DeltaFosB accumulation in ventro-medial caudate underlies the induction but not the expression of behavioral sensitization by both repeated amphetamine and stress

European Journal of Neuroscience

Volumn 27, Issue 1, 2008, Pages 191-201

  Conversi, D ^a,b   Bonito Oliva, A ^a   Orsini, C ^a,b   Colelli, V ^a   Cabib, S ^a,b,c  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Accumbens core; FosB DeltaFosB; Inducible transcription factors; Mouse; Plasticity; Restraint

Indexed keywords

AMPHETAMINE; PROTEIN FOS; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DELTA FOSB; TRANSCRIPTION FACTOR FOSB;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; C57BL 6 MOUSE; CAUDATE NUCLEUS; CONTROLLED STUDY; ENVIRONMENT; IMMOBILIZATION STRESS; LOCOMOTION; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; THALAMUS VENTRAL NUCLEUS;

AMPHETAMINE; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; CAUDATE NUCLEUS; CENTRAL NERVOUS SYSTEM STIMULANTS; DRUG ADMINISTRATION SCHEDULE; GENE EXPRESSION; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; ONCOGENE PROTEINS V-FOS; PROTO-ONCOGENE PROTEINS C-FOS; STRESS;

EID: 37749027184     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.06003.x     Document Type: Article

References (64)

