Pharmacokinetics of ivermectin in pregnant and nonpregnant sheep

Journal of Veterinary Pharmacology and Therapeutics

Volumn 31, Issue 1, 2008, Pages 71-76

  Perez R ^a   Palma, C ^a   Nunez M J ^a   Cox, J ^a   Arboix, M ^b  

^a UNIVERSITY OF CONCEPCIÓN   (Chile)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

IVERMECTIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; COMPUTER ANALYSIS; CONTROLLED STUDY; DERIVATIZATION; ESTRUS; FEMALE; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; SHEEP; SINGLE DRUG DOSE; THIRD TRIMESTER PREGNANCY;

ANIMALS; ANTIPARASITIC AGENTS; AREA UNDER CURVE; FEMALE; INJECTIONS, SUBCUTANEOUS; IVERMECTIN; PREGNANCY; PREGNANCY, ANIMAL; SHEEP;

OVIS ARIES;

EID: 37549068938     PISSN: 01407783     EISSN: 13652885     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2007.00926.x     Document Type: Article

References (35)

1. Alvinerie, M., Sutra, J.F., Galtier, P. Toutain, P.L. (1993) Cinétiques plasmatiques de l'ivermectine chez la vache. Recueil de Medecine Veterinaire, 169, 259 261.
2. Alvinerie, M., Sutra, J.F., Badri, M. Galtier, P. (1995) Determination of moxidectin in plasma by high-performance liquid chromatography with automated solid-phase extraction and fluorescence detection. Journal of Chromatography, Series B, 674, 119 124.
3. Atta, A.H. Abo-Shihada, M.N. (2000) Comparative pharmacokinetics of doramectin and ivermectin in sheep. Journal of Veterinary Pharmacology and Therapeutics, 23, 49 52.
4. Barber, S., Bowles, V., Lespine, A. Alvinerie, M. (2003) The comparative serum kinetics of subcutaneous administration of doramectin, ivermectin and moxidectin in the Australian Merino sheep. Journal of Veterinary Pharmacology and Therapeutics, 26, 343 348.
5. Bassissi, M.F., Alvinerie, M. Lespine, A. (2004) Macrocyclic lactones: distribution in plasma lipoproteins of several animal species including humans. Comparative Biochemistry and Physiology, 138, 437 444.
6. Bogan, J. McKellar, Q.A. (1988) The pharmacodynamic of ivermectin in sheep. Journal of Veterinary Pharmacology and Therapeutics, 11, 260 268.
7. Campbell, W.C. Benz, G.W. (1984) Ivermectin: a review of efficacy and safety. Journal of Veterinary Pharmacology and Therapeutics, 7, 1 16.
8. Chamberlain, P.L., Fowler, B.A., Sexton, M.J., Peggins, J.O. von Bredow, J. (2003) Preliminary studies of offpring exposure to phenylbutazone and ivermectin during the perinatal period in the Holstein cow-calf model. Toxicology and Applied Pharmacology, 187, 198 208.
9. Chiu, S.L., Green, M.L., Baylis, F.P., Eline, D., Meriwether, H. Jacob, T.A. (1990) Absorption, tissue distribution and excretion of tritium-labeled ivermectin in cattle, sheep and rat. Journal of Agricultural and Food Chemistry, 38, 2072 2078.
10. Craven, J., Bjorn, H., Hennessy, D. Friis, C. (2002) The effect of body composition on the pharmacokinetics of subcutaneously injected ivermectin and moxidectin in pigs. Journal of Veterinary Pharmacology and Therapeutics, 25, 227 232.
11. De Montigny, P., Shim, J.S.K. Pivinichny, J.V. (1990) Liquid chromatographic determination of ivermectin in animal plasma with trifluoroacetic anhydride and N-methylimidazole as the derivatization reagent. Journal of Pharmaceutical and Biomedical Analysis, 8, 507 511.
12. Farrier, D. (1997) PK Solutions. Non-Compartmental Pharmacokinetics Data Analysis. User Guide. p. 50. Summit Research Services, Ashland, OH.
13. Frederiksen, M.C. (2001) Physiologic changes in pregnancy and their effect on drug disposition. Seminars in Perinatology, 25, 120 123.
14. Geary, T.G., Sims, S.M., Thomas, E.M., Vanover, L., Davis, J.P., Winterrowd, C.A., Klein, R.D., Ho, N.F.H. Thompson, D.P. (1993) Haemonchus contortus: ivermectin-induced paralysis of the pharynx. Experimental Parasitology, 77, 88 96.
15. Grimshaw, W.T.R., Hong, C. Hunt, K.R. (1997) Persistent activity of injectable ivermectin against important gastrointestinal nematodes of sheep. Veterinary Record, 141, 422 424.
