Characterization of the induced neuropeptide Y-like immunoreactivity in primary sensory neurons following complete median nerve transection

Journal of Neurotrauma

Volumn 24, Issue 12, 2007, Pages 1878-1888

  Tsai, Yi Ju ^a   Lin, Chi Te ^b   Lue, June Horng ^b  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Cuneate nucleus; Dorsal rhizotomy; DRG neuron; Fluorogold; Fluororuby; Neuropeptide Y; Transected median nerve

Indexed keywords

FLUORESCENT DYE; FLUOROGOLD; NEUROPEPTIDE Y;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL LABELING; CONTROLLED STUDY; CUNEATE NUCLEUS; DORSAL RHIZOTOMY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MEDIAN NERVE; NERVE CELL EXCITABILITY; NERVE INJURY; NERVE PROJECTION; NERVE TRANSECTION; NONHUMAN; RAT; SENSORY NERVE CELL; SPINAL GANGLION;

ANIMALS; AXOTOMY; FLUORESCENT DYES; GANGLIA, SPINAL; IMMUNOHISTOCHEMISTRY; MALE; MEDIAN NERVE; MEDULLA OBLONGATA; NEURAL PATHWAYS; NEURONS, AFFERENT; NEUROPEPTIDE Y; PAIN; RATS; RATS, WISTAR;

EID: 37549040588     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2007.3488     Document Type: Article

References (38)