1. Abramoff, M.D., Magelhaes, R.J. Ram, S.J. (2004) Image processing with Image J. J. Biophoton. Int., 11, 36 42.
2. Alibhai, I.N., Green, T.A., Potashkin, J.A. Nestler, E.J. (2007) Regulation of fosB and DeltafosB mRNA expression: in vivo and in vitro studies. Brain Res., 1143, 22 33.
3. Anagnostaras, S.G. Robinson, T.E. (1996) Sensitization to the psychomotor stimulant effects of amphetamine modulation by associative learning. Behav. Neurosci., 110, 1397 1414.
4. Anagnostaras, S.G., Schallert, T. Robinson, T.E. (2002) Memory processes governing amphetamine-induced psychomotor sensitization. Neuropsychopharmacology, 26, 703 715.
5. Antelman, S.M., Eichler, A.J., Black, C.A. Kocan, D. (1980) Interchangeability of stress and amphetamine in sensitization. Science, 207, 329 331.
6. Badiani, A., Oates, M.M., Day, H.E., Watson, S.J., Akil, H. Robinson, T.E. (1998) Amphetamine-induced behavior, dopamine release, and c-fos mRNA expression: modulation by environmental novelty. J. Neurosci., 18, 10 579 593.
7. Brady, K.T. Sinha, R. (2005) Co-occurring mental and substance use disorders: the neurobiological effects of chronic stress. Am. J. Psychiatry, 162, 1483 1493.
8. Brenhouse, H.C. Stellar, J.R. (2006) c-Fos and deltaFosB expression are differentially altered in distinct subregions of the nucleus accumbens shell in cocaine-sensitized rats. Neuroscience, 137, 773 780.
9. Cabib, S. (1993) Strain-dependent behavioural sensitization to amphetamine role of environmental influences. Behav. Pharmacol., 4, 367 374.
10. Carey, R.J. Gui, J. (1998) Cocaine conditioning and cocaine sensitization what is the relationship? Behav. Brain Res., 92, 67 76.
11. Chao, J. Nestler, E.J. (2004) Molecular neurobiology of drug addiction. Annu. Rev. Med., 55, 13 32.
12. Chen, J., Nye, H.E., Kelz, M.B., Hiroi, N., Nakabeppu, Y., Hope, B.T. Nestler, E.J. (1995) Regulation of delta FosB and FosB-like proteins by electroconvulsive seizure and cocaine treatments. Mol. Pharmacol., 48, 880 889.
13. Conversi, D., Orsini, C. Cabib, S. (2004) Distinct patterns of Fos expression induced by systemic amphetamine in the striatal complex of C57BL/6JICo and DBA/2JICo inbred strains of mice. Brain Res., 1025, 59 66.
14. Conversi, D., Bonito-Oliva, A., Orsini, C. Cabib, S. (2006) Habituation to the test cage influences amphetamine-induced locomotion and Fos expression and increases FosB/DeltaFosB-like immunoreactivity in mice. Neuroscience, 141, 597 605.
15. Crombag, H.S., Jedynak, J.P., Redmond, K., Robinson, T.E. Hope, B.T. (2002) Locomotor sensitization to cocaine is associated with increased Fos expression in the accumbens, but not in the caudate. Behav. Brain Res., 136, 455 462.
16. Di Ciano, P. Everitt, B.J. (2004) Direct interactions between the basolateral amygdala and nucleus accumbens core underlie cocaine-seeking behavior by rats. J. Neurosci., 24, 7167 7173.
17. Fuchs, R.A., Evans, K.A., Parker, M.C. See, R.E. (2004) Differential involvement of the core and shell subregions of the nucleus accumbens in conditioned cue-induced reinstatement of cocaine seeking in rats. Psychopharmacology, 176, 459 465.
18. Harris, G.C., Hummel, M., Wimmer, M., Mague, S.D. Aston-Jones, G. (2007) Elevations of FosB in the nucleus accumbens during forced cocaine abstinence correlate with divergent changes in reward function. Neuroscience, June 6 (Epub ahead of print).
19. Herdegen, T. Leah, J.D. (1998) Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res. Brain Res. Rev., 28, 370 490.
20. Hope, B.T., Nye, H.E., Kelz, M.B., Self, D.W., Iadarola, M.J., Nakabeppu, Y., Duman, R.S. Nestler, E.J. (1994) Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments. Neuron, 13, 1235 1244.
21. Hope, B.T., Simmons, D.E., Mitchell, T.B., Kreuter, J.D. Mattson, B.J. (2006) Cocaine-induced locomotor activity and Fos expression in nucleus accumbens are sensitized for 6 months after repeated cocaine administration outside the home cage. Eur. J. Neurosci., 24, 867 875.
22. Ito, R., Robbins, T.W. Everitt, B.J. (2004) Differential control over cocaine-seeking behavior by nucleus accumbens core and shell. Nat. Neurosci., 7, 389 397.