16. Hennessy, D.R. Alvinerie, M.R. (2002) Pharmacokinetics of the macrocyclic lactones: conventional wisdom and new paradigm. In Macrocyclic Lactones in Antiparasitic Therapy, Chapter 2. Eds Vercruyss, E.J. Rew, R.S., pp. 97 123. CAB International, Wallingford.
17. Kumar, S., Tonn, G., Riggs, W. Rurak, D.W. (2000) Diphenhydramine disposition in the sheep maternal-placental-fetal unit: gestational age, plasma drug protein binding and umbilical blood flow effects on clearance. Drug Metabolism and Disposition, 28, 279 285.
18. Lanusse, C. (2003) Comparative pharmacokinetics of anthelmintic drugs in ruminants - updated integration of current knowledge. Journal of Veterinary Pharmacology and Therapeutics, 26 (Suppl. 1 42 47.
19. Lifschitz, A., Virkel, G., Pis, A., Imperiale, F., Sanchez, S., Alvarez, L., Kujanek, R. Lanusse, C. (1999) Ivermectin disposition kinetics after subcutaneous and intramuscular administration of an oil-based formulation to cattle. Veterinary Parasitology, 86, 203 2015.
20. Lifschitz, A., Virkel, G., Sutra, J.F., Galtier, P., Alvinerie, M. Lanusse, C. (2000) Comparative distribution of ivermectin and doramectin to parasite location tissues in cattle. Veterinary Parasitology, 87, 327 338.
21. Little, B.B. (1999) Pharmacokinetics during pregnancy: evidence based maternal dose formulation. Obstetrics and Gynecology, 43, 858 868.
22. Lo, P.A., Fink, D.W., Williams, J.B. Blodinger, J. (1985) Pharmacokinetic studies of ivermectin: effects of formulation. Veterinary Research Communications, 9, 251 268.
23. Mardones, F., Salazar, G., Rosso, P. Villarroel, L. (1998) Maternal body composition near term and birth weight. Obstetrics and Gynecology, 91, 183 187.
24. Marriner, S.E., McKinnon, Y. Bogan, J.A. (1987) The pharmacokinetics of ivermectin after oral and subcutaneous administration to sheep and horses. Journal of Veterinary Pharmacology and Therapeutics, 10, 175 179.
25. McKellar, Q.A. Benchaoui, H.A. (1996) Avermectins and milbemycins. Journal of Veterinary Pharmacology and Therapeutics, 19, 331 351.
26. McKellar, Q.A., Marriner, S.E. Bogan, J.A. (1988) Comparison of ivermectin, oxfendazole and levamisole for use as anthelmintics during the periparturient period in sheep. Veterinary Record, 122, 558 560.
27. Meyer, D., Coles, E. Rich, L. (1992) Veterinary Laboratory Medicine. Interpretation and Diagnosis, pp. 331. W.B. Saunders, Philadelphia, PA.
28. Nowakowski, M., Lynch, M., Smith, D., Logan, N., Mouzin, D., Lukaszewicz, J., Ryan, N., Hunter, R. Jones, R. (1995) Pharmacokinetics and bioequivalence of parenterally administered doramectin in cattle. Journal of Veterinary Pharmacology and Therapeutics, 18, 290 298.
29. Pérez, R., Palma, C., Cabezas, I., Araneda, M., Rubilar, L. Alvinerie, M. (2006) Effect of parasitism on the pharmacokinetic disposition of ivermectin in lambs. The Journal of Veterinary Medicine, 53, 43 48.
30. Prichard, R.K., Steel, J.W., Lacey, E. Hennessy, D. (1985) Pharmacokinetics of ivermectin in sheep following intravenous, intra-abomasal or intraruminal administration. Journal of Veterinary Pharmacology and Therapeutics, 8, 88 94.
31. Riviere, J.E. (1999) Comparative Pharmacokinetics: Principles, Techniques and Applications, pp. 148-167. Iowa State University Press, Ames, IA.
32. Santos, A.C., Arthur, G.R., Lehning, E.J. Finster, M. (1997) Comparative pharmacokinetics of ropivacaine and bupivacaine in nonpregnant and pregnant ewes. Anesthesia and Analgesia, 85, 87 93.
33. Shiverick, K.I., Slikker, W., Rogerson, S.J. Miller, K. (2003) Drugs and the placenta: a workshop. Placenta, 24 (Suppl. A 555 559.
34. Sklavounos, C., Dmers, N., Lukaszewicks, J. Nowakowski, M. (1994) Photoisomerization of aromatic doramectin derivatives. Journal of Agricultural and Food Chemistry, 42, 1228 1231.
35. Zajac, A.M., Thathcher, C.D., Brock, R.A., Umberger, S.H. Notter, D.R. (1992) Comparison of ivermectin formulations in an ovine parasite control program. Veterinary Record, 130, 353 354.