Synthesis of furo[2,3-b]pyrazine nucleoside analogues with 1,2,3-triazole linkage

QSAR and Combinatorial Science

Volumn 26, Issue 11-12, 2007, Pages 1266-1273

  Ermolat'ev, Denis S ^a   Mehta, Vaibhav Pravinchandra ^a   Van Der Eycken, Erik V ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

1,2,3 Triazoles; 1,3 Dipolar cycloaddition; 2(1H) pyrazinone; Click chemistry; Furo 2,3 b pyrazines; Nucleoside analogues

Indexed keywords

BIOMOLECULES; CATALYSIS; CHEMICAL BONDS; COPPER COMPOUNDS; CYCLOADDITION;

1,2,3-TRIAZOLE; 1,3-DIPOLAR CYCLOADDITION; 2(1H)-PYRAZINONE; 3-DIPOLAR CYCLOADDITION; CLICK CHEMISTRY; D RIBOSE; FURO[2,3-B]PYRAZINE; NUCLEOSIDE ANALOGS; PYRAZINES; TRIAZOLE LINKAGES;

CYCLIZATION;

1 (4 METHOXYBENZYL) 3 [2 (4 TERT BUTYLPHENYL)ETHYNYL] 5 CHLOROPYRAZIN 2(1H)ONE; 1 (4 METHOXYBENZYL) 5 CHLORO 3 (2 4 TOLYLETHYNYL)PYRAZIN 2(1H)ONE; 1 (4 METHOXYBENZYL) 5 CHLORO 3 (CYCLOHEXYLETHYNYL) 6 METHYLPYRAZIN 2(1H)ONE; 1 (4 METHOXYBENZYL) 5 CHLORO 3 (HEPT 1 YNYL)PYRAZIN 2(1H)ONE; 1 (4 METHOXYBENZYL) 5 CHLORO 3 (HEX 1 YNYL) 6 METHYLPYRAZIN 2(1H)ONE; 1 (4 METHOXYBENZYL) 5 CHLORO 3 (PHENYLETHYNYL)PYRAZIN 2(1H)ONE; 1 (4 METHOXYBENZYL) 5 CHLORO 3 [(2 METHYLPHENYL)ETHYNYL]PYRAZIN 2(1H)ONE; 1 (4 METHOXYBENZYL) 5 CHLORO 3 [(4 ETHYLPHENYL)ETHYNYL] 6 (4 METHOXYPHENYL)PYRAZIN 2(1H)ONE; 1,2,3 TRIAZOLE DERIVATIVE; 2 CHLORO 3 METHYL 6 BUTYLFURO[2,3 B]PYRAZINE; 2 CHLORO 3 METHYL 6 CYCLOHEXYLFURO[2,3 B]PYRAZINE; 2 CHLORO 6 (2 METHYLPHENYL)FURO[2,3 B]PYRAZINE; 2 CHLORO 6 (4 ETHYLPHENYL) 3 (4 METHOXYPHENYL)FURO[2,3 B]PYRAZINE; 2 CHLORO 6 4 TOLYLFURO[2,3 B]PYRAZINE; 2 CHLORO 6 PENTYLFURO[2,3 B]PYRAZINE; 2 CHLORO 6 PHENYLFURO[2,3 B]PYRAZINE; 2 DEOXYRIBOSE; 6 (4 TERT BUTYLPHENYL) 2 CHLOROFURO[2,3 B]PYRAZINE; CUPROUS ION; NUCLEOSIDE ANALOG; PYRAZINE DERIVATIVE; RIBOSE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CROSS COUPLING REACTION; CYCLIZATION; CYCLOADDITION; PRIORITY JOURNAL; SONOGASHIRA REACTION; SYNTHESIS;

EID: 37549039786     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200740123     Document Type: Article

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