-
1
-
-
28744446111
-
Rapid and reversible chemical inactivation of synaptic transmission in genetically targeted neurons
-
This study demonstrates functionality of MISTs, non-conductance-based neuronal silencing tools, with application to studying cerebellar learning in vivo.
-
Karpova A.Y., Tervo D.G.R., Gray N.W., and Svoboda K. Rapid and reversible chemical inactivation of synaptic transmission in genetically targeted neurons. Neuron 48 (2005) 727-735. This study demonstrates functionality of MISTs, non-conductance-based neuronal silencing tools, with application to studying cerebellar learning in vivo.
-
(2005)
Neuron
, vol.48
, pp. 727-735
-
-
Karpova, A.Y.1
Tervo, D.G.R.2
Gray, N.W.3
Svoboda, K.4
-
2
-
-
33745880721
-
Selective and quickly reversible inactivation of mammalian neurons in vivo using the Drosophila allatostatin receptor
-
This study demonstrates the functionality of AlstR in a remarkable variety of animal models.
-
Tan E.M., Yamaguchi Y., Horwitz G.D., Gosgnach S., Lein E.S., Goulding M., Albright T.D., and Callaway E.M. Selective and quickly reversible inactivation of mammalian neurons in vivo using the Drosophila allatostatin receptor. Neuron 51 (2006) 157-170. This study demonstrates the functionality of AlstR in a remarkable variety of animal models.
-
(2006)
Neuron
, vol.51
, pp. 157-170
-
-
Tan, E.M.1
Yamaguchi, Y.2
Horwitz, G.D.3
Gosgnach, S.4
Lein, E.S.5
Goulding, M.6
Albright, T.D.7
Callaway, E.M.8
-
3
-
-
33947693328
-
Reversible silencing of neuronal excitability in behaving mice by a genetically targeted, ivermectin-gated Cl-channel
-
This study demonstrates the utility of GluCIa,b controlled by ivermectin for manipulating amphetamine-induced rotational behavior, a classic behavioral paradigm for Parkinson's disease models.
-
Lerchner W., Xiao C., Nashmi R., Slimko E.M., van Trigt L., Lester H.A., and Anderson D.J. Reversible silencing of neuronal excitability in behaving mice by a genetically targeted, ivermectin-gated Cl-channel. Neuron 54 (2007) 35-49. This study demonstrates the utility of GluCIa,b controlled by ivermectin for manipulating amphetamine-induced rotational behavior, a classic behavioral paradigm for Parkinson's disease models.
-
(2007)
Neuron
, vol.54
, pp. 35-49
-
-
Lerchner, W.1
Xiao, C.2
Nashmi, R.3
Slimko, E.M.4
van Trigt, L.5
Lester, H.A.6
Anderson, D.J.7
-
4
-
-
34347347075
-
From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors
-
This paper reports that engineered GABA-A receptors can be used to introduce susceptibility for chemical silencing.
-
Wulff P., Goetz T., Leppa E., Linden A.-M., Renzi M., Swinny J.D., Vekovischeva O.Y., Sieghart W., Somogyi P., Korpi E.R., et al. From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors. Nat Neurosci 10 (2007) 923-929. This paper reports that engineered GABA-A receptors can be used to introduce susceptibility for chemical silencing.
-
(2007)
Nat Neurosci
, vol.10
, pp. 923-929
-
-
Wulff, P.1
Goetz, T.2
Leppa, E.3
Linden, A.-M.4
Renzi, M.5
Swinny, J.D.6
Vekovischeva, O.Y.7
Sieghart, W.8
Somogyi, P.9
Korpi, E.R.10
-
5
-
-
34547133175
-
-
Aravanis AM, Wang LP, Zhang F, Meltzer LA, Mogri MZ, Schneider MB, Deisseroth K: An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology. J Neural Eng 2007 Sep, 4(3):S143-56 [Epub 2007 May 31]. This study demonstrates combined fiber optic and optogenetic methods to create an optical neural interface for controlling mammalian behavior.
