Computer-aided design of polyketides with the required properties

Biomeditsinskaya Khimiya

Volumn 53, Issue 5, 2007, Pages 522-531

  Sergeyko, A P ^a   Stepanchikova, A V ^a   Sobolev, B N ^a   Zotchev, S B ^b   Lagunin, A A ^a   Filimonov, D A ^a   Poroikov, V V ^a  

^a INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

Biological activity prediction; Macrolides; Polyketide synthase; Polyketides; Selection substances with required properties; Virtual library

Indexed keywords

EID: 37749029830     PISSN: 23106905     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Hopwood D.A., Sherman D.H. (1990) Annu. Rev. Genet., 24, 37-66.
2. Donadio S., Staver M.J., McAlpine J.B., Swanson S.J., Katz L. (1991) Science, 252(5006), 675-679.
3. Omura S. (2002) Macrolide antibiotics: chemistry, biology, and practice, 2nd edn. Academic Press: New York.
4. Kosan Biosciences, http://www.kosan.com/technology-platform.html.
5. Aparicio J.F., Caffrey P., Gil J.A., Zotchev S.B. (2003) Appl. Microbiol. Biotechnol., 61, 179-188.
6. Ikeda H., Nonomiya T., Usami M., Ohta T., Omura S. (1999) Proc. Natl. Acad. Sci. USA, 96, 9509-9514.
7. Waldron C., Madduri K., Crawford K., Merlo D.J., Treadway P., Broughton M.C., Baltz R. (2000) Antonie Van Leeuwenhoek, 78(3-4), 385-390.
8. Waldron C., Matsushima P., Rosteck P.R. Jr., Broughton M.C., Turner J., Madduri K., Crawford K.P., Merlo D.J., Baltz R.H. (2001) Chem. Biol., 8, 487499.
9. Anzai Y., Saito N., Tanaka M., Kinoshita K., Koyama Y, Kato F. (2003) FEMS Microbiol. Lett., 218, 135-141.
10. Schupp T., Toupet C., Cluzel B., Neff S., Hill S., Beck J.J., Ligon J.M. (1995) J. Bacteriol., 177, 3673-3679.
11. McDaniel R., Thamchaipenet A., Gustafsson C., Fu H., Betlach M., Ashley G. (1999) Proc. Natl. Acad. Sci. USA., 96, 1846-1851.
12. Bentley R., Bennett J. W. (1999) Annu. Rev. Microbiol., 53, 411-446.
13. Reeves C.D., Murli S., Ashley G.W., Piagentini M., Hutchinson C.R., McDaniel R. (2001) Biochemistry, 40, 15464-15470.
14. McDaniel R., Welch M., Hutchinson C.R. (2005) Chem. Rev., 105, 543-558.
15. Gonzalez-Lergier J., Broadbelt L.J., Hatzimanikatis V. (2005) J. Am. Chem. Soc., 127, 9930-9938.
16. Russian source
17. Russian source
18. http://www.mdl.com.
19. Zotchev S.B., Stepanchikova A.V., Sergeyko A.P., Sobolev B.N., Filimonov D.A., Poroikov V.V. (2006) J. Med. Chem., 49, 2077-2087.
20. Poroikov V., Lagunin A., Filimonov D. (2004) in: QSAR and Molecular Modelling in Rational Design of Bioactive Molecules. (E. Aki Sener and I. Yalcin eds.) CADD & D Society, Ankara (Turkey), pp. 514-515.
21. Russian source
22. http://www.chemnetbase.com/index.html.
23. Aronson J.K. (2006) Meyler's side effects of drugs, 15-th ed. Elsevier.
24. Kostrubsky V.E., Strom S.C., Hanson J., Urda E., Rose K., Burliegh J., Zocharski P., Cai H., Sinclair J.F., Sahi J. (2003) Toxicol. Sci., 76, 220-228.