Neuroserpin polymorphisms and stroke risk in a biracial population: The stroke prevention in young women study

BMC Neurology

Volumn 7, Issue , 2007, Pages

  Cole, John W ^a,b   Naj, Adam C ^c   O'Connell, Jeffrey R ^b   Stine, Oscar C ^b   Sorkin, John D ^a   Wozniak, Marcella A ^a,b   Stern, Barney J ^a,b   Yepes, Manuel ^d   Lawrence, Daniel A ^e   Reinhart, Laurie J ^b   Strickland, Dudley K ^b   Mitchell, Braxton D ^b   Kittner, Steven J ^a,b  

^a BALTIMORE VA MEDICAL CENTER   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROSERPIN; SERINE PROTEINASE INHIBITOR; NEUROPEPTIDE;

ADOLESCENT; ADULT; AFRICAN AMERICAN; AGE DISTRIBUTION; ALLELE; ARTICLE; CAUCASIAN; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; FEMALE; GENDER; GENE FREQUENCY; GENE LOCATION; GENETIC ASSOCIATION; HAPLOTYPE MAP; HUMAN; INTRON; MAJOR CLINICAL STUDY; ONSET AGE; POPULATION BASED CASE CONTROL STUDY; RACE DIFFERENCE; RISK; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE; CASE CONTROL STUDY; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HEALTH CARE PLANNING; MIDDLE AGED; NEGRO; RISK FACTOR; STROKE;

ADOLESCENT; ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; COMMUNITY HEALTH PLANNING; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MIDDLE AGED; NEUROPEPTIDES; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SERPINS; STROKE;

EID: 37749032768     PISSN: None     EISSN: 14712377     Source Type: Journal    
DOI: 10.1186/1471-2377-7-37     Document Type: Article

References (22)

1. Hastings GA Coleman TA Haudenschild CC Stefansson S Smith EP Barthlow R Cherry S Sandkvist M Lawrence DA Neuroserpin, a Brain-associated Inhibitor of Tissue Plasminogen Activator Is Localized Primarily in Neurons J Biol Chem 1997, 272:33062-7 10.1074/jbc.272.52.33062 9407089
2. Yepes M Sandkvist M Wong MK Coleman TA Smith E Cohan SL Lawrence DA Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis Blood 2000, 96:569-76 10887120
3. Cinelli P Madani R Tsuzuki N Vallet P Arras M Zhao CN Osterwalder T Rulicke T Sonderegger P Neuroserpin, a neuroprotective factor in focal ischemic stroke Mol Cell Neurosci 2001, 18:443-57 10.1006/mcne.2001.1028 11922137
4. Yepes M Sandkvist M Moore EG Bugge TH Strickland DK Lawrence DA Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein J Clin Invest 2003 112 1533 40 259131 14617754 10.1172/JCI200319212
5. Krueger SR Ghisu GP Cinelli P Gschwend TP Osterwalser T Wolfer D Sonderegger P Expression of neuroserpin an inhibitor of tissue plasminogen activator, in the developing and adult nervous system of the mouse J Neurosci 1997, 17:8984-96 9364046
6. Miranda E Lomas DA Neuroserpin: A serpin to think about Cell Mol Life Sci 2006, 63:709-22 10.1007/s00018-005-5077-4 16465451
7. Yepes M Lawrence DA Neuroserpin: A selective inhibitor of tissue-type plasminogen activator in the central nervous system Thromb Haemost 2004, 91:457-64 14983220
8. Davis RL Shrimpton AE Carrell RW Lomas DA Gerhard L Baumann B Lawrence DA Yepes M Kim TS Ghetti B Piccardo P Takao M Lacbawan F Muenke M Sifers RN Bradshaw CB Kent PF Collins GH Larocca D Holohan PD Association between conformational mutations in neuroserpin and onset and severity of dementia Lancet 2002, 359:2242-7 10.1016/S0140-6736(02)09293-0 12103288
9. Lomas DA Carrell RW Serpinopathies and the conformational dementias Nat Rev Genet 2002, 3:759-68 10.1038/nrg907 12360234
10. Davis RL Holohan PD Shrimpton AE Tatum AH Daucher J Collins GH Todd R Bradshaw C Kent P Feiglin D Rosenbaum A Yerby MS Shaw CM Lacbawan F Lawrence DA Familial encephalopathy with neuroserpin inclusion bodies Am J Pathol 1999, 155:1901-13 10595921
11. Benchenane K Berezowski V Ali C Fernandez-Monreal M Lopez-Atalaya JP Brillault J Chuquet J Nouvelot A MacKenzie ET Bu G Cecchelli R Touzani O Vivien D Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis Circulation 2005, 111:2241-49 10.1161/ 01.CIR.0000163542.48611.A2 15851587
12. Berger P Kozlov SV Cinelli P Kruger SR Vogt L Sonderegger P Neuronal depolarization enhances the transcription of the neuronal serine protease inhibitor neuroserpin Mol Cell Neurosci 1999, 14:455-67 10.1006/ mcne.1999.0804 10656253
13. Johnson CJ Kittner SJ McCarter RJ Sloan MA Stern BJ Buchholz D Price TR Interrater reliability of an etiologic classification of ischemic stroke Stroke 1995, 26:46-51 7839396
14. Kittner SJ Stern BJ Feeser BR Hebel R Nagey DA Buchholz DW Earley CJ Johnson CJ Macko RF Sloan MA Wityk RJ Wozniak MA Pregnancy and the risk of stroke N Engl J Med 1996, 335:768-774 1479545 8703181 10.1056/ NEJM199609123351102
15. Kittner SJ Stern BJ Wozniak M Buchholz DW Earley CJ Feeser BR Johnson CJ Macko RF McCarter RJ Price TR Sherwin R Sloan MA Wityk RJ Cerebral infarction in young adults: The Baltimore-Washington Cooperative Young Stroke Study Neurology 1998, 50:890-4 9566368
16. Meschia JF Brown RD Jr Brott TG Chukwudelunzu FE Hardy J Rich SS The Siblings With Ischemic Stroke Study (SWISS) protocol BMC Med Genet 2002, 3:1 79001 11882254 10.1186/1471-2350-3-1
17. The International HapMap Consortium The International HapMap Project Nature 2003, 426:789-796 http://www.hapmap.org/ 10.1038/nature02168 14685227
18. Barrett JC Fry B Maller J Daly MJ Haploview: Analysis and visualization of LD and haplotype maps Bioinformatics 2005, 21:263-265 http://www.broad.mit.edu/mpg/haploview/ 10.1093/bioinformatics/bth457 15297300
19. Schaid DJ Rowland CM Tines DE Jacobson RM Poland GA Score tests for association between traits and haplotypes when linkage phase is ambiguous Am J Hum Gen 2002, 70:425-34 http://mayoresearch.mayo.edu/mayo/ research/biostat/schaid.cfm 10.1086/338688
20. R Development Core Team R: A language and environment for statistical computing R Foundation for Statistical Computing, Vienna, Austria 2005 http://www.R-project.org ISBN 3-900051-07-0
21. Clayton D SNPHAP - A program for estimating frequencies of large haplotypes of SNPs Cambridge Institute for Medical Research, Addenbrooke's Hospital, Cambridge, UK http://www-gene.cimr.cam.ac.uk/ clayton/software/snphap.txt
22. Zhang Z Zhang L Yepes M Jiang Q Li Q Arniego P Coleman TA Lawrence DA Chopp M Adjuvant treatment with neuroserpin increases the therapeutic window for tissue-type plasminogen activator administration in a rat model of embolic stroke Circulation 2002, 106:740-5 12163437