-
-
-
-
6
-
-
34247222730
-
Multimodal fast optical interrogation of neural circuitry
-
This paper introduces fast, genetically-targeted, combined optical inhibition and excitation in intact mammalian brain tissue.
-
Zhang F., Wang L.-P., Brauner M., Liewald J.F., Kay K., Watzke N., Wood P.G., Bamberg E., Nagel G., Gottschalk A., et al. Multimodal fast optical interrogation of neural circuitry. Nature 446 (2007) 633-639. This paper introduces fast, genetically-targeted, combined optical inhibition and excitation in intact mammalian brain tissue.
-
(2007)
Nature
, vol.446
, pp. 633-639
-
-
Zhang, F.1
Wang, L.-P.2
Brauner, M.3
Liewald, J.F.4
Kay, K.5
Watzke, N.6
Wood, P.G.7
Bamberg, E.8
Nagel, G.9
Gottschalk, A.10
-
7
-
-
33749020262
-
Channelrhodopsin-2 and optical control of excitable cells
-
Zhang F., Wang L.-P., Boyden E.S., and Deisseroth K. Channelrhodopsin-2 and optical control of excitable cells. Nat Methods 3 (2006) 785-792
-
(2006)
Nat Methods
, vol.3
, pp. 785-792
-
-
Zhang, F.1
Wang, L.-P.2
Boyden, E.S.3
Deisseroth, K.4
-
8
-
-
36248996490
-
-
Adamantidis AR, Zhang F, Aravanis AM, Deisseroth K, de Lecea L: Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature 2007 Nov 15, 450(7168):420-4 [Epub 2007 Oct 17]. This study implements the optogenetic neural interface to control a specific class of neuropsychiatric disease-relevant neurons and determine resulting behavior, in freely moving mammals.
-
-
-
-
9
-
-
34248548818
-
Remote control of neuronal activity with a light-gated glutamate receptor
-
Szobota S., Gorostiza P., Del Bene F., Wyart C., Fortin D.L., Kolstad K.D., Tulyathan O., Volgraf M., Numano R., Aaron H.L., et al. Remote control of neuronal activity with a light-gated glutamate receptor. Neuron 54 (2007) 535-545
-
(2007)
Neuron
, vol.54
, pp. 535-545
-
-
Szobota, S.1
Gorostiza, P.2
Del Bene, F.3
Wyart, C.4
Fortin, D.L.5
Kolstad, K.D.6
Tulyathan, O.7
Volgraf, M.8
Numano, R.9
Aaron, H.L.10
-
10
-
-
29144480494
-
Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin
-
Li X., Gutierrez D.V., Hanson M.G., Han J., Mark M.D., Chiel H., Hegemann P., Landmesser L.T., and Herlitze S. Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin. PNAS 102 (2005) 17816-17821
-
(2005)
PNAS
, vol.102
, pp. 17816-17821
-
-
Li, X.1
Gutierrez, D.V.2
Hanson, M.G.3
Han, J.4
Mark, M.D.5
Chiel, H.6
Hegemann, P.7
Landmesser, L.T.8
Herlitze, S.9
-
11
-
-
23244433828
-
Optical imaging and control of genetically designated neurons in functioning circuits
-
Miesenbock G., and Kevrekidis I.G. Optical imaging and control of genetically designated neurons in functioning circuits. Annu Rev Neurosci 28 (2005) 533-563
-
(2005)
Annu Rev Neurosci
, vol.28
, pp. 533-563
-
-
Miesenbock, G.1
Kevrekidis, I.G.2
-
12
-
-
34147162254
-
High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice
-
This paper describes a transgenic strategy for using ChR2 to map neural circuitry in intact tissue.
-
Wang H., Peca J., Matsuzaki M., Matsuzaki K., Noguchi J., Qiu L., Wang D., Zhang F., Boyden E., Deisseroth K., et al. High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice. PNAS 104 (2007) 8143-8148. This paper describes a transgenic strategy for using ChR2 to map neural circuitry in intact tissue.
