Instability of familial spongiform encephalopathy-related prion mutants

Biochemical and Biophysical Research Communications

Volumn 366, Issue 1, 2008, Pages 244-249

  Watanabe, Yasuko ^a   Hiraoka, Wakako ^b   Shimoyama, Yuhei ^c   Horiuchi, Motohiro ^a   Kuwabara, Mikinori ^a   Inanami, Osamu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b MEIJI UNIVERSITY   (Japan)

^c MURORAN INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Conformational stability; Conformational transition; D178N; ESR; Familial spongiform encephalopathy; Histidine residue; pH sensitivity; Prion protein; Salt bridge; SDSL

Indexed keywords

CYSTEINE; PRION PROTEIN; TYROSINE;

ARTICLE; BRAIN DISEASE; BRAIN SPONGIOSIS; ELECTRON SPIN RESONANCE; NUCLEAR MAGNETIC RESONANCE; PH; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STABILITY; X RAY CRYSTALLOGRAPHY;

MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN FOLDING; PRPC PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 37549025841     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.11.145     Document Type: Article

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