23. Kalivas, P.W. Stewart, J. (1991) Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Res. Brain Res. Rev., 16, 223 244.
24. Kelz, M.B., Chen, J., Carlezon, W.A. Jr., Whisler, K., Gilden, L., Beckmann, A.M., Steffen, C., Zhang, Y.J., Marotti, L., Self, D.W., Tkatch, T., Baranauskas, G., Surmeier, D.J., Neve, R.L., Duman, R.S., Picciotto, M.R. Nestler, E.J. (1999) Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine. Nature, 401, 272 276.
25. Laruelle, M. (2000) The role of endogenous sensitization in the pathophysiology of schizophrenia: implications from recent brain imaging studies. Brain Res. Brain Res. Rev., 31, 371 384.
26. Li, Y., Acerbo, M.J. Robinson, T.E. (2004) The induction of behavioural sensitization is associated with cocaine-induced structural plasticity in the core (but not shell) of the nucleus accumbens. Eur. J. Neurosci., 20, 1647 1654.
27. Lieberman, J.A., Perkins, D., Belger, A., Chakos, M., Jarskog, F., Boteva, K. Gilmore, J. (2001) The early stages of schizophrenia: speculations on pathogenesis, pathophysiology, and therapeutic approaches. Biol. Psychiatry, 50, 884 897.
28. Marinelli, M. Piazza, V. (2002) Interaction between glucocorticoid hormones, stress and psychostimulant drugs. Eur. J. Neurosci., 16, 387 394.
29. Marttila, K., Raattamaa, H. Ahtee, L. (2006) Effects of chronic nicotine administration and its withdrawal on striatal FosB/DeltaFosB and c-Fos expression in rats and mice. Neuropharmacology, 51, 44 51.
30. McClung, C.A., Ulery, P.G., Perrotti, L.I., Zachariou, V., Berton, O. Nestler, E.J. (2004) DeltaFosB a molecular switch for long-term adaptation in the brain. Brain Res. Mol. Brain Res., 132, 146 154.
31. Melia, K.R., Ryabinin, A.E., Schroeder, R., Bloom, F.E. Wilson, M.C. (1994) Induction and habituation of immediate early gene expression in rat brain by acute and repeated restraint stress. J. Neurosci., 14, 5929 5938.
32. Miller, C.A. Marshall, J.F. (2004) Altered prelimbic cortex output during cue-elicited drug seeking. J. Neurosci., 24, 6889 6897.
33. Miller, C.A. Marshall, J.F. (2005a) Molecular substrates for retrieval and reconsolidation of cocaine-associated contextual memory. Neuron, 47, 873 884.
34. Miller, C.A. Marshall, J.F. (2005b) Altered Fos expression in neural pathways underlying cue-elicited drug seeking in the rat. Eur. J. Neurosci., 21, 1385 1393.
35. Montag-Sallaz, M., Welzl, H., Kuhl, D., Montag, D. Schachner, M. (1999) Novelty-induced increased expression of immediate-early genes c-fos and arg 3.1 in the mouse brain. J. Neurobiol., 38, 234 246.
36. Nikulina, E.M., Covington, H.E. 3rd., Ganschow, L., Hammer, R.P. Jr. Miczek, K.A. (2004) Long-term behavioral and neuronal cross-sensitization to amphetamine induced by repeated brief social defeat stress: Fos in the ventral tegmental area and amygdala. Neuroscience, 123, 857 865.
37. Nye, H.E. Nestler, E.J. (1996) Induction of chronic Fos-related antigens in rat brain by chronic morphine administration. Mol. Pharmacol., 49, 636 645.
38. Nye, H.E., Hope, B.T., Kelz, M.B., Iadarola, M. Nestler, E.J. (1995) Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens. J. Pharmacol. Exp. Ther., 275, 1671 1680.
39. Oliverio, A., Castellano, C. Puglisi-Allegra, S. (1983) Anticonvulsant effects of stress role of endogenous opioids. Brain Res., 271, 193 195.
40. Ostrander, M.M., Badiani, A., Day, H.E., Norton, C.S., Watson, S.J., Akil, H. Robinson, T.E. (2003) Environmental context and drug history modulate amphetamine-induced c-fos mRNA expression in the basal ganglia, central extended amygdala, and associated limbic forebrain. Neuroscience, 120, 551 571.
41. Paolone, G., Conversi, D., Caprioli, D., Bianco, P.D., Nencini, P., Cabib, S. Badiani, A. (2007) Modulatory effect of environmental context and drug history on heroin-induced psychomotor activity and fos protein expression in the rat brain. Neuropsychopharmacology, March 28 (Epub ahead of print).
42. Paxinos, G. Franklin, K.B.J. (2001) The Mouse Brain in Stereotaxic Coordinates. Academic Press, San Diego.