-
(2007)
PNAS
, vol.104
, pp. 8143-8148
-
-
Wang, H.1
Peca, J.2
Matsuzaki, M.3
Matsuzaki, K.4
Noguchi, J.5
Qiu, L.6
Wang, D.7
Zhang, F.8
Boyden, E.9
Deisseroth, K.10
-
13
-
-
27744514302
-
Rapid neurotransmitter uncaging in spatially defined patterns
-
This study demonstrates the use of caged glutamate to deliver spatially defined stimulation patterns to individual neurons.
-
Shoham S., O'Connor D.H., Sarkisov D.V., and Wang S.S.H. Rapid neurotransmitter uncaging in spatially defined patterns. Nat Methods 2 (2005) 837-843. This study demonstrates the use of caged glutamate to deliver spatially defined stimulation patterns to individual neurons.
-
(2005)
Nat Methods
, vol.2
, pp. 837-843
-
-
Shoham, S.1
O'Connor, D.H.2
Sarkisov, D.V.3
Wang, S.S.H.4
-
14
-
-
27144466742
-
Hippocampal CA1 circuitry dynamically gates direct cortical inputs preferentially at theta frequencies
-
Ang C.W., Carlson G.C., and Coulter D.A. Hippocampal CA1 circuitry dynamically gates direct cortical inputs preferentially at theta frequencies. J Neurosci 25 (2005) 9567-9580
-
(2005)
J Neurosci
, vol.25
, pp. 9567-9580
-
-
Ang, C.W.1
Carlson, G.C.2
Coulter, D.A.3
-
15
-
-
11344255402
-
Perisomatic feedback inhibition underlies cholinergically induced fast network oscillations in the rat hippocampus in vitro
-
Uses VSDI to measure circuit level activity flow to obtain mechanistic insight into gamma oscillation control in CA3 of hippocampus.
-
Mann E.O., Suckling J.M., Hajos N., Greenfield S.A., and Paulsen O. Perisomatic feedback inhibition underlies cholinergically induced fast network oscillations in the rat hippocampus in vitro. Neuron 45 (2005) 105. Uses VSDI to measure circuit level activity flow to obtain mechanistic insight into gamma oscillation control in CA3 of hippocampus.
-
(2005)
Neuron
, vol.45
, pp. 105
-
-
Mann, E.O.1
Suckling, J.M.2
Hajos, N.3
Greenfield, S.A.4
Paulsen, O.5
-
16
-
-
33644551834
-
Optical probing of neuronal circuit dynamics: genetically encoded versus classical fluorescent sensors
-
Knopfel T., Diez-Garcia J., and Akemann W. Optical probing of neuronal circuit dynamics: genetically encoded versus classical fluorescent sensors. Trends Neurosci 29 (2006) 160-166
-
(2006)
Trends Neurosci
, vol.29
, pp. 160-166
-
-
Knopfel, T.1
Diez-Garcia, J.2
Akemann, W.3
-
17
-
-
0034668168
-
Quantification of optical signals with electrophysiological signals in neural activities of Di-4-ANEPPS stained rat hippocampal slices
-
Tominaga T., Tominaga Y., Yamada H., Matsumoto G., and Ichikawa M. Quantification of optical signals with electrophysiological signals in neural activities of Di-4-ANEPPS stained rat hippocampal slices. J Neurosci Methods 102 (2000) 11
-
(2000)
J Neurosci Methods
, vol.102
, pp. 11
-
-
Tominaga, T.1
Tominaga, Y.2
Yamada, H.3
Matsumoto, G.4
Ichikawa, M.5
-
18
-
-
0037443068
-
Spatiotemporal dynamics of sensory responses in layer 2/3 of rat barrel cortex measured in vivo by voltage-sensitive dye imaging combined with whole-cell voltage recordings and neuron reconstructions
-
This paper demonstrates many key aspects of voltage activity imaging in an in vivo experimental system.
-
Petersen C.C.H., Grinvald A., and Sakmann B. Spatiotemporal dynamics of sensory responses in layer 2/3 of rat barrel cortex measured in vivo by voltage-sensitive dye imaging combined with whole-cell voltage recordings and neuron reconstructions. J Neurosci 23 (2003) 1298-1309. This paper demonstrates many key aspects of voltage activity imaging in an in vivo experimental system.
-
(2003)
J Neurosci
, vol.23
, pp. 1298-1309
-
-
Petersen, C.C.H.1
Grinvald, A.2
Sakmann, B.3
-
19
-
-
8344243726
-
VSDI: a new era in functional imaging of cortical dynamics
-
Grinvald A., and Hildesheim R. VSDI: a new era in functional imaging of cortical dynamics. Nat Rev Neurosci 5 (2004) 874
-
(2004)
Nat Rev Neurosci
, vol.5
, pp. 874
-
-
Grinvald, A.1
Hildesheim, R.2
-
20
-
-
34547125241
-
High-speed imaging reveals neurophysiological links to behavior in an animal model of depression
-
[Epub 2007 July 5]. This study demonstrates the use of fast activity imaging to isolate a neurophysiological endophenotype of depression-related behavior, and to quantify the functional role of neurogenesis in this disease model.
-
Airan R., Meltzer L.A., Roy M., Gong Y., Chen H., and Deisseroth K. High-speed imaging reveals neurophysiological links to behavior in an animal model of depression. Science 317 5839 (2007) 819-823 [Epub 2007 July 5]. This study demonstrates the use of fast activity imaging to isolate a neurophysiological endophenotype of depression-related behavior, and to quantify the functional role of neurogenesis in this disease model.
-
(2007)
Science
, vol.317
, Issue.5839
, pp. 819-823
-
-
Airan, R.1
Meltzer, L.A.2
Roy, M.3
Gong, Y.4
Chen, H.5
Deisseroth, K.6
-
21
-
-
0023128067
-
Simultaneous optical recording of activity from many neurons during feeding in Navanax
-
London J.A., Zecevic D., and Cohen L.B. Simultaneous optical recording of activity from many neurons during feeding in Navanax. J Neurosci 7 (1987) 649-661
-
(1987)
J Neurosci
, vol.7
, pp. 649-661
-
-
London, J.A.1
Zecevic, D.2
Cohen, L.B.3
-
22
-
-
0035503765
-
Functionally independent columns of rat somatosensory barrel cortex revealed with voltage-sensitive dye imaging
-
This paper uses VSDI with RH-155 to determine functional independence of barrel cortical columns.
-
Petersen C.C.H., and Sakmann B. Functionally independent columns of rat somatosensory barrel cortex revealed with voltage-sensitive dye imaging. J Neurosci 21 (2001) 8435-8446. This paper uses VSDI with RH-155 to determine functional independence of barrel cortical columns.
-
(2001)
J Neurosci
, vol.21
, pp. 8435-8446
-
-
Petersen, C.C.H.1
Sakmann, B.2
-
23
-
-
34147126914
-
In vivo light-induced activation of neural circuitry in transgenic mice expressing Channelrhodopsin-2
-
With [12], this paper demonstrates a transgenic strategy to utilizing ChR2 to map neural circuitry; in this case with in vivo applications.
-
Arenkiel B.R., Peca J., Davison I.G., Feliciano C., Deisseroth K., Augustine G.J., Ehlers M.D., and Feng G. In vivo light-induced activation of neural circuitry in transgenic mice expressing Channelrhodopsin-2. Neuron 54 (2007) 205-218. With [12], this paper demonstrates a transgenic strategy to utilizing ChR2 to map neural circuitry; in this case with in vivo applications.
