The effects of physiological and pharmacological weight loss on adiponectin and leptin mRNA levels in the rat epididymal adipose tissue

European Journal of Pharmacology

Volumn 579, Issue 1-3, 2008, Pages 433-438

  Naderali, Ebrahim K ^a   Fatani, Sameer ^a   Telles, Monica ^b   Hunter, Leif ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Fenofibrate; Leptin mRNA; Obesity; Weight loss Adiponectin

Indexed keywords

ADIPONECTIN; FATTY ACID; FENOFIBRATE; INSULIN; LEPTIN; MESSENGER RNA; TRIACYLGLYCEROL;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; COMPARATIVE STUDY; CONTROLLED STUDY; DIET; EPIDIDYMIS FAT; FATTY ACID BLOOD LEVEL; GENE EXPRESSION; GLUCOSE INTAKE; INSULIN BLOOD LEVEL; MALE; METABOLISM; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT REDUCTION;

ADIPONECTIN; ADIPOSE TISSUE; ANIMALS; ANTILIPEMIC AGENTS; EPIDIDYMIS; FATTY ACIDS, NONESTERIFIED; GENE EXPRESSION REGULATION; LEPTIN; MALE; OBESITY; PROCETOFEN; RANDOM ALLOCATION; RATS; RATS, WISTAR; RNA, MESSENGER; TRIGLYCERIDES; WEIGHT LOSS;

EID: 37549021442     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.11.026     Document Type: Article

References (45)

1. Arita Y., Kihara S., Ouchi N., Takahashi M., Maeda K., Miyagawa J., Hotta K., Shimomura I., Nakamura T., Miyaoka K., Kuriyama H., Nishida M., Yamashita S., Okubo K., Matsubara K., Muraguchi M., Ohmoto Y., Funahashi T., and Matsuzawa Y. Paradoxial decrease of an adipose-specific protein, adiponectin, in obesity. Biochem. Biophys. Res. Commun. 257 (1999) 79-83
2. Arvidsson E., Viguerie N., Andersson I., Verdich C., Langin D., and Arner P. Effects of different hypocaloric diets on protein secretion from adipose tissue of obese women. Diabetes 53 (2004) 1966-1971
3. Ballantyne G.H., Gumbs A., and Modlin I.M. Changes in insulin resistance following bariatric surgery and the adipoinsular axis: role of the adipocytokines, leptin, adiponectin and resistin. Obes. Surg. 15 (2005) 692-699
4. Barnea M., Shamay A., Stark A.H., and Madar Z. A high-fat diet has a tissue-specific effect on adiponectin and related enzyme expression. Obesity 14 (2006) 2145-2153
5. Berg A.H., Combs T.P., Du X., Brownlee M., and Scherer P.E. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat. Med. 7 (2001) 947-953
6. Berg A.H., Combs T.P., and Scherer P.E. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol. Metab. 13 (2002) 84-89
7. Bouloumie A., Drexler H.C., Lafontan M., and Busse R. Leptin, the product of Ob gene, promotes angiogenesis. Circ. Res. 83 (1998) 1059-1066
8. Combs T.P., Wanger J.A., Berger J., Doebber T., Wang W.J., Zhang B.B., Tanen M., Berg A.H., O'Rahilly S., Savage D.B., Chatterjee K., Weiss S., Larson P.J., Gottesdiener K.M., Gertz B.J., Charron M.J., Scherer P.E., and Moller D.E. Induction of adipocyte complement-related protein of 30 kD by PPARγ agonist: a potential mechanism of insulin sensitisation. Endocrinology 143 (2002) 998-1007
9. Damci T., Tatliagac S., Osar Z., and Ilkova H. Fenofibrate treatment is associated with better glycemic control and lower serum leptin and insulin levels in type 2 diabetic patients with hypertriglyceridemia. Eur. J. Intern. Med. 14 (2003) 357-360
10. Flegal K.M., Carroll M.D., Ogden C.L., and Johnson C.L. Prevalence and trends in obesity among US adults, 1999-2000. JAMA 288 (2002) 1723-1727
11. Fruebis J., Tsao T.S., Javorschi S., Ebbets-Reed D., Erickson M.R., Yen F.T., Bihain B.E., and Lodish H.F. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muschle and causes weight loss in mice. Proc. Natl. Acad. Sci. 98 (2001) 2005-2010
12. Fruhbeck G. Pivotal role of nitric oxide in the control of blood pressure after leptin administration. Diabetes 48 (1999) 903-908
13. Gavrila A., Chan J.L., Yiannakouris N., Kontogianni M., Miller L.C., Orlova C., and Mantzoros C.S. Serum adiponectin levels are inversely associated with overall and central fat distribution but are not directly regulated by acute fasting or leptin administration in humans: cross-sectional and interventional studies. J. Clin. Endocrinol. Metab. 88 (2003) 4823-4831
14. Gustafson B., Jack M.M., Cushman S.W., and Smith U. Adiponectin gene activation by thiazolidinediones requires PPAR gamma 2, but not C/EBP alpha-evidence for differential regulation of the aP2 and adiponectin genes. Biochem. Biophys. Res. Commun. 308 (2003) 933-939
15. Hu E., Liang P., and Spiegelman B.M. AdipoQ is a novel adipocyte-spesific gene dysregulated in obesity. J. Biol. Chem. 271 (1996) 10679-10703
16. Hu X., She M., Hou H., Li Q., Shen Q., Luo Y., and Yin W. Adiponectin decreases plasma glucose and improves insulin sensitivity in diabetic swine. Acta. Biochim. Biophys. Sin. 39 (2007) 131-136
17. Kern P.A., Di Gregorio G.B., Lu T., Rassouli N., and Ranganathan G. Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression. Diabetes 52 (2003) 1779-1785
18. Koh K.K., Han S.H., Quon M.J., Yeal Ahn J., and Shin E.K. Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hypertriglyceridemia. Diabetes Care 28 (2005) 1419-1424
19. Kopp H.P., Krzyzanowska K., Mohlig M., Spranger J., Pfeiffer A.F., and Schernthaner G. Effects of marked weight loss on plasma levels of adiponectin, markers of chronic subclinical inflammation and insulin resistance in morbidly obese women. Int. J. Obes. Relat. Metab. Disord. 29 (2005) 766-771
20. Lembo G., Vecchione C., Fratta L., Marino G., Trimarco V., d'Amati G., and Trimarco B. Leptin induces direct vasodilation through distinct endothelial mechanisms. Diabetes 49 (2000) 293-297
21. Mallamaci F., Zoccali C., Cuzzola F., Tripepi G., Cutrupi S., Parlongo S., Tanaka S., Ouchi N., Kihara S., Funahashi T., and Matsuzawa Y. Adiponectin in essential hypertension. J. Nephrol. 15 (2002) 507-511
22. Miczke A., Szulinska M., Bogdanski P., and Pupek-Musialik D. Does a relationship exist between plasma adiponectin concentration and selected parameters of metabolic syndrome?. Pol. Merkur. Lek. 21 (2006) 170-172
23. Monzillo L.U., Hamdy O., Horton E.S., Ledbury S., Mullooly C., Jarema C., Porter S., Ovalle K., Moussa A., and Mantzoros C.S. Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance. Obes. Res. 11 (2003) 1048-1054
24. Mousavinasab F., Tahtinen T., Jokelainen J., Koskela P., Vanhala M., Oikarinen J., and Keinanen-Kiukaanniemi S. Lack of increase of serum adiponectin concentrations with a moderate weight loss during six months on a high-caloric diet in military service among a young male Finnish population. Endocrine 26 (2005) 65-70
25. Naderali E.K., Brwon M.J., Pickavance L.C., Wilding J.P.H., Doyle P.J., and Williams G. Dietary obesity in the rat induces endothelial dysfunction without causing insulin resistance: a possible role for triacylglycerols. Clin. Sci. 101 (2001) 499-506
26. Naderali E.K., Estadella D., Rocha M., Pickavance L.C., Fatani S., Denis R.G., and Williams G. A fat-enriched, glucose-enriched diet markedly attenuates adiponectin mRNA levels in rat epididymal adipose tissue. Clin Sci. 105 (2003) 403-408
27. Nakamura T., Tokunaga K., Shimomura I., Nishida M., Yoshida S., Kotani K., Islam A.H., Keno Y., Kobatake T., and Nagai Y. Contribution of visceral fat accumulation to the development of coronary artery disease in non-obese men. Atherosclerosis 107 (1994) 239-246
28. Nakano Y., Tobe T., Choi-Miura N.H., Mazda T., and Tomita M. Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J. Biochem. 120 (1996) 803-812
29. Okamoto Y., Arita Y., Nishida M., Muraguchi M., Ouchi N., Takahashi M., Igura T., Inui Y., Kihara S., Nakamura T., Yamashita S., Miyagawa J., Funahashi T., and Matsuzawa Y. An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls. Horm. Metab. Res. 32 (2000) 47-50
30. Ouchi N., Kihara S., Arita Y., Maeda K., Kuriyama H., Okamoto Y., Hotta K., Nishida M., Takahashi M., Nakamura T., Yamashita S., Funahashi T., and Matsuzawa Y. Novel modulator for endothelial adhesion molecules-adipocyte-derived plasma protein adiponectin. Circulation 100 (1999) 2473-2476
31. Ouchi N., Kihara S., Arita Y., Okamoto Y., Maeda K., Kuriyama H., Hotta K., Nishida M., Takahashi M., Muraguchi M., Ohmoto Y., Nakamura T., Yamashita S., Funahashi T., and Matsuzawa Y. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NK-kappa B signalling through a cAMP-dependent pathway. Circulation 102 (2000) 1296-1301
32. Ouchi N., Kihara S., Arita Y., Nishida M., Matsuyama A., Okamoto Y., Ishigami M., Kuriyama H., Kishida K., Nishizawa H., Hotta K., Muraguchi M., Ohmoto Y., Yamashita S., Funahashi T., and Matsuzawa Y. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human momocyte-derived macrophages. Circulation 103 (2001) 1057-1063
33. Paolisso G., Tagliamonte M.R., Galderisi M., Zito G.A., Petrocelli A., Carella C., de Divitiis O., and Varricchio M. Plasma leptin level is associated with myocardial wall thickness in hypertensive insulin-resistant men. Hypertension 34 (1999) 1047-1052
34. Ranheim T., Haugen F., Staff A.C., Braekke K., Harsem N.K., and Drevon C.A. Adiponectin is reduced in gestational diabetes mellitus in normal weight women. Acta. Obstet. Gynecol. Scand. 83 (2004) 341-347
35. Soderberg S., Ahren B., Jansson J.H., Johnson O., Hallmans G., Asplund K., and Olsson T. Leptin is associated with increased risk of myocardial infarction. J. Intern. Med. 246 (1999) 409-418
36. Statnick M.A., Beavers L.S., Conner L.J., Corominola H., Johnson D., Hammond C.D., Rafaeloff-Phail R., Seng T., Suter T.M., Sluka J.P., Ravussin E., Gadski R.A., and Caro J.F. Decreased expression of apM1 in omental and subcutaneous adipose tissue of human with type 2 diabetes. Int. J. Reprod. Diabetes Res. 1 (2000) 51-58
37. Trayhurn P., and Duncan J.S. Rapid chemiluminescent detection of the mRNA for uncoupling protein in brown adipose tissue by northern hybridization with a 32-mer oligonucleotide end-labelled with digoxigenin. Int. J. Obes. Relat. Metab. Disord. 18 (1994) 449-452
38. Trayhurn P., Duncan J.S., and Rayner D.V. Acute cold-induced suppression of ob (obese) gene-expression in white adipose-tissue of mice-mediation by the sympathetic system. Biochem. J. 311 (1995) 729-733
39. Velkoska E., Cole T.J., and Morris M.J. Early dietary intervention: long-term effects on blood pressure, brain neuropeptide Y, and adiposity markers. Am. J. Physiol. Endocrinol. Metab. 288 (2005) E1236-E1243
40. Viguerie N., Vidal H., Arner P., Holst C., Verdich C., Avizou S., Astrup A., Saris W.H., Macdonald I.A., Klimcakova E., Clement K., Martinez A., Hoffstedt J., Sorensen T.I., and Langin D. Nutrient-gene interactions in human obesity-implications for dietary guideline (NUGENOB) project. Adipose tissue gene expression in obese subjects during low-fat and high-fat hypocaloric diets. Diabetologia 48 (2005) 123-131
41. Wallace A.M., McMahon A.D., Packard C.J., Kelly A., Shepherd J., Gaw A., and Sattar N. Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS). Circulation 104 (2001) 3052-3056
42. Weyer C., Funahashi T., Tanaka S., Hotta K., Matsuzawa Y., Pratley R.E., and Tataranni P.A. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J. Clin. Endocrinol. Metab. 86 (2001) 1930-1935
43. Wolfe B.E., Jimerson D.C., Orlova C., and Mantzoros C.S. Effect of dieting on plasma leptin, soluble leptin receptor, adiponectin and resistin levels in healthy volunteers. Clin. Endocrinol. 61 (2004) 332-338
44. Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., Mori Y., Ide T., Murakami K., Tsuboyama-Kasaoka N., Ezaki O., Akanuma Y., Gavrilova O., Vinson C., Reitman M.L., Kagechika H., Shudo K., Yoda M., Nakano Y., Tobe K., Nagai R., Kimura S., Tomita M., Froguel P., and Kadowaki T. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7 (2001) 941-946
45. Yang B., Brown K.K., Chen L., Carrick K.M., Clifton L.G., McNulty J.A., Winegar D.A., Strum J.C., Stimpson S.A., and Pahel G.L. Serum adiponectin as a biomarker for in vivo PPARgamma activation and PPARgamma agonist-induced efficacy on insulin sensitization/lipid lowering in rats. BMC Pharmacol. 4 (2004) 23