Investigation of serrated roll surface differences on ribbon thickness during roller compaction

Pharmaceutical Development and Technology

Volumn 12, Issue 6, 2007, Pages 603-608

  Daugherity, Patrick D ^a   Chu, Jennifer H ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Concavo convex rolls; Ribbon thickness; Roll serrations; Roller compaction; TF mini

Indexed keywords

APPARATUS, EQUIPMENT AND SUPPLIES; ARTICLE; CORRELATION ANALYSIS; MEASUREMENT; PRIORITY JOURNAL; RIBBON THICKNESS; ROLLER COMPACTOR; SURFACE PROPERTY; THICKNESS;

POWDERS; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 37549057004     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.1080/10837450701563012     Document Type: Article

References (17)

1. Tousey, M.D. The granulation process 101: Basic technologies for tablet making. Pharm. Technol. 2002, 26 (10), 8-13.
2. Iveson, S.M.; Litster, J.D.; Hapgood, K.; Ennis, B.J. Nucleation, growth and breakage phenomena in agitated wet granulation process: A review. Powder Technol. 2001, 117, 3-39.
3. Leuenberger, H. New trends in the production of pharmaceutical granules: The classical batch concept and the problem of scale-up. Eur. J. Pharm. Biopharm. 2001, 52, 279-288.
4. Miller, R.W.; Sheskey, P.J. Roller compaction techology for the pharmaceutical industry. In Encyclopedia of Pharmaceutical Technology; 2nd Ed.; Swarbrick, J., Boylan, J.C., Eds.; Marcel Dekker, Inc.: New York, 2003, 1:1-19.
5. Miller, R.W. Roller compaction technology. In Handbook of Pharmaceutical Granulation Technology; Parikh, D.M., Ed.; Marcel Dekker, Inc.: New York, 1997, 81:99-150.
6. Adeyeye, M.C. Roller compaction and milling pharmaceutical unit processes: Part I. Am. Pharm. Rev. 2000, 3 (4), 37-42.
7. Skinner, G.W.; Harcum, W.W.; Barnum, P.E.; Guo, J.H. The evaluation of fine-particle hydroxypropylcellulose as a roller compaction binder in pharmaceutical applications. Drug Dev. Ind. Pharm. 1999, 25 (10), 1121-1128.
8. Parrott, E.L. Densification of powders by concavo-convex roller compactor. J. Pharm. Sci. 1981, 70 (3), 288-291.
9. Inghelbrecht, S.; Remon, J.P. Roller compaction and tableting of microcrystalline cellulose/drug mixtures. Int. J. Pharm. 1998, 161, 215-224.
10. Falzone, A.M.; Peck, G.E.; McCabe, G.P. Effects of changes in roller compactor parameters on granulations produced by compaction. Drug Dev. Ind. Pharm. 1992, 18 (4), 469-489.
11. von Eggelkraut-Gottanka, S.G.; Abed, S.A.; Müller, W.; Schmidt, P.C. Roller compaction and tableting of St. John's wort plant dry extract using a gap width and force controlled roller compactor. I. Granulation and tableting of eight different extract batches. Pharm. Dev. Technol. 2002, 7 (4), 433-445.
12. DeYampert Rogers, T.L. Content considerations for low dosage drug formulations processed by roller compaction. Ph.D. thesis. Purdue University: West Lafayette, IN, USA, 1997.
13. Greaves, F.C.; Beasley, M.W.; Suddith, A.W.; Swarbrick, J. Novel approaches to the preparation of low-dose solid dosage forms. Pharm. Technol. 1995, 19 (1), 60-64.
14. Miller, R.W.; Sheskey, P.J. A survey of current industrial practices and preferences of roller compaction technology and excipients year 2000. Am. Pharm. Rev. 2001, 4 (1), 24-35.
15. Dehont, F.R.; Hervieu, P.M.; Jerome, E.; Delacourte, A.; Guyot, J.C. Briquetting and granulation by compaction: A new granulator-compactor. In Pharmaceutical Technology, Tableting Technology; Wells, J., Rubinstein, M., Eds.; Elis Horwood: London, 1993, 2 (Compression):1-11.
16. Johanson, J.R. Rolling theory for granular solids. Trans. Am. Soc. Mech. Eng. 1965, 842-848.
17. Sheskey, P.J.; Hendren, J. The effects of roll compaction equipment variables, granulation technique, and HPMC polymer level on a controlled-release matrix model drug formulation. Pharm. Technol. 1999, 23 (3), 90-106.