Intrathecal neuropeptide Y exacerbates nerve injury-induced mechanical hyperalgesia

Brain Research

Volumn 750, Issue 1-2, 1997, Pages 141-146

  White, Deborah M ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

trinositol; Leu31,Pro34 neuropeptide Y; hyperalgesia; N acetyl Leu28,Leu31 neuropeptide Y24 36; nerve injury; neuropeptide Y; nociceptive flexion reflex

Indexed keywords

INOSITOL 1,2,6 TRISPHOSPHATE; NEUROPEPTIDE Y; NEUROPEPTIDE Y DERIVATIVE; NEUROPEPTIDE Y RECEPTOR AGONIST; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FLEXOR REFLEX; HYPERALGESIA; INTRATHECAL DRUG ADMINISTRATION; MECHANICAL STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE;

ANALYSIS OF VARIANCE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; FUNCTIONAL LATERALITY; HYPERALGESIA; INJECTIONS, SPINAL; INOSITOL PHOSPHATES; NEUROPEPTIDE Y; PAIN; RATS; RATS, WISTAR; RECEPTORS, NEUROPEPTIDE Y; SCIATIC NERVE; SENSORY THRESHOLDS; SPINAL CORD;

EID: 0031052380     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01340-6     Document Type: Article

References (36)

