Heparin and nonanticoagulant heparin preserve regional myocardial contractility after ischemia-reperfusion injury: Role of nitric oxide

Journal of Thoracic and Cardiovascular Surgery

Volumn 115, Issue 2, 1998, Pages 440-449

  Kouretas, P C ^a   Myers, A K ^a   Kim, Y D ^a   Cahill, P A ^a   Myers, J L ^a   Wang Y , N ^a   Sitzmann, J V ^a   Wallace, R B ^a   Hannan, R L ^a   Del Nido, P J ^a   Sellke, F W ^a   Mayer J E , Jr ^a   Buxton, B ^a   Verrier, E D ^a   Hirsch, G M ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICOAGULATION; ARTICLE; CONTROLLED STUDY; HEART INFARCTION; HEART MUSCLE CONTRACTILITY; HEPARINIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY;

EID: 17944395799     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5223(98)70288-0     Document Type: Article

References (30)

1. YD Kim JS Fomsgaard KF Heim PW Ramwell G Thomas E Kagan Brief ischemia-reperfusion induces stunning of endothelium in canine coronary artery Circulation 85 1992 1473 1482
2. ST Summers MJ Zinner JA. Freischlag Production of endothelium-derived relaxing factor (EDRF) is compromised after ischemia and reperfusion Am J Surg 166 1993 216 220
3. WJ Paulus PJ Vantrimpont AM. Shah Paracrine coronary endothelial control of left ventricular function in humans Circulation 92 1995 2119 2126
4. P Mohan SU Sys DL. Brutsaert Positive inotropic effect of nitric oxide in myocardium Int J Cardiol 50 1995 233 237
5. N Hasebe YT Shen SF. Vatner Inhibition of endothelium-derived relaxing factor enhances myocardial stunning in conscious dogs Circulation 88 1993 2862 2871
6. MJ Saliba Jr JW Covell CM. Bloor Effects of heparin in large doses on the extent of myocardial ischemia after acute coronary occlusion in the dog Am J Cardiol 37 1976 599 604
7. K Yokokawa H Tahara M Kohno AK Mandal M Yanagisawa T. Takeda Heparin regulates endothelin production through endothelium-derived nitric oxide in human endothelial cells J Clin Invest 92 1993 2080 2085
8. SC Black MR Gralinski GS Friedrichs KS Kilgore EM Driscoll BR. Lucchesi Cardioprotective effects of heparin or N -acetyl heparin in an in vivo model of myocardial ischaemic and reperfusion injury Cardiovasc Res 29 1995 629 636
9. P Theroux D Franklin J Ross Jr WS. Kemper Regional myocardial function during acute coronary artery occlusion and its modification by pharmacologic agents in the dog Circ Res 35 1974 896 908
10. DJ Duncker RJ. Bache Inhibition of nitric oxide production aggravates myocardial hypoperfusion during exercise in the presence of a coronary artery stenosis Circ Res 74 1994 629 640
11. -15mole level Anal Biochem 70 1976 195 202
12. RD. Rosenberg The heparin-antithrombin system: a natural anticoagulant mechanism RW Colman J Hirsh VJ Marder EW Salzman Hemostasis and thrombosis: basic principles and clinical practice. 1987 JB Lippincott Philadelphia 1373 1392
13. FL Pasini AL Pasqui L Ceccetalli PL Capecchi A Orrico T. DiPerri Heparin inhibition of PMN activation in vitro: a possible pharmacological approach to granulocyte mediated vascular damage Thromb Res 35 1984 527 537
14. MD Kazatchkine DT Fearon DD Metcalfe RD Rosenberg KF. Austen Structural determinants of the capacity of heparin to inhibit the formation of the human amplification C3 convertase J Clin Invest 67 1981 223 228
15. RMJ Palmer AG Ferrige S. Moncada Nitric oxide release accounts for the biologic activity of endothelium-derived relaxing factor Nature 327 1987 524 526
16. RF. Furchgott Role of endothelium in responses of vascular smooth muscle Circ Res 53 1983 557 573
17. UC Garg A. Hassid Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells J Clin Invest 83 1989 1774 1777
18. DL Lawson JL Mehta WW. Nichols Coronary reperfusion in dogs inhibits endothelium-dependent relaxation: role of superoxide radicals Free Radic Biol Med 8 1990 373 380 1990
19. RJ Dignan CM Dyke AS Abd-Elfattah HA Lutz T Yeh Jr KF Lee Coronary artery endothelial cell and smooth muscle dysfunction after global myocardial ischemia Ann Thorac Surg 53 1992 311 317
20. AJ Brady JB Warren PA Poole-Wilson TJ Williams SE. Harding Nitric oxide attenuates cardiac myocyte contraction Am J Physiol 265 1993 H176 H182
21. MS Finkel CV Oddis OH Mayer BG Hattler RL. Simmons Nitric oxide synthase inhibitor alters papillary muscle force-frequency relationship J Pharmacol Exp Ther 272 1995 945 952
22. JM Hare E Loh MA Creager WS. Colucci Nitric oxide inhibits the positive inotropic response to β-adrenergic stimulation in humans with left ventricular dysfunction Circulation 92 1995 2198 2203
23. P Mohan DL Brutsaert WJ Paulus SU. Sys Myocardial contractile response to nitric oxide and cGMP Circulation 93 1996 1223 1229
24. G Kojda K Kottenberg P Nix KD Schluter HM Piper E. Noack Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes Circ Res 78 1996 91 101
25. JL Balligand RA Kelly PA Marsden TW Smith T. Michel Control of cardiac muscle cell function by an endogenous nitric oxide signaling system Proc Natl Acad Sci U S A 90 1993 347 351
26. WC Sternbergh III RG Makhoul B. Adelman Nitric oxide–mediated, endothelium-dependent vasodilation is selectively attenuated in the postischemic extremity Surgery 114 1993 960 967
27. MR Siegfried J Erhardt T Rider XL Ma AM. Lefer Cardioprotection and attenuation of endothelial dysfunction by organic nitric oxide donors in myocardial ischemia-reperfusion J Pharmacol Exp Ther 260 1992 668 675
28. R Pabla AJ Buda DM Flynn SA Blesse AM Shin MJ Curtis Nitric oxide attenuates neutrophil-mediated myocardial contractile dysfunction after ischemia and reperfusion Circ Res 78 1996 65 72
29. R Engler JW. Covell Granulocytes cause reperfusion ventricular dysfunction after 15-minute ischemia in the dog Circ Res 61 1987 20 28
30. GS Friedrichs KS Kilgore PJ Manley MR Gralinski BR. Lucchesi Effects of heparin and N -acetyl heparin on ischemia/reperfusion-induced alterations in myocardial function in the rabbit isolated heart Circ Res 75 1994 701 710