Isolation and characterization of a novel human RGS mutant displaying gain-of-function activity

Cellular Signalling

Volumn 20, Issue 2, 2008, Pages 323-336

  Hill, Claire ^a   Brownlie, Zoe ^b   Davey, John ^a   Milligan, Graeme ^b   Ladds, Graham ^c  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

G protein; Gain of function; GPCR; RGS

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HYBRID PROTEIN; RGS PROTEIN; RGS4 PROTEIN; SERINE;

ALPHA CHAIN; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; SCHIZOSACCHAROMYCES POMBE; SIGNAL TRANSDUCTION; YEAST;

AMINO ACID SEQUENCE; CELL LINE; CONSERVED SEQUENCE; DNA MUTATIONAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPINEPHRINE; GENES, REPORTER; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HUMANS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION; PHEROMONES; PROTEIN TRANSPORT; RGS PROTEINS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SERINE;

EID: 37549022656     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2007.10.016     Document Type: Article

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