43. Perrotti, L.I., Hadeishi, Y., Ulery, P.G., Barrot, M., Monteggia, L., Duman, R.S. Nestler, E.J. (2004) Induction of deltaFosB in reward-related brain structures after chronic stress. J. Neurosci., 24, 10 594 10 602.
44. Perrotti, L.I., Bolanos, C.A., Choi, K.H., Russo, S.J., Edwards, S., Ulery, P.G., Wallace, D.L., Self, D.W., Nestler, E.J. Barrot, M. (2005) DeltaFosB accumulates in a GABAergic cell population in the posterior tail of the ventral tegmental area after psychostimulant treatment. Eur. J. Neurosci., 21, 2817 2824.
45. Pich, E.M., Pagliusi, S.R., Tessari, M., Talabot-Ayer, D., Hooft van Huijsduijnen, R. Chiamulera, C. (1997) Common neural substrates for the addictive properties of nicotine and cocaine. Science, 275, 83 86.
46. Pierce, R.C. Kalivas, P.W. (1997) A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants. Brain Res. Brain Res. Rev., 25, 192 216.
47. Prasad, B.M., Sorg, B.A., Ulibarri, C. Kalivas, P.W. (1995) Sensitization to stress and psychostimulants. Involvement of dopamine transmission versus the HPA axis. Ann. N.Y. Acad. Sci., 771, 617 625.
48. Robinson, T.E. Becker, J.B. (1986) Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis. Brain Res., 396, 157 198.
49. Robinson, T.E. Berridge, K.C. (1993) The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res. Brain Res. Rev., 18, 247 291.
50. Robinson, T.E. Berridge, K.C. (2000) The psychology and neurobiology of addiction: an incentive-sensitization view. Addiction, 95, 2S91 117.
51. Robinson, T.E. Berridge, K.C. (2001) Incentive-sensitization and addiction. Addiction, 96, 103 114.
52. Robinson, T.E. Berridge, K.C. (2003) Addiction. Annu. Rev. Psychol., 54, 25 53.
53. Robinson, T.E. Kolb, B. (2004) Structural plasticity associated with exposure to drugs of abuse. Neuropharmacology, 47 (Suppl. 1 33 46.
54. Robinson, T.E., Angus, A.L. Becker, J.B. (1985) Sensitization to stress: the enduring effects of prior stress on amphetamine-induced rotational behavior. Life Sci., 37, 1039 1042.
55. Steketee, J.D., Sorg, B.A. Kalivas, P.W. (1992) The role of the nucleus accumbens in sensitization to drugs of abuse. Prog. Neuropsychopharmacol. Biol. Psychiatry, 16, 237 246.
56. Stewart, J. Vezina, P. (1991) Extinction procedures abolish conditioned stimulus control but spare sensitized responding to amphetamine. Behav. Pharmacol., 2, 65 71.
57. Tenn, C.C., Fletcher, P.J. Kapur, S. (2005) A putative animal model of the 'prodromal' state of schizophrenia. Biol. Psychiatry, 57, 586 593.
58. Thompson, J.L., Pogue-Geile, M.F. Grace, A.A. (2004) Developmental pathology, dopamine, and stress: a model for the age of onset of schizophrenia symptoms. Schizophr. Bull., 30, 875 900.
59. Tirelli, E., Laviola, G. Adriani, W. (2003) Ontogenesis of behavioral sensitization and conditioned place preference induced by psychostimulants in laboratory rodents. Neurosci. Biobehav. Rev., 27, 163 178.
60. Tirelli, E., Michel, A. Brabant, C. (2005) Cocaine-conditioned activity persists for a longer time than cocaine-sensitized activity in mice: implications for the theories using Pavlovian excitatory conditioning to explain the context-specificity of sensitization. Behav. Brain Res., 165, 18 25.
61. Uslaner, J., Badiani, A., Day, H.E., Watson, S.J., Akil, H. Robinson, T.E. (2001) Environmental context modulates the ability of cocaine and amphetamine to induce c-fos mRNA expression in the neocortex, caudate nucleus, and nucleus accumbens. Brain Res., 920, 106 116.
62. Vanderschuren, L.J. Kalivas, P.W. (2000) Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies. Psychopharmacology, 151, 99 120.
63. Vanderschuren, L.J., Schoffelmmer, A.N., Van Leeuwen, S.D., Hof, L., Jonker, A.J. Voorn, P. (2002) Compartment-specific changes in striatal neuronal activity during expression of amphetamine sensitization are the result of drug hypersensitivity. Eur. J. Neurosci, 16, 2462 2468.
64. Ventura, R., Alcaro, A., Cabib, S., Conversi, D., Mandolesi, L. Puglisi-Allegra, S. (2004) Dopamine in the medial prefrontal cortex controls genotype-dependent effects of amphetamine on mesoaccumbens dopamine release and locomotion. Neuropsychopharmacology, 29, 72 80.