Amphiphilic helical peptides containing two acridine moieties display picomolar affinity toward HIV-1 RRE and TAR

Angewandte Chemie - International Edition

Volumn 47, Issue 1, 2008, Pages 134-137

  Lee, Yeongran ^a   Hyun, Soonsil ^a   Kim, Hyun Jin ^a   Yu, Jaehoon ^a  

^a Seoul National University   (South Korea)

Author keywords

Acridine; Hairpin RNA; Intercalations; Peptides; RNA

Indexed keywords

ACRIDINE; HAIRPIN RNA;

HYDROGEN BONDS; INTERCALATION; RNA; SYNTHESIS (CHEMICAL);

PEPTIDES;

ACRIDINE DERIVATIVE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; PEPTIDE; RNA BINDING PROTEIN; SURFACTANT; TRANS ACTIVATION RESPONSIVE RNA BINDING PROTEIN; TRANS-ACTIVATION RESPONSIVE RNA-BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CHEMISTRY; DNA RESPONSIVE ELEMENT; DRUG EFFECT; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; SYNTHESIS; VIRUS REPLICATION;

ACRIDINES; ANTI-HIV AGENTS; HIV-1; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RESPONSE ELEMENTS; RNA-BINDING PROTEINS; SURFACE-ACTIVE AGENTS; VIRUS REPLICATION;

EID: 37549070706     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200703090     Document Type: Article

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