메뉴 건너뛰기




Volumn 115, Issue 11, 2007, Pages 1194-1205

Expression of CD44s and CD44v6 in transitional cell carcinomas of the urinary bladder: Comparison with tumour grade, proliferative activity and p53 immunoreactivity of tumour cells

Author keywords

CD44; Grade of tumour; Ki 67; p53; Urothelial cancer

Indexed keywords

HERMES ANTIGEN; PROTEIN P53;

EID: 37349114461     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0643.2007.00602.x     Document Type: Article
Times cited : (25)

References (47)
  • 2
    • 12344313091 scopus 로고    scopus 로고
    • Molecular pathways in bladder cancer
    • Williams SG, Stein JP. Molecular pathways in bladder cancer. Urol Res 2004 32 : 373 85.
    • (2004) Urol Res , vol.32 , pp. 373-85
    • Williams, S.G.1    Stein, J.P.2
  • 4
    • 0033853022 scopus 로고    scopus 로고
    • Contemporary management of superficial bladder cancer
    • Pow-Sang JM, Seigne JD. Contemporary management of superficial bladder cancer. Cancer Control 2000 7 : 335 9.
    • (2000) Cancer Control , vol.7 , pp. 335-9
    • Pow-Sang, J.M.1    Seigne, J.D.2
  • 5
    • 0035254218 scopus 로고    scopus 로고
    • Radical cystectomy in the treatment of invasive bladder cancer: Long-term results in 1,054 patients
    • Stein JP, Lieskovsky G, Cote R, Groshen S, Feng AC, Boyd S, et al. Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol 2001 19 : 666 75.
    • (2001) J Clin Oncol , vol.19 , pp. 666-75
    • Stein, J.P.1    Lieskovsky, G.2    Cote, R.3    Groshen, S.4    Feng, A.C.5    Boyd, S.6
  • 7
    • 0028133090 scopus 로고
    • Normal human tissues, in addition to some tumours, express multiple different CD44 isoforms
    • Fox SB, Fawcett J, Jackson DG, Collins I, Gatter KC, Harris AL, et al. Normal human tissues, in addition to some tumours, express multiple different CD44 isoforms. Cancer Res 1994 54 : 4539 46.
    • (1994) Cancer Res , vol.54 , pp. 4539-46
    • Fox, S.B.1    Fawcett, J.2    Jackson, D.G.3    Collins, I.4    Gatter, K.C.5    Harris, A.L.6
  • 9
    • 0031936838 scopus 로고    scopus 로고
    • Current status of CD44 variant isoforms as cancer diagnostic markers
    • Goodison S, Tarin D. Current status of CD44 variant isoforms as cancer diagnostic markers. Histopathology 1998 32 : 1 6.
    • (1998) Histopathology , vol.32 , pp. 1-6
    • Goodison, S.1    Tarin, D.2
  • 10
    • 0031874645 scopus 로고    scopus 로고
    • The normal structure and function of CD44 and its role in neoplasia
    • Sneath RJ, Mangham DC. The normal structure and function of CD44 and its role in neoplasia. Mol Pathol 1998 51 : 191 200.
    • (1998) Mol Pathol , vol.51 , pp. 191-200
    • Sneath, R.J.1    Mangham, D.C.2
  • 11
    • 0031910782 scopus 로고    scopus 로고
    • Forms and functions of CD44
    • Borland G, Ross JA, Guy K. Forms and functions of CD44. Immunology 1998 93 : 139 48.
    • (1998) Immunology , vol.93 , pp. 139-48
    • Borland, G.1    Ross, J.A.2    Guy, K.3
  • 12
    • 0019939967 scopus 로고
    • The gene, MIC4, which controls expression of the antigen defined by monoclonal antibody F10.44.2, is on human chromosome 11
    • Goodfellow PN, Banting G, Wiles MV, Tunnacliffe A, Parkar M, Solomon E, et al. The gene, MIC4, which controls expression of the antigen defined by monoclonal antibody F10.44.2, is on human chromosome 11. Eur J Immunol 1982 12 : 659 63.
    • (1982) Eur J Immunol , vol.12 , pp. 659-63
    • Goodfellow, P.N.1    Banting, G.2    Wiles, M.V.3    Tunnacliffe, A.4    Parkar, M.5    Solomon, E.6
  • 13
    • 0029111781 scopus 로고
    • Patterns of splice variant CD44 expression by normal human urothelium in situ and in vitro and by bladder-carcinoma cell lines
    • Southgate J, Trejdosiewicz LK, Smith B, Selby PJ. Patterns of splice variant CD44 expression by normal human urothelium in situ and in vitro and by bladder-carcinoma cell lines. Int J Cancer 1995 62 : 449 56.
    • (1995) Int J Cancer , vol.62 , pp. 449-56
    • Southgate, J.1    Trejdosiewicz, L.K.2    Smith, B.3    Selby, P.J.4
  • 14
    • 0028921474 scopus 로고
    • Correlation of expression of CD44 isoforms and E-cadherin with differentiation in human urothelial cell lines and transitional cell carcinoma
    • Hong RL, Pu YS, Chu JS, Lee WJ, Chen YC, Wu CW. Correlation of expression of CD44 isoforms and E-cadherin with differentiation in human urothelial cell lines and transitional cell carcinoma. Cancer Lett 1995 89 : 81 7.
    • (1995) Cancer Lett , vol.89 , pp. 81-7
    • Hong, R.L.1    Pu, Y.S.2    Chu, J.S.3    Lee, W.J.4    Chen, Y.C.5    Wu, C.W.6
  • 15
    • 0030965983 scopus 로고    scopus 로고
    • Expression of CD44v2 in transitional cell carcinoma of the urinary bladