Diminished phagocytosis-induced cell death (PICD) in neonatal monocytes upon infection with Escherichia coli

Pediatric Research

Volumn 63, Issue 1, 2008, Pages 33-38

  Gille, Christian ^a   Leiber, Anja ^a   Spring, Bärbel ^a   Kempf, Volkhard A J ^a   Loeffler, Juergen ^b   Poets, Christian F ^a   Orlikowsky, Thorsten W ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; CASPASE 9; FAS ANTIGEN; FAS LIGAND; GREEN FLUORESCENT PROTEIN; LIPOCORTIN 5; MESSENGER RNA; REACTIVE OXYGEN METABOLITE;

ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; BACTERIAL INFECTION; CELL ACTIVITY; CELL COUNT; CHEMOLUMINESCENCE; CONTROLLED STUDY; DNA CONTENT; ESCHERICHIA COLI; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INFLAMMATION; MONOCYTE; NEWBORN; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHAGOCYTOSIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPSIS; STAINING; UMBILICAL CORD BLOOD;

ADULT; ANNEXIN A5; ANTIGENS, CD; APOPTOSIS; CASPASE 8; CASPASE 9; CELLS, CULTURED; DNA; ENZYME ACTIVATION; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FAS LIGAND PROTEIN; FETAL BLOOD; GREEN FLUORESCENT PROTEINS; HUMANS; INFANT, NEWBORN; MEMBRANE GLYCOPROTEINS; MONOCYTES; PHAGOCYTOSIS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TIME FACTORS;

EID: 37549050143     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/PDR.0b013e31815b8e9f     Document Type: Article

References (39)

1. Schrag SJ, Stoll BJ 2006 Early-onset neonatal sepsis in the era of widespread intrapartum chemoprophylaxis. Pediatr Infect Dis J 25:939-940
2. Hotchkiss RS, Nicholson DW 2006 Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol 6:813-822
3. Toti P, De Felice C, Occhini R, Schuerfeld K, Stumpo M, Epistolato MC, Vatti R, Buonocore G 2004 Spleen depletion in neonatal sepsis and chorioamnionitis. Am J Clin Pathol 122:765-771
4. Doughty L, Clark RS, Kaplan SS, Sasser H, Carcillo J 2002 sFas and sFas ligand and pediatric sepsis-induced multiple organ failure syndrome. Pediatr Res 52:922-927
5. Hotchkiss RS, Swanson PE, Freeman BD, Tinsley KW, Cobb JP, Matuschak GM, Buchman TG, Karl IE 1999 Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Crit Care Med 27:1230-1251
6. Hotchkiss RS, Tinsley KW, Swanson PE, Grayson MH, Osborne DF, Wagner TH, Cobb JP, Coopersmith C, Karl IE 2002 Depletion of dendritic cells, but not macrophages, in patients with sepsis. J Immunol 168:2493-2500
7. Hotchkiss RS, Tinsley KW, Swanson PE, Schmieg RE, Jr. Hui JJ, Chang KC, Osborne DF, Freeman BD, Cobb JP, Buchman TG, Karl IE 2001 Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans. J Immunol 166:6952-6963
8. Giamarellos-Bourboulis EJ, Routsi C, Plachouras D, Markaki V, Raftogiannis M, Zervakis D, Koussoulas V, Orfanos S, Kotanidou A, Armaganidis A, Roussos C, Giamarellou H 2006 Early apoptosis of blood monocytes in the septic host: is it a mechanism of protection in the event of septic shock? Crit Care 10:R76
9. Moraes TJ, Downey GP 2006 Death of the septic monocyte: is more better? Crit Care 10:146
10. DeLeo FR 2004 Modulation of phagocyte apoptosis by bacterial pathogens. Apoptosis 9:399-413
11. Zhang B, Hirahashi J, Cullere X, Mayadas TN 2003 Elucidation of molecular events leading to neutrophil apoptosis following phagocytosis. J Biol Chem 278:28443-28454
12. Skrzeczynska J, Kobylarz K, Hartwich Z, Zembala M, Pryjma J 2002 CD14+ CD16+ monocytes in the course of sepsis in neonates and small children: monitoring and functional studies. Scand J Immunol 55:629-638
13. Hanna N, Vasquez P, Pham P, Heck DE, Laskin JD, Laskin DL, Weinberger B 2005 Mechanisms underlying reduced apoptosis in neonatal neutrophils. Pediatr Res 57:56-62
14. Koenig JM, Stegner JJ, Schmeck AC, Saxonhouse MA, Kenigsberg LE 2005 Neonatal neutrophils with prolonged survival exhibit enhanced inflammatory and cytotoxic responsiveness. Pediatr Res 57:424-429
15. Gille C, Spring B, Tewes L, Poets CF, Orlikowsky T 2006 A new method to quantify phagocytosis and intracellular degradation using green fluorescent protein-labeled Escherichia coli: comparison of cord blood macrophages and peripheral blood macrophages of healthy adults. Cytometry A 69:152-154
16. Dehio M, Knorre A, Lanz C, Dehio C 1998 Construction of versatile high-level expression vectors for Bartonella henselae and the use of green fluorescent protein as a new expression marker. Gene 215:223-229
17. Gille C, Spring B, Bernhard W, Gebhard C, Basile D, Lauber K, Poets CF, Orlikowsky TW 2007 Differential effect of surfactant and its saturated phosphatidylcholines on human blood macrophages. J Lipid Res 48:307-317
18. Gerber CE, Kuci S, Zipfel M, Niethammer D, Bruchelt G 1996 Phagocytic activity and oxidative burst of granulocytes in persons with myeloperoxidase deficiency. Eur J Clin Chem Clin Biochem 34:901-908
19. Brown SB, Savill J 1999 Phagocytosis triggers macrophage release of Fas ligand and induces apoptosis of bystander leukocytes. J Immunol 162:480-485
20. Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C 1991 A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 139:271-279
21. Loeffler J, Bauer R, Hebart H, Douek DC, Rauser G, Bader P, Einsele H 2002 Quantification of T-cell receptor excision circle DNA using fluorescence resonance energy transfer and the LightCycler system. J Immunol Methods 271:167-175
22. Speer CP, Ambruso DR, Grimsley J, Johnston RB Jr 1985 Oxidative metabolism in cord blood monocytes and monocyte-derived macrophages. Infect Immun 50:919-921
23. Baran J, Weglarczyk K, Mysiak M, Guzik K, Ernst M, Flad HD, Pryjma J 2001 Fas (CD95)-Fas ligand interactions are responsible for monocyte apoptosis occurring as a result of phagocytosis and killing of Staphylococcus aureus. Infect Immun 69:1287-1297
24. Hacker H, Furmann C, Wagner H, Hacker G 2002 Caspase-9/-3 activation and apoptosis are induced in mouse macrophages upon ingestion and digestion of Escherichia coli bacteria. J Immunol 169:3172-3179
25. Yamaki K, Hong J, Hiraizumi K, Ahn JW, Zee O, Ohuchi K 2002 Participation of various kinases in staurosporine induced apoptosis of RAW 264.7 cells. J Pharm Pharmacol 54:1535-1544
26. Pirnia F, Schneider E, Betticher DC, Borner MM 2002 Mitomycin C induces apoptosis and caspase-8 and -9 processing through a caspase-3 and Fas-independent pathway. Cell Death Differ 9:905-914
27. Kang YH, Lee KA, Ryu CJ, Lee HG, Lim JS, Park SN, Paik SG, Yoon DY 2006 Mitomycin C induces apoptosis via Fas/FasL dependent pathway and suppression of IL-18 in cervical carcinoma cells. Cancer Lett 237:33-44
28. Allgaier B, Shi M, Luo D, Koenig JM 1998 Spontaneous and Fas-mediated apoptosis are diminished in umbilical cord blood neutrophils compared with adult neutrophils. J Leukoc Biol 64:331-336
29. Weglarczyk K, Baran J, Zembala M, Pryjma J 2004 Caspase-8 activation precedes alterations of mitochondrial membrane potential during monocyte apoptosis induced by phagocytosis and killing of Staphylococcus aureus. Infect Immun 72:2590-2597
30. Drenou B, Choqueux C, El Ghalbzouri A, Blancheteau V, Toubert A, Charron D, Mooney N 1998 Characterisation of the roles of CD95 and CD95 ligand in cord blood. Bone Marrow Transplant 22:S44-S47
31. Orlikowsky TW, Spring B, Dannecker GE, Niethammer D, Poets CF, Hoffmann MK 2003 Expression and regulation of B7 family molecules on macrophages (MPhi) in preterm and term neonatal cord blood and peripheral blood of adults. Cytometry B Clin Cytom 53:40-47
32. Orlikowsky TW, Dannecker GE, Spring B, Eichner M, Hoffmann MK, Poets CF 2005 Effect of dexamethasone on B7 regulation and T cell activation in neonates and adults. Pediatr Res 57:656-661
33. Forster-Waldl E, Sadeghi K, Tamandl D, Gerhold B, Hallwirth U, Rohrmeister K, Hayde M, Prusa AR, Herkner K, Boltz-Nitulescu G, Pollak A, Spittler A 2005 Monocyte toll-like receptor 4 expression and LPS-induced cytokine production increase during gestational aging. Pediatr Res 58:121-124
34. Viemann D, Dubbel G, Schleifenbaum S, Harms E, Sorg C, Roth J 2005 Expression of toll-like receptors in neonatal sepsis. Pediatr Res 58:654-659
35. Sadeghi K, Berger A, Langgartner M, Prusa AR, Hayde M, Herkner K, Pollak A, Spittler A, Forster-Waldl E 2007 Immaturity of infection control in preterm and term newborns is associated with impaired toll-like receptor signaling. J Infect Dis 195:296-302
36. Taylor S, Bryson YJ 1985 Impaired production of gamma-interferon by newborn cells in vitro is due to a functionally immature macrophage. J Immunol 134:1493-1497
37. Schultz C, Rott C, Temming P, Schlenke P, Moller JC, Bucsky P 2002 Enhanced interleukin-6 and interleukin-8 synthesis in term and preterm infants. Pediatr Res 51:317-322
38. Gille C, Spring B, Tewes LJ, Loffler J, Dannecker GE, Hoffmann MK, Eichner M, Poets CF, Orlikowsky TW 2006 Diminished response to interleukin-10 and reduced antibody-dependent cellular cytotoxicity of cord blood monocyte-derived macrophages. Pediatr Res 60:152-157
39. Dammann O, Leviton A 2006 Inflammation, brain damage and visual dysfunction in preterm infants. Semin Fetal Neonatal Med 11:363-368