal nerve fibers in prurigo nodularis. Eur J Dermatol 1996; 6: 563-567.
27. Hogg S, Dalvi A. Acceleration of onset of action in schedule-induced polydipsia. combinations of SSRI and 5-HT1A and 5-HT1B receptor antagonists. Pharm Biochem Behav 2004; 77: 69-75.
28. Slominski A, Wortsman J, Luger T, Paus R, Solomon S. Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress. Physiol Rev 2000; 80: 979-1020.
29. Slominski A, Zbytek B, Szczesniewski A et al. CRH stimulation of corticosteroids production in melanocytes is mediated by ACTH. Am J Physiol Endocrinol Metab 2005; 288: E701-E706.
30. Pucadyil TJ, Chattopadhyay A. Cholesterol modulates the antagonist-binding function of hippocampal serotonin 1A receptors. Biochim Biophys Acta 2005; 1714: 35-42.
31. Slominski A, Zjawiony J, Wortsman J et al. A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin. Eur J Biochem 2004; 271: 4178-4188.
32. Fernandes C, McKittrick CR, File SE, McEwen BS. Decreased 5-HT 1A and increased 5-HT 2A receptor binding after chronic corticosterone associated with a behavioural indication of depression but not anxiety. Psychoneuroendocrinology 1997; 22: 477-491.
33. Passaretti TV, Wilcox BD, Jeffrey JJ. Serotonin regulation of gene expression in uterine extracellular matrix. reciprocal effects on collagens and collagenase. Mol Cell Endocrinol 1996; 120: 125-132.
34. Hayashi T, Sumi D, Matsui-Hirai H et al. Sarpogrelate HCl, a selective 5-HT2A antagonist, retards the progression of atherosclerosis through a novel mechanism. Atherosclerosis 2003; 168: 23-31.
35. Vásquez DM, López JF, Van Hoers H, Watson SJ, Levine S. Maternal deprivation regulates serotonin 1A and 2A receptors in the infant brain. Brain Res 2000; 855: 76-82.
36. Kervinen H, Kaartinen M, Mäkynen H, Palosuo T, Manttari M, Kovanen PT. Serum tryptase levels in acute coronary syndromes. Int J Cardiol 2005; 104: 138-143.
37. Azmitia EC, Yu I, Akbari HM, Kheck N, Whitaker-Azmitia PM, Marshak DR. Antipeptide antibodies against the 5-HT1A receptor. J Chem Neuroanat 1992; 5: 289-298.
38. Wu C, Yoder EJ, Shih J et al. Development and characterization of monoclonal antibodies specific to the serotonin 5-HT2A receptor. J Histochem Cytochem 1998; 46: 811-824.