Micro-Rayleigh-Bénard convection polymerase chain reaction system

Journal of Micro/Nanolithography, MEMS, and MOEMS

Volumn 6, Issue 4, 2007, Pages

  Yao, Da Jeng ^a   Chen, Jhao Ronga ^b   Ju, Woan Tying ^b  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NONE

Author keywords

Feedback; Flows; Microchannel plates; Microelectromechanical system; Temperature; Thermal effects

Indexed keywords

COMPUTATIONAL FLUID DYNAMICS; FEEDBACK CONTROL; MEMS; THERMAL EFFECTS;

MICROCHANNEL PLATES; MOLECULAR BIOLOGICAL METHOD; POLYMERASE CHAIN REACTION (PCR);

MOLECULAR BIOLOGY;

EID: 37549015603     PISSN: 19325150     EISSN: 19325134     Source Type: Journal    
DOI: 10.1117/1.2805452     Document Type: Article

References (21)

1. M. A. Northrup, M. T. Ching, R. M. White, and R. T. Watson, " DNA amplification with a microfabricated reaction chamber., " in Transducers '93, pp. 924-926 (1993).
2. M. A. Northrup, C. Gonzalez, D. Hadley, R. F. Hills, S. L. P. Landre, R. Saiki, J. J. Sninsky, and R. Watson, " A MEMS-based miniature DNA analysis system., " in Solid-State Sensors Actuators Eurosensors IX, pp. 764-767 (1995).
3. J. H. Daniel, S. Iqbal, R. B. Millington, D. E. Moorf, C. R. Lowe, D. I. Leslie, M. A. Lee, and M. J. Pearce, " Silicon microchamber for DNA amplification., " Sens. Actuators, A 71 (1-2), 81-88 (1998).
4. C. G. J. Schabmueller, M. A. Lee, A. G. R. Evans, A. Bruunnschweiler, G. J. Ensell, and D. L. Leslie, " Closed chamber PCR chips for DNA amplification., " Eng. Sci. Educ. J. 9 (6), 259-264 (2000).
5. Z. Zhan, C. Dafu, Y. Zhongyao, and W. Li, " Biochip of PCR amplification in silicon., " in 1st Annu. Int. IEEE-EMBS Spec. Top. Conf. Microtechnol. Med. Biol., pp. 25-28 (2000).
6. M. U. Kopp, A. J. de Mello, and A. Manz, " Chemical amplification-continuous PCR on a chip., " Science 280 (5366), 1046-1048 (1998).
7. C. F. Chou, R. Changrani, P. Roberts, D. Sadler, S. Lin, A. Mulholland, N. Swami, R. Terbrueggen, and F. Zenhaysern, " A miniaturized cyclic PCR device., " in Micro Total Analysis Systems 2001, pp. 151-152 (2001).
8. K. Sun, A. Yamaguchi, Y. Ishida, S. Matsuo, and H. Misawa, " A heater-integrated transparent microchannel chip for continuous-flow PCR., " Sens. Actuators B 84 (2-3), 283-289 (2002).
9. R. P. Oda, M. A. Strausbauch, A. F. R. Huhmer, N. Borson, S. R. Jurrens, J. Craighead, P. J. Wettstein, B. Eckloff, B. Kline, and J. P. Landers, " Infrared-mediated thermocycling for ultrafast polymerase chain reaction amplification of DNA., " Anal. Chem. 70 (20), 4361-4368 (1998).
10. M. N. Slyadnev, Y. Tanaka, M. Tokeshi, and T. Kitamori, " Photothermal temperature control of a chemical reaction on a microchip using an infrared diode laser., " Anal. Chem. 73 (16), 4037-4044 (2001).
11. N. Agrawal and V. M. Ugaz, " A buoyancy-driven compact thermocycler for rapid PCR., " J. Assoc. Lab. Autom. 11 (4), 217-221 (2006).
12. M. Hennig and D. Braun, " Convective polymerase chain reaction around micro immersion heater., " Appl. Phys. Lett. 87 (18), 183901 (2005).
13. E. K. Wheeler, W. Benett, P. Stratton, J. Richards, A. Cen, K. D. Ness, J. Ortega, L. G. Li, T. H. Wesgraber, K. Goodson, and F. Milanovich, " Convectively driven polymerase chain reaction thermal cycler., " Anal. Chem. 76 (14), 4011-4016 (2004).
14. D. Braun, N. L. Goddard, and A. Libchaber, " Exponential DNA replication by laminar convection., " Phys. Rev. Lett. 91 (15), 158103 (2003).
15. G. Muller, G. Neumann, and W. Weber, " Natural convection in vertical Bridgman configuration., " J. Cryst. Growth 70 (1-2), 78-93 (1984).
16. V. M. Ugaz and M. Krishnan, " Novel convective flow based approaches for high-throughput PCR thermocycling., " J. Assoc. Lab. Autom. 9 (5), 318-323 (2004).
17. E. Yariv, G. Ben-Dov, and K. D. Dorfman, " Polymerase chain reaction in natural convection systems: A convection-diffusion-reaction model., " Europhys. Lett. 71 (6), 1008-1014 (2005).
18. M. Krishnan, N. Agrawal, M. A. Burns, and V. M. Ugaz, " Reactions and fluidics in miniaturized natural convection systems., " Anal. Chem. 76 (21), 6254-6265 (2004).
19. Z. Chen, S. Qian, W. R. Abrams, D. Malamud, and H. H. Bau, " Thermosiphon-based PCR reactor: Experiment and modeling., " Anal. Chem. 76 (13), 3707-3715 (2004).
20. D. Braun, " PCR by thermal convection., " Mod. Phys. Lett. B 18 (16), 775-784 (2004).
21. V. M. Ugaz and M. Krishnan, " Novel convective flow based approaches for high-throughput PCR thermocycling., " J. Assoc. Lab. Autom. 9 (5), 318-323 (2004).