O-desulfated heparin improves outcome after rat cerebral ischemia/reperfusion injury

Neurosurgery

Volumn 61, Issue 6, 2007, Pages 1297-1303

  Mocco, J ^a,d   Shelton, Corbett E ^a   Sergot, Paulina ^a   Ducruet, Andrew F ^a   Komotar, Ricardo J ^a   Otten, Marc L ^a   Sosunov, Sergei A ^a   MacArthur, Robert B ^b   Kennedy, Thomas P ^c   Connolly, E Sander ^a  

^a Columbia University ^*  (United States)

^b Clinical Horizons Research Inc   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

Cerebral ischemia; Heparin; Inflammation; O desulfated heparin; Rat; Reperfusion injury

Indexed keywords

HEMOGLOBIN; HEPARIN; O DESULFATED HEPARIN; PHOSPHATE BUFFERED SALINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICOAGULATION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; AUTOPSY; BEDERSON SCALE; BLOOD CLOTTING TIME; BRAIN HEMORRHAGE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG STRUCTURE; FOOT FAULT TEST; HEART STROKE VOLUME; HEMOGLOBIN DETERMINATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROLOGIC EXAMINATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; STATISTICAL ANALYSIS; WISTAR RAT;

ANIMALS; CEREBRAL INFARCTION; DISEASE MODELS, ANIMAL; FREE RADICAL SCAVENGERS; HEPARIN; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; RATS; RATS, WISTAR; REPERFUSION INJURY; SEVERITY OF ILLNESS INDEX; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 37649000000     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.neu.0000306109.55174.e6     Document Type: Article

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