Heterochromatin density in the course of cell "dedifferentiation" represented by blastic transformation of human mature T lymphocytes

Journal of Applied Biomedicine

Volumn 5, Issue 4, 2007, Pages 189-193

  Smetana, Karel ^a   Otevřelová, Petra ^a   Kalousek, Ivan ^a  

^a INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION   (Czech Republic)

Author keywords

Blastic transformation; Heterochromatin density; Lymphocytes

Indexed keywords

DNA; PHYTOHEMAGGLUTININ;

APOPTOSIS; ARTICLE; B LYMPHOCYTE; BLAST TRANSFORMATION; CELL DIFFERENTIATION; CELL MATURATION; CELL NUCLEUS; CELL NUCLEUS MEMBRANE; COMPUTER ANALYSIS; CONTROLLED STUDY; CYTOCHEMISTRY; DENSITOMETRY; DENSITY; ERYTHROID PRECURSOR CELL; GENE SILENCING; GRANULOCYTE; HETEROCHROMATIN; HUMAN; HUMAN CELL; LEUKEMIA CELL; MYELOBLAST; NORMAL HUMAN; REPLICON; T LYMPHOCYTE;

EID: 37549055050     PISSN: 1214021X     EISSN: 12140287     Source Type: Journal    
DOI: 10.32725/jab.2007.025     Document Type: Article

References (24)

1. Astaldi G, Lisiewicz J: Lymphocytes. Idelson, Naples 1971.
2. Böyum A: Separation of leukocytes from blood and bone marrow. Scand. J. Clin. Lab. Invest. 21:9-109, 1968.
3. Busch H, Smetana K: The Nucleolus. Academic Press, New York 1970.
4. Carson DA: Biochemistry and function of lymphocytes and plasma cells. In Williams WJ, Beutler E, Erslev AJ, Lichtman MA (eds.): Hematology, McGraw-Hill, New York 1983, pp. 903-908.
5. Cline MJ: The White Cell. Harvard University Press, Cambridge 1975.
6. Comings DE: Arrangement of chromatin in the nucleus. Hum. Genet. 53:131-143, 1980.
7. Cremer T, Cremer C: Rise, fall and resurrection of chromosome territories: a historical perspective. Part III. Chromosome territories and the functional nuclear architecture: experiments and models from the 1990s to the present. Eur. J. Histochem. 50:223-272, 2006.
8. Frenster JH: Ultrastructure and function of heterochromatin and euchromatin. In Busch H (ed): The Cell Nucleus, Academic Press, New York 1974, pp. 565-581.
9. Grygoryev SA, Bulynko YA, Popova EY: The end adjusts the means: heterochromatin p remodeling during terminal cell differentiation. Chromosome Res. 14:53-69, 2006.
10. Hoffbrand AV, Pettit JE: Clinical Haematology. Gower Medical Publishing, London 1988.
11. Kalousek I, Križková P: Lymphocyte mitogenic transformation is accompanied by phosphorylation of the nucleolar transcription factor UBF. Cell Mol. Biol. (Noisy-le-grand), 46:1163-1171, 2000.
12. Monge JM, Val-Bernal JF, Buelta L, Garcia-Castrillo L, Asensio L: Selective nuclear morphometry as prognostic factor of survival of renal carcinoma. Histol. Histopathol. 14:119-123, 1999.
13. Nowell PC: Differentiation of human leukaemic leukocytes in tissue culture. Exp. Cell. Res. 19:267-277, 1960.
14. Ochs RL: Methods used to study structure and function of the nucleolus. Methods Cell Biol. 53:303-321, 1998.
15. Pederson T: The spatial organization of the genome in mammalian cells. Curr. Opin. Genet. Dev. 14:203-209, 2004.
16. Politi EN, Lazaris AC, Kavantzas A, Kountselini H: Comparison between morphometry and immunostaining of malignant cells in no-small cell lung cancer. Anal. Quant. Cytol. Histol. 25:169-176, 2003.
17. Rubin AD: Ribosome synthesis in cultured lymphocytes. II. The role of ribosomal RNA production in the initiation and maintenance of lymphocyte growth. Blood 35:708-720, 1970.
18. Setala L, Lipponen P, Kosma VM, Marin S, Eskelinen M, Syrjanen K, Alhava E: Nuclear morphometry as predictor of disease outcome in gastric cancer. J. Pathol. 181:46-50, 1977.
19. Schnedl W, Schnedl M: Nucleluszahl und grösse während des Zellzyklus. Z. Zellforsch. 126:374-382, 1972.
20. Smetana K: Nucleoli in maturing blood cells. Top. Rev. Haematol. 1:115-137, 1980.
21. Smetana K, Lejnar J, Potměšil M: A note to the demonstration of DNA in nuclei of blood cells in smear preparations. Folia Haematol. 88:305-317, 1967.
22. Smetana K, Lejnar J, Potměšil M: A further contribution to the demonstration of RNA and nucleoli of blood cells in smear preparations. Folia Haematol. 91:381-384, 1969.
23. Smetana K, Klamová H, Hrkal Z: To the density and distribution of condensed chromatin in differentiating maturing and apoptic cells represented by granulocytic, lymphoblastic and erythroblastic precursors in human bone marrow biopsies (a cytological study). Folia Biol. (Prague) 2007, in press.
24. Zhimulev IF: Heterochromatin, gene position effect and gene silencing. Genetika 39:187-201, 2003.