-
(2007)
Neuron
, vol.54
, pp. 205-218
-
-
Arenkiel, B.R.1
Peca, J.2
Davison, I.G.3
Feliciano, C.4
Deisseroth, K.5
Augustine, G.J.6
Ehlers, M.D.7
Feng, G.8
-
24
-
-
23844500078
-
Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS
-
Willner P. Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS. Neuropsychobiology 52 (2005) 90-110
-
(2005)
Neuropsychobiology
, vol.52
, pp. 90-110
-
-
Willner, P.1
-
25
-
-
19944418868
-
Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test
-
Cryan J.F., Valentino R.J., and Lucki I. Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test. Neurosci Biobehav Rev 29 (2005) 547
-
(2005)
Neurosci Biobehav Rev
, vol.29
, pp. 547
-
-
Cryan, J.F.1
Valentino, R.J.2
Lucki, I.3
-
26
-
-
33645109592
-
Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment
-
Warner-Schmidt J.L., and Duman R.S. Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment. Hippocampus 16 (2006) 239-249
-
(2006)
Hippocampus
, vol.16
, pp. 239-249
-
-
Warner-Schmidt, J.L.1
Duman, R.S.2
-
27
-
-
0036328118
-
The validity of animal models of predisposition to depression
-
Willner P., and Mitchell P. The validity of animal models of predisposition to depression. Behav Pharmacol 13 (2002) 169-188
-
(2002)
Behav Pharmacol
, vol.13
, pp. 169-188
-
-
Willner, P.1
Mitchell, P.2
-
28
-
-
0345118159
-
Deep brain stimulation for Parkinson's disease
-
Benabid A.L. Deep brain stimulation for Parkinson's disease. Curr Opin Neurobiol 13 (2003) 696-706
-
(2003)
Curr Opin Neurobiol
, vol.13
, pp. 696-706
-
-
Benabid, A.L.1
-
29
-
-
33751237934
-
Cellular principles underlying normal and pathological activity in the subthalamic nucleus
-
Bevan M.D., Atherton J.F., and Baufreton J. Cellular principles underlying normal and pathological activity in the subthalamic nucleus. Curr Opin Neurobiol 16 (2006) 621-628
-
(2006)
Curr Opin Neurobiol
, vol.16
, pp. 621-628
-
-
Bevan, M.D.1
Atherton, J.F.2
Baufreton, J.3
-
30
-
-
33947187417
-
In vivo calcium imaging from genetically specified target cells in mouse cerebellum
-
Diez-Garcia J., Akemann W., and Knopfel T. In vivo calcium imaging from genetically specified target cells in mouse cerebellum. NeuroImage 34 (2007) 859-869
-
(2007)
NeuroImage
, vol.34
, pp. 859-869
-
-
Diez-Garcia, J.1
Akemann, W.2
Knopfel, T.3
-
31
-
-
0035959949
-
A miniature head-mounted two-photon microscope. high-resolution brain imaging in freely moving animals
-
This study extends cortical two-photon imaging from anesthetized to freely moving animals.
-
Helmchen F., Fee M.S., Tank D.W., and Denk W. A miniature head-mounted two-photon microscope. high-resolution brain imaging in freely moving animals. Neuron 31 6 (2001 Sep 27) 903-912. This study extends cortical two-photon imaging from anesthetized to freely moving animals.
-
(2001)
Neuron
, vol.31
, Issue.6
, pp. 903-912
-
-
Helmchen, F.1
Fee, M.S.2
Tank, D.W.3
Denk W4
-
32
-
-
30944448496
-
Fiber-optic fluorescence imaging
-
This paper covers the development and application of portable microendoscopy systems for in vivo imaging studies.
-
Flusberg B.A., Cocker E.D., Piyawattanametha W., Jung J.C., Cheung E.L.M., and Schnitzer M.J. Fiber-optic fluorescence imaging. Nat Methods 2 (2005) 941-950. This paper covers the development and application of portable microendoscopy systems for in vivo imaging studies.
-
(2005)
Nat Methods
, vol.2
, pp. 941-950
-
-
Flusberg, B.A.1
Cocker, E.D.2
Piyawattanametha, W.3
Jung, J.C.4
Cheung, E.L.M.5
Schnitzer, M.J.6
|