Cerebral perfusion correlates of conversion to Alzheimer's disease in amnestic mild cognitive impairment

Journal of Neurology

Volumn 254, Issue 12, 2007, Pages 1698-1707

  Caroli, A ^a   Testa, C ^a,b   Geroldi, C ^a   Nobili, F ^c   Barnden, L R ^d   Guerra, U P ^e   Bonetti, M ^f   Frisoni, G B ^a  

^a IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^b UNIVERSITY OF UDINE   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d QUEEN ELIZABETH HOSPITAL   (Australia)

^e OSPEDALI RIUNITI   (Italy)

^f Istituto Clinico Citta di Brescia   (Italy)

Author keywords

Conversion; Mild cognitive impairment; SPECT; SPET

Indexed keywords

CYSTEINE ETHYL ESTER TC 99M;

AGED; ALZHEIMER DISEASE; AMNESIA; ARTICLE; BRAIN ATROPHY; BRAIN PERFUSION; BRAIN SCINTISCANNING; CLINICAL ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; FEMALE; GRAY MATTER; HUMAN; MALE; MORPHOMETRICS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STATISTICAL ANALYSIS; SUBICULUM;

AGED; ALZHEIMER DISEASE; AMNESIA; ANALYSIS OF VARIANCE; BRAIN MAPPING; CEREBROVASCULAR CIRCULATION; DISEASE PROGRESSION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; TECHNETIUM TC 99M EXAMETAZIME; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 37749023779     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-007-0631-7     Document Type: Article

References (53)

1. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E (1999) Mild cognitive impairment: clinical characterization and outcome. Arch Neurol 56:303-308
2. Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV, Ritchie K, Rossor M, Thal L, Winblad B (2001) Current concepts in mild cognitive impairment. Arch Neurol 58:1985-1992
3. Flicker C, Ferris SH, Reisberg B (1991) Mild cognitive impairment in the elderly: predictors of dementia. Neurology 41:1006-1009
4. Visser PJ, Kester A, Jolles J, Verhey F (2006) Ten-year risk of dementia in subjects with mild cognitive impairment. Neurology 67:1201-1207
5. Bennett DA, Wilson RS, Schneider JA, Evans DA, Beckett LA, Aggarwal NT, Barnes LL, Fox JH, Back J (2002) Natural history of mild cognitive impairment in older persons. Neurology 59:198-205
6. Larrieu S, Letenneur L, Orgogozo JM, Fabrigoule C, Amieva H, Le Carret N, Barberger-Gateau P, Dartigues JF (2002) Incidence and outcomes of mild cognitive impairment in a populationbased prospective cohort. Neurology 59:1594-1599
7. Small AS (2005) Alzheimer disease, in living color. Nat Neurosci 8:404-405
8. Benson DF, Kuhl DE, Hawkins RA, Phelps ME, Cummings JL, Tsai SY (1983) The fluorodeoxyglucose 18F scan in Alzheimer's disease and multiinfarct dementia. Arch Neurol 40:711-714
9. Minoshima S, Giordani B, Berent S, Frey KA, Foster NL, Kuhl DE (1997) Metabolic reduction in the posterior cingulated cortex in very early Alzheimer's disease. Ann Neurol 42:85-94
10. Cabranes JA, De Juan R, Encinas M, Marcos A, Gil P, Fernandez C, De Ugarte C, Barabash A (2004) Relevance of functional neuroimaging in the progression of mild cognitive impairment. Neurol Res 26:496-501
11. 99mTc-ECD SPET as a marker of progression of mild cognitive impairment to Alzheimer's disease. Eur J Nucl Med Mol Imaging 30:1473-1480
12. Chetelat G, Desgranges B, De La Sayette V, Viader F, Eustache F, Baron JC (2003) Mild cognitive impairment: Can FDG-PET predict who is to rapidly convert to Alzheimer's disease? Neurology 60:1374-1377
13. Hirao K, Ohnishi T, Hirata Y, Yamashita F, Mori T, Moriguchi Y, Matsuda H, Nemoto K, Imabayashi E, Yamada M, Iwamoto T, Arima K, Asada T (2005) The prediction of rapid conversion to Alzheimer's disease in mild cognitive impairment using regional cerebral blood flow SPECT. Neuroimage 28:1014-1021
14. Huang C, Wahlund LO, Svensson L, Winblad B (2002) Cingulate cortex hypoperfusion predicts Alzheimer's disease in mild cognitive impairment. BMC Neurol 2:9-14
15. Ishiwata A, Sakayori O, Minoshima S, Mizumura S, Kitamura S, Katayama Y (2006) Preclinical evidence of Alzheimer changes in progressive mild cognitive impairment: a qualitative and quantitative SPECT study. Acta Neurol Scand 114:91-96
16. Anchisi D, Borroni B, Franceschi M, Kerrouche N, Kalbe E, Beuthien-Beumann B, Cappa S, Lenz O, Ludecke S, Marcone A, Miele R, Ortelli P, Padovani A, Pelati O, Pupi A, Scarpini E, Weisenbach S, Herholz K, Salmon E, Holthoff V, Sorbi S, Fazio F, Perani D (2005) Heterogeneity of Brain Glucose Metabolism in Mild Cognitive Impairment and Clinical Progression to Alzheimer Disease. Arch Neurol 62:1728-1733
17. Drzezga A, Lautenschlager N, Siebner H, Riemenschneider M, Willoch F, Minoshima S, Schwaiger M, Kurz A (2003) Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study. Eur J Nucl Med Mol Imaging 30:1104-1113
18. 99mTc-ECD SPECT and neuropsychological studies in MCI for the assessment of conversion to AD. Neurobiol Aging 27:24-31
19. Shulman KI (2000) Clock-drawing: is it the ideal cognitive screening test? Int J Geriatr Psychiatry 15:548-561
20. Giovagnoli AR, Del Pesce M, Mascheroni S, Simoncelli M, Laiacona M, Capitani E (1996) Trail making test: normative values from 287 normal adult controls. Ital J Neurol Sci 17:305-309
21. Basso A, Capitani E, Laiacona M (1987) Raven's coloured progressive matrices: normative values on 305 adult normal controls. Funct Neurol 2:189-194
22. Spinnler H, Tognoni G (1987) Standardizzazione e taratura italiana di test neurologici. Ital J Neurol Sci 8(Suppl):47-50
23. Novelli G, Papagno C, Capitani E, Laiacona M, Cappa SF, Vallar G (1986) Tre test clinici di ricerca e produzione lessicale. Taratura su soggetti normali. Arch Psicol Neurol Psichiatr 47:477-506
24. Caffarra P, Vezzadini G, Dieci F, Zonato F, Venneri A (2002) Rey-Osterrieth complex figure: normative values in an Italian population sample. Neurol Sci 22:443-447
25. Radloff LS (1997) The CES-D scale: A self-report depression scale for research in the general population. Appl Psychol Measure 1:385-401
26. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34:939-944
27. Erkinjuntti T, Inzitari D, Pantoni L, Wallin A, Scheltens P, Rockwood K, Roman GC, Chui H, Desmond DW (2000) Research criteria for subcortical vascular dementia in clinical trials. J Neural Transm Suppl 59:23-30
28. McKeith IG, Ballard CG, Perry RH, Ince PG, O'Brien JT, Neill D, Lowery K, Jaros E, Barber R, Thomson P, Swann A, Fairbairn AF, Perry EK (2000) Prospective validation of consensus criteria for the diagnosis of dementia with Lewy bodies. Neurology 54:1050-1058
29. Knopman DS, Boeve BF, Parisi JE, Dickson DW, Smith GE, Ivnik RJ, Josephs KA, Petersen RC (2005) Antemortem Diagnosis of Frontotemporal Lobar Degeneration. Ann Neurol 57:480-488
30. Riello R, Sabattoli F, Beltramello A, Bonetti M, Bono G, Falini A, Magnani G, Minonzio G, Piovan E, Alaimo G, Ettori M, Galluzzi S, Locatelli E, Noiszewska M, Testa C, Frisoni GB (2005) Brain volumes in healthy adults aged 40 years and over: a voxel based morphometry study. Aging Clin Exp Res 17:329-336
31. Caroli A, Testa C, Geroldi C, Nobili F, Guerra UP, Bonetti M, Frisoni GB (2007) Brain perfusion correlates of medial temporal lobe atrophy and white matter hyperintensities in mild cognitive impairment. J Neurol, epub ahead of print
32. Rorden C, Brett M (2000): Stereotaxic display of brain lesions. Behav Neurol 12:191-200
33. SPM, Statistical Parametric Mapping, version 2 (2002). London: Functional Imaging Laboratory. Available at: http://www. fil. ion. ucl. ac. uk/spm/ software/spm2
34. Frisoni GB, Testa C, Sabattoli F, Beltramello A, Soininen H, Laakso MP (2005) Structural correlates of early and late onset Alzheimer's disease: voxel based morphometric study. J Neurol Neurosurg Psychiatry 76:112-114
35. Filippini N, Scassellati C, Boccardi M, Pievani M, Testa C, Bocchio-Chiavetto L, Frisoni GB, Gennarelli M (2006) Influence of serotonin receptor 2A His452Tyr polymorphism on brain temporal structures: a volumetric MR study. Eur J Hum Genet 14:443-449
36. DISPLAY. Brain Imaging Center - Montreal Neurological Institute. Available at: http://www. bic. mni. mcgill. ca/software
37. Friston KJ, Worsley KJ, Frackowiak RSJ, Mazziotta JC, Evans AC (1994) Assessing the significance of focal activations using their spatial extent. Hum Brain Mapp 1:214-220
38. Carlesimo GA, Marfia GA, Loasses A, Caltagirone C (1996) Recency effect in anterograde amnesia: evidence for distinct memory stores underlying enhanced retrieval of terminal items in immediate and delayed recall paradigms. Neuropsychologia 34:177-184
39. Braak H, Braak E (1998) Evolution of neuronal changes in the course of Alzheimer's disease. J Neural Transm Suppl 53:127-140
40. Pennanen C, Kivipelto M, Tuomainen S, Hartikainen P, Hanninen T, Laakso MP, Hallikainen M, Vanhanen M, Nissinen A, Helkala EL, Vainio P, Vanninen R, Partanen K, Soininen H (2004) Hippocampus and entorhinal cortex in mild cognitive impairment and early AD. Neurobiol Aging 25:303-310
41. Baron JC, Chetelat G, Desgranges B, Perchey G, Landeau B, de la Sayette V, Eustache F (2001) In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer's disease. Neuroimage 14:298-309
42. Rombouts SA, Barkhof F, Witter MP, Scheltens P (2000) Unbiased wholebrain analysis of gray matter loss in Alzheimer's disease. Neurosci Lett 285:231-233
43. Ohnishi T, Matsuda H, Tabira T, Asada T, Uno M (2001) Changes in brain morphology in Alzheimer disease and normal ageing: is Alzheimer disease an exaggerated aging process? Am J Neuroradiol 22:1680-1685
44. Mosconi L (2005) Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. Eur J Nucl Med Mol Imaging 32:486-510
45. Dik MG, Jonker C, Bouter LM, Geerlings MI, van Kamp GJ, Deeg DJ (2000) APOE-epsilon4 is associated with memory decline in cognitively impaired elderly. Neurology 54:1492-1497
46. Bretsky P, Guralnik JM, Launer L, Albert M, Seeman TE; MacArthur Studies of Successful Aging (2003) The role of APOE-epsilon4 in longitudinal cognitive decline:MacArthur Studies of Successful Aging. Neurology 60:1077-1081
47. Ye S, Huang Y, Mullendorff K, Dong L, Giedt G, Meng EC, Cohen FE, Kuntz ID, Weisgraber KH, Mahley RW (2005) Apolipoprotein (apo) E4 enhances amyloid β peptide production in cultured neuronal cells: ApoE structure as a potential therapeutic target. PNAS 102:18700-18705
48. Corbo RM, Scacchi R (1999) Apolipoprotein E (APOE) allele distribution in the world. Is APOE*4 a 'thrifty' allele? Ann Hum Genet 63:301-310
49. Ranganath C, Heller A, Cohen MX, Brozinsky CJ, Rissman J (2005) Functional connectivity with the hippocampus during successful memory formation. Hippocampus 15:997-1005
50. Jack CR Jr, Petersen RC, Xu YC, O'Brien PC, Smith GE, Ivnik RJ, Boeve BF, Waring SC, Tangalos EG, Kokmen E (1999) Prediction of AD with MRIbased hippocampal volume in mild cognitive impairment. Neurology 52:1397-1403
51. Riemenschneider M, Lautenschlager N, Wagenpfeil S, Diehl J, Drzezga A, Kurz A (2002) Cerebrospinal fluid tau and beta-amyloid 42 proteins identify Alzheimer disease in subjects with mild cognitive impairment. Arch Neurol 59:1729-1734
52. 123I]Iodoamphetamine SPECT in mild cognitive impairment: implications for a novel predictor of Alzheimer's disease. Am J Psychiatry 159:474-476
53. Modrego PJ (2006) Predictors of conversion to dementia of probable Alzheimer type in patients with mild cognitive impairment. Curr Alzheimer Res 3:161-170