1. Bennett, G.J. and Xie, Y.K., A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man, Pain, 33 (1988) 87-107.
2. 2 receptor, Br. J. Pharmacol., 103 (1991) 1781-1789.
3. De Quit, M.E. and Emson, P.C., Distribution of neuropeptide Y-like immunoreactivity in the rat central nervous system-II. Immunohistochemical analysis, Neuroscience, 18 (1986) 545-618.
4. 2-purinoceptor antagonists in rats, Brain Res., 666 (1994) 182-188.
5. Duggan, A.W., Hope, P.J. and Lang, C.W., Microinjection of neuropeptide Y into the superficial dorsal horn reduces stimulus-evoked release of immunoreactive substance P in the anaesthetized cat, Neuroscience, 44 (1991) 733-740.
6. Gibson, S.J., Polak, J.M., Allen, J.M., Adrian, T.E., Kelly, J.S. and Bloom, S.R., The distribution and origin of a novel brain peptide, neuropeptide Y, in the spinal cord of several mammals, J. Comp. Neurol., 227 (1984) 78-91.
7. Herzog, H., Hort, Y.J., Ball, H.J., Hayes, G., Shine, J. and Selbie, L.A., Cloned human neuropeptide Y receptor couples to two different second messenger systems, PNAS, 89 (1992) 5794-5798.
8. Hökfelt, T., Zhang, X. and Wiesenfeld-Hallin, Z., Messenger plasticity in primary sensory neurons following axotomy and its functional implications, TINS, 17 (1994) 22-29.
9. Hua, X-Y., Boublik, J.H., Spicer, M.A., Rivier, J.E., Brown, M.R. and Yaksh, T.L., The antinociceptive effects of spinally administered neuropeptide Y in the rat: systematic studies on structure-activity relationship, J. Pharmacol. Exp. Ther., 258 (1991) 243-248.
10. Jenkins, R., McMahon, S.B., Bond, A.B. and Hunt, S.P., Expression of cJUN as a response to dorsal root and peripheral nerve section in damaged and adjacent intact primary sensory neurons in the rat, Eur. J. Neurosci., 5 (1993) 751-759.
11. Mantyh, P.W., Allen, C.J., Rogers, S., DeMaster, E., Ghilardi, J.R., Mosconi, T., Kruger, L., Mannon, P.J., Taylor, I.L. and Vigna, S.R., Some sensory neurons express neuropeptide Y receptors: potential paracrine inhibition of primary afferent nociceptors following peripheral nerve injury, J. Neurosci., 14 (1994) 3958-3968.
12. Mc Quiston, A.R., Petrozzino, J.J., Connor, J.A. and Colmers, W.F., Neuropeptide Y1 receptors inhibit N-type calcium currents and reduce transient calcium increases in rat dentate granule cells, J. Neurosci., 16 (1996) 1422-1429.
13. Nahin, R.L., Ren, K., De Leon, M. and Ruda, M.A., Primary sensory neurons exhibit altered gene expression in a rat model of neuropathic pain, Pain, 58 (1994) 95-108.
14. Noguchi, K., De León, M., Nahin, R.L., Senba, E. and Ruda, M.A., Quantification of axotomy-induced alteration of neuropeptide mRNAs in dorsal root ganglion neurons with special reference to neuropeptide Y mRNA and the effects of neonatal capsaicin treatment, J. Neurosci. Res., 35 (1993) 54-66.
15. Randall, L.O. and Selitto, J.J., A method for the measurement of analgesic activity on inflamed tissue, Arch. Int. Pharmacodyn., 3 (1957) 409-419.
16. Rowan, S., Todd, A.J. and Spike, R.C., Evidence that neuropeptide Y is present in GABAergic neurons in the dorsal horn of the rat spinal cord, Neuroscience, 53 (1993) 537-545.
17. Salter, M.W., de Koninck, Y. and Henry, J.L., Physiological roles for adenosine and ATP in synaptic transmission in the spinal dorsal horn, Progr. Neurobiol., 41 (1993) 125-156.
18. Sasek, C.A. and Eide, R.P., Distribution of neuropeptide Y-like immunoreactivity and its relationship to FMRF-amide-like immunoreactivity in the sixth lumbar and first sacral spinal cord segments of the rat, J. Neurosci., 5 (1985) 1729-1739.
19. Seltzer, Z., Dubner, R. and Shir, Y., A novel behavioural model of neuropathic pain disorders produced in rats by partial sciatic nerve injury, Pain, 43 (1990) 205-218.
20. Shir, Y. and Seltzer, Z., A-fibers mediate touch-evoked allodynia and hyperesthesia and C-fibers mediate thermal hyperalgeisa in a rat model of sympathetically-maintained neuropathic pain, Neurosci. Lett., 115 (1990) 62-67.
21. Sun, X.Y., Edvinsson, L. and Hedner, T., Effects of d-myo-inositol-1,2,6-trisphosphate on neuropeptide Y-induced potentiation of various vasoconstrictor agents in the rat, J. Pharmacol. Exp. Therap. 261 (1992) 1147-1152.
22. Taiwo, Y.O., Coderre, T.J. and Levine, J.D., The contribution of training to sensitivity in the nociceptive paw-withdrawal test, Brain Res., 487 (1989) 148-151.
23. Tracey, D.J., Romm, M.A. and Yao, N.N.L., Peripheral hyperalgesia in experimental neuropathy: exacerbation by neuropeptide Y, Brain Res., 699 (1995) 245-254.
24. Wahlestedt, C., Reis, D.J., Yoo, H., Adamsson, M., Andersson, D. and Edvinsson, L., A novel inositol phosphate selectively inhibits vasoconstriction evoked by the sympathetic co-transmitters neuropeptide Y (NPY) and adenosine triphosphate (ATP), Neurosci. Lett., 143 (1992) 123-126.
25. Wahlestedt, C. and Reis, D.J., Neuropeptide Y-related peptides and their receptors - are the receptors potential therapeutic drug targets?, Annu. Rev. Pharmacol. Toxicol., 32 (1993) 309-352.
26. Wakisaka, S., Kajander, K.C. and Bennett, G.J., (1991) Increased neuropeptide Y (NPY)-like immunoreactivity in rat sensory neurons following peripheral axotomy, Neurosci. Lett., 124 (1991) 200-203.
27. 2+ currents in rat sensory neurons, J. Neurosci., 8 (1988) 2438-2446.
28. White, D.M. and Mansfield, K., Vasoactive intestinal polypeptide and neuropeptide Y act indirectly to increase neurite outgrowth of dissociated dorsal root ganglion cells, Neuroscience, 73 (1996) 881-887.
29. Wiley, J.W., Gross, R.A. and MacDonald, R.L., Agonists for neuropeptide Y receptor subtypes NPY-1 and NPY-2 have opposite actions on rat nodose neuron calcium currents, J. Neurophysiol., 70 (1993) 324-330.
30. Willis, W.D. and Coggeshall, R.E., Sensory Mechanisms of the Spinal Cord, Plenum, New York, NY, 1991.
31. Woolf, C.J., Shortland, P. and Coggeshall, R.E., Peripheral nerve injury triggers central sprouting of myelinated afferents, Nature (London), 355 (1992) 75-78.
32. Xu, X.U., Hao, J.-X., Hökfelt, T. and Wiesenfeld-Hallin, Z., The effects of intrathecal neuropeptide Y on the spinal nociceptive flexor reflex in rats with intact sciatic nerves and after peripheral axotomy, Neuroscience, 63 (1994) 817-826.
33. Yaksh, T.L. and Rudy, T.A., Chronic catheterization of the spinal subarachnoid space, Physiol. Behav., 17 (1976) 1031-1036.
34. 1 receptors in the rat nervous system with special reference to somatic receptors on small dorsal root ganglion neurons, Proc. Natl. Acad. Sci. USA, 91 (1994) 11738-11742.
35. Zhang, X., Bean, A.J., Wiesenfeld-Hallin, Z. and Hökfelt, T., Ultrastructural studies on peptides in the dorsal horn of the rat spinal cord-IV. Effects of peripheral axotomy with special reference to neuropeptide Y and vasoactive intestinal polypeptide/peptide histidine isoleucine, Neuroscience, 64 (1995) 917-941.
36. Zhang, X., Wiesenfeld-Hallin, Z. and Hökfelt, T., Effect of peripheral axotomy on expression of neuropeptide Y receptor mRNA in rat lumbar dorsal root ganglia, Eur. J. Neurosci., 6 (1994) 43-57.