Comparison of immunohistochemical markers in the differential diagnosis of adrenocortical tumors: Immunohistochemical analysis of adrenocortical tumors

Applied Immunohistochemistry and Molecular Morphology

Volumn 16, Issue 1, 2008, Pages 32-39

  Zhang, Hongying ^a   Bu, Hong ^a   Chen, Huijiao ^a   Wei, Bing ^a   Liu, Weiping ^a   Guo, Jia ^a   Li, Fengyuan ^a   Liao, Dianying ^a   Tang, Yuan ^a   Zhang, Zhang ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Adrenocortical tumor; Calretinin; Differential diagnosis; Immunohistochemistry; Tissue microarray

Indexed keywords

BIOLOGICAL MARKER; CALRETININ; CD99 ANTIGEN; CYTOKERATIN; INHIBIN A; MELAN A; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY;

ADRENAL CORTEX CELL; ADRENAL CORTEX TUMOR; ADRENAL GLAND; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; DISEASE MARKER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MELANOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING; TISSUE MICROARRAY; TISSUE SECTION; TUMOR DIAGNOSIS;

ADRENAL CORTEX NEOPLASMS; ANTIGENS, NEOPLASM; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; DIAGNOSIS, DIFFERENTIAL; HUMANS; IMMUNOHISTOCHEMISTRY; INHIBINS; MICROARRAY ANALYSIS; NEOPLASM PROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 37549002436     PISSN: 15412016     EISSN: 15334058     Source Type: Journal    
DOI: 10.1097/PAI.0b013e318032cf56     Document Type: Article

References (34)

1. McCluggage WG, Burton J, Maxwell P, et al. Immunohistochemical staining of normal, hyperplastic, and neoplastic adrenal cortex with a monoclonal antibody against alpha inhibin. J Clin Pathol. 1998;51:114-116.
2. Loy TS, Phillips RW, Linder CL. A103 immunostaining in the diagnosis of adrenal cortical tumors: an immunohistochemical study of 316 cases. Arch Pathol Lab Pathol Med. 2002;126:170-172.
3. Ghorab Z, Jorda M, Ganjei P, et al. Melan A (A103) is expressed in adrenocortical neoplasms but not in renal cell and hepatocellular carcinomas. Appl Immunohistochem Mol Morphol. 2003;11:330-333.
4. Karim RZ, Wills EJ, McCarthy SW, et al. Myxoid variant of adrenocortical carcinoma: report of a unique case. Pathol Int. 2006;56:89-94.
5. Alsabeth R, Mazoujian G, Goates J, et al. Adrenal cortical tumors clinically mimicking pheochromocytoma. Am J Clin Pathol. 1995;104:382-390.
6. Komminoth P, Roth J, Schroder S, et al. Overlapping expression of immunohistochemical markers and synaptophysin mRNA in pheochromocytomas and adrenocortical carcinomas: implications for the differential diagnosis of adrenal gland tumors. Lab Invest. 1995;72:424-431.
7. Busam KJ, Iversen K, Coplan KA, et al. Immunoreactivity for A103, an antibody to Melan-A(Mart-1), in adrenocortical and other tumors. Am J Surg Pathol. 1998;22:57-63.
8. Shin SJ, Hoda RS, Ying L, et al. Diagnostic utility of the monoclonal antibody A103 in fine-needle aspiration biopsies of the adrenal. Am J Clin Pathol. 2000;113:295-302.
9. Renshaw AA, Granter SR. A comparison of A103 and inhibin reactivity in adrenal cortical tumors: distinction from hepatocellular carcinoma and renal tumors. Mod Pathol. 1998;11:1160-1164.
10. Arola J, Liu J, Keikkila P, et al. Expression of inhibin α in the human adrenal gland and adrenocortical tumors. Endo Res. 1998;24:865-867.
11. Cho EY, Ahn GH. Immunoexpression of inhibin α-subunit in adrenal neoplasms. Appl Immunohistochem Mol Morphol. 2001;9:222-228.
12. Pelkey TJ, Frierson HF Jr, Mills SE, et al. The alpha subunit of inhibin in adrenal cortical neoplasia. Mod Pathol. 1998;11:516-524.
13. Munro LMA, Kennedy A, McNicol AM. The expression of inhibin/activin subunits in the human adrenal cortex and its tumors. J Endo. 1999;161:341-347.
14. Zhang HY, Wang XJ, Liu WP, et al. Diagnostic value of A103 and inhibin-alpha in adrenocortical tumors: an immunohistochemical study using tissue microarray techniques. Zhonghua Bing Li Xue Za Zhi. 2004;33:203-207.
15. Granville LA, Younes M, Churg A, et al. Comparison of monoclonal versus polyclonal calretinin antibodies for immnunohistochemical diagnosis of malignant mesothelioma. Appl Immunohistochem Mol Morphol. 2005;13:75-79.
16. Andressen C, Blumcke I, Xelio MR. Calcium binding proteins: selective marker of nerve cells. Cell Tissue Res. 1993;271:181-208.
17. Doglioni C, Chiodera PL, Furlanetto A, et al. Calretinin: a specific mesothelial marker for evaluation of serous effusions [Abstract]. Mod Pathol. 1997;10:33.
18. Doglioni C, Dei Tos AP, Laurino L, et al. Calretinin: a novel immunocytochemical marker for mesothelioma. Am J Surg Pathol. 1996;20:1037-1046.
19. Barberis MCP, Faleri M, Veronese S, et al. Calretinin: a selective marker of normal and neoplastic mesothelial cells in serous effusions. Acta Cytol. 1997;41:1757-1761.
20. Jorda M, De MB, Nadji M. Calretinin and inhibin are useful in separating adrenocortical neoplasms from pheochromocytomas. Appl Immunohistochem Mol Morphol. 2002;10:67-70.
21. Zhang PJ, Genega EM, Tomaszewski JE, et al. The role of calretinin, inhibin, melan-A, bclL-2, and c-kit in differentiating adrenal cortical and medullary tumors: an immunohistochemical study. Mod Pathol. 2003;16:591-597.
22. Pann CC, Chen PC, Chiang H, et al. An easy method for manual construction of high-density tissue arrays. Appl Immunohistochem Mol Morphol. 2004;12:370-372.
23. Kim JY, Lim SJ, Park K. Cyclooxygenase and c-erbB-2 expression in colorectal carcinoma assessed using tissue microarrays. Appl Immunohistochem Mol Morphol. 2004;12:67-70.
24. Gaffey MJ, Traweek ST, Mills SE, et al. Cytokeratin expression in adrenocortical neoplasia: an immunohistochemical and biochemical study with implications for the differential diagnosis of adrenocortical, hepatocellular, and renal cell carcinoma. Hum Pathol. 1992;23:144-153.
25. Henzen-Logmans SC, Stel HV, van Muijen GN, et al. Expression of intermediate filament proteins in adrenal cortex and related tumours. Histopathology. 1988;12: 359-372.
26. Jungbluth AA, Iverson K, Coplan K, et al. Expression of melanocyte-associated markers gp-100 and Melan-A/MART-1 in angiomyolipomas. An immunohistochemical and rt-PCR analysis. Virchows Arch. 1999;434:429-435.
27. Schraith DF, Hahm GK, Niemann TH, et al. a-inhibin immunoreactivity in soft-tissue neoplasia. Mod Pathol. 2003;16:1205-1209.
28. Deavers MT, Malpica A, Liu J, et al. Ovarian sex cord-stromal tumors: an immunohistochemical study including a comparison of calretinin and inhibin. Mod Pathol. 2003;16:584-590.
29. Lugli A, Forster Y, Haas P, et al. Calretinin expression in human normal and neoplastic tissues: a tissue microarray analysis on 5233 tissue samples. Hum Pathol. 2003;34:994-1000.
30. Schraml P, Kononen J, Bubendorf L, et al. Tissue microarrays for gene amplification surveys in many different tumor types. Clin Cancer Res. 1999;5:1966-1975.
31. Camp RL, Charette LA, Rimm DL. Validation of tissue microarray technology in breast carcinoma. Lab Invest. 2000;80:1943-1949.
32. Fan Z, Rijin MAD, Montgomery K, et al. Hep Par 1 antibody stain for the differential diagnosis of hepatocellular carcinoma: 676 tumors tested using tissue microarrays and conventional tissue sections. Mod Pathol. 2003;16:137-144.
33. Hoos A, Urist MJ, Stojadinovic A, et al. Validation of tissue microarrays for immunohistochemical profiling of cancer specimens using the example of human fibroblastic tumors. Am J Pathol. 2001;158:1245-1251.
34. Ordonez NG. The immunohistochemical diagnosis of epithelial mesothelioma. Hum Pathol. 1999;30:313-323.