1. Abdulla, F.A., and Smith, P.A. (1999). Nerve injury increases an excitatory action of neuropeptide Y and Y2-agonists on dorsal root ganglion neurons. Neuroscience 89, 43-60.
2. Baron, R., Janig, W., and With, H. (1995). Sympathetic and afferent neurones projecting into forelimb and trunk nerves and the anatomical organization of the thoracic sympathetic outflow of the rat. J. Auton. Nerv. Syst. 53, 205-214.
3. Bennett, G.J. (1993). An animal model of neuropathic pain: a review. Muscle Nerve 16, 1040-1048.
4. Coderre, T.J., Grimes, R.W., and Melzack, R. (1986). Deafferentation and chronic pain in animals: an evaluation of evidence suggesting autotomy is related to pain. Pain 26, 61-84.
5. Colvin, L.A., and Duggan, A.W. (2001). The effect of conduction block on the spinal release of immunoreactive-neuropeptide Y (ir-NPY) in the neuropathic rat. Pain 91, 235-240.
6. Cravioto, H., and Battista, A. (1981). Clinical and ultrastructural study of painful neuroma. Neurosurgery 8, 181-190.
7. Day, A.S., Lue, J.H., Sun, W.Z., Shieh, J.Y., and Wen, C.Y. (2001a). A - fiber intensity stimulation of chronically constricted median nerve induces c-fos expression in thalamic projection neurons of the cuneate nucleus in rats with behavioral signs of neuropathic pain. Brain Res. 895, 194-203.
8. Day, A.S., Wen, C.Y., Shieh, J.Y., Sun, W.Z., and Lue, J.H. (2001b). Somatic noxious mechanical stimulation induces Fos expression in the postsynaptic dorsal column neurons in laminae III and IV of the rat spinal dorsal horn. Neurosci. Res. 40, 343-350.
9. Fried, K., Brodin, E., and Theodorsson, E. (1989). Substance P-, CGRPand NPY-immunoreactive nerve fibers in rat sciatic nerve-end neuromas. Regul. Pept. 25, 11-24.
10. Frisén, J., Risling, M., Theodorsson, E., and Fried, K. (1992). NPY-like immunoreactivity in sensory nerve fibers in rat sciatic neuroma. Brain Res. 577, 142-146.
11. González-Hernández, T., and Rustioni, A. (1999). Nitric oxide synthase and growth-associated protein are coexpressed in primary sensory neurons after peripheral injury. J. Comp. Neurol. 404, 64-74.
12. Landry, M., Holmberg, K., Zhang, X., and Hökfelt, T. (2000). Effect of axotomy on expression of NPY, galanin, and NPY Y1 and Y2 receptors in dorsal root ganglia and the superior cervical ganglion studied with double-labeling in situ hybridization and immunohistochemistry. Exp. Neurol. 162, 361-384.
13. Lue, J.H., Shieh, J.Y., Chen, K.N., and Wen, C.Y. (1993). Synaptic relationships between GABA-immunoreactive boutons and primary afferent terminals in the rat cuneate nucleus. Neuroscience 56, 973-979.
14. Lue, J.H., Jiang-Shieh, Y.F., Shieh, J.Y., Ling, E.A., and Wen, C.Y. (1997). Multiple inputs of GABA-immunoreactive neurons in the cuneate nucleus of the rat. Neurosci. Res. 27, 123-132.
15. Lue, J.H., Leong, S.M., Day, A.S., Tsai, Y.J., Shieh, J.Y., and Wen, C.Y. (2002). Changes in c-fos protein expression in the rat cuneate nucleus after electric stimulation of the transected median nerve. J. Neurotrauma 19, 897-907.
16. Lundberg, J.M., Terenius, L., Hökfelt, T., and Goldstein, M. (1983). High levels of neuropeptide Y in peripheral noradrenergic neurons in various mammals including man. Neurosci. Lett. 42, 167-172.
17. Ma, W., and Bisby, M.A. (1997). Differential expression of galanin immunoreactivities in the primary sensory neurons following partial and complete sciatic nerve injuries. Neuroscience 79, 1183-1195.
18. Ma, W., and Bisby, M.A. (1998). Partial and complete sciatic nerve injuries induce similar increases of neuropeptide Y and vasoactive intestinal peptide immunoreactivities in primary sensory neurons and their central projections. Neuroscience 86, 1217-1234.
19. Ma, W., and Bisby, M.A. (1999). Ultrastructural localization of increased neuropeptide immunoreactivity in the axons and cells of the gracile nucleus following chronic constriction injury of the sciatic nerve. Neuroscience 93, 335-348.
20. Ma, W., and Bisby, M.A. (2000). Partial sciatic nerve ligation induced more dramatic increase of neuropeptide Y immunoreactive axonal fibers in the gracile nucleus of middle-aged rats than in young adult rats. J. Neurosci. Res. 60, 520-530.
21. Miki, K., Fukuoka, T., Tokunaga, A., and Noguchi, K. (1998). Calcitonin gene-related peptide increase in the rat spinal dorsal horn and dorsal column nucleus following peripheral nerve injury: up-regulation in a subpopulation of primary afferent sensory neurons. Neuroscience 82, 1243-1252.
22. Noguchi, K., De Leon, M., Nahin, R.L., Senba, E., and Ruda, M.A. (1993). Quantification of axotomy-induced alteration of neuropeptide mRNAs in dorsal root ganglion neurons with special reference to neuropeptide Y mRNA and the effects of neonatal capsaicin treatment. J. Neurosci. Res. 35, 54-66.
23. Noguchi, K., Kawai, Y., Fukuoka, T., Senba, E., and Miki, K. (1995). Substance P induced by peripheral nerve injury in primary afferent sensory neurons and its effect on dorsal column nucleus neurons. J. Neurosci. 15, 7633-7643.
24. Nyberg, G., and Blomqvist, A. (1982). The termination of forelimb nerves in the feline cuneate nucleus demonstrated by the transganglionic transport method. Brain Res. 248, 209-222.
25. Ohara, S., Roth, K.A., Beaudet, L.N., and Schmidt, R.E. (1994). Transganglionic neuropeptide Y response to sciatic nerve injury in young and aged rats. J. Neuropathol. Exp. Neurol. 53, 646-662.
26. Ohara, S., Tantuwaya, V., Distefano, P.S., and Schmidt, R.E. (1995). Exogenous NT-3 mitigates the transganglionic neuropeptide Y response to sciatic nerve injury. Brain Res. 699, 143-148.
27. Ossipov, M.H., Zhang, E.T., Carvajal, C., Gardell, L., Quirion, R., Dumont, Y., Lai, J., et al. (2002). Selective mediation of nerve injury-induced tactile hypersensitivity by neuropeptide Y. J. Neurosci. 22, 9858-9867.
28. Persson, J.K.E., Lindh, B., Elde, R., Robertson, B., Rivero-Melian, C., Eriksson, N.P., Hökfelt, T., et al. (1995). The expression of different cytochemical markers in normal and axotomised dorsal root ganglion cells projecting to the nucleus gracilis in the adult rat. Exp. Brain Res. 105, 331-344.
29. Risling, M., Dalsgaard, C.J., and Terenius, L. (1985). Neuropeptide Y-like immunoreactivity in the lumbosacral pia mater in normal cats and after sciatic neuroma formation. Brain Res. 358, 372-375.
30. Sterne, G.D., Brown, R.A., Green, C.J., and Terenghi, G. (1998). NT-3 modulates NPY expression in primary sensory neurons following peripheral nerve injury. J. Anat. 193, 273-281.
31. Tracey, D.J., Romm, M.A., and Yao, N.N.L. (1995). Peripheral hyperalgesia in experimental neuropathy: exacerbation by neuropeptide Y. Brain Res. 669, 245-254.
32. Tsai, Y.J., Leong, S.M., Day, A.S., Wen, C.Y., Shieh, J.Y., and Lue, J.H. (2004). A time course analysis of the changes in neuropeptide Y immunoreactivity in the rat cuneate nucleus following median nerve transection. Neurosci. Res. 48, 369-377.
33. Wakisaka, S., Kajander, K.C., and Bennett, G.J. (1992). Effects of peripheral nerve injuries and tissue inflammation on the levels of neuropeptide Y-like immunoreactivity in rat primary afferent neurons. Brain Res. 598, 349-352.
34. Wakisaka, S., Takikita, S., Sasaki, Y., Kato, J., Tabata, M.J., and Kurisu, K. (1993). Cell size-specific appearance of neuropeptide Y in the trigeminal ganglion following peripheral axotomy of different branches of the mandibular nerve of the rat. Brain Res. 620, 347-350.
35. Wall, P.D., Scadding, J.W., and Tomkiewicz, M.M. (1979). The production and prevention of experimental anesthesia dolorosa. Pain 6, 175-182.
36. White, D.M. (1997). Intrathecal neuropeptide Y exacerbates nerve injury-induced mechanical hyperalgesia. Brain Res. 750, 141-146.
37. Zhang, X., Meister, B., Elde, R., Verge, V.M.K., and Hökfelt, T. (1993). Large calibre primary afferent neurons projecting to the gracile nucleus express neuropeptide Y after sciatic nerve lesions: an immunohistochemical and in situ hybridization study in rats. Eur. J. Neurosci. 5, 1510-1519.
38. Zochodne, D.W., Cheng, C., Miampamba, M., Hargreaves, K., and Sharkey, K.A. (2001). Peptide accumulations in proximal endbulbs of transected axons. Brain Res. 902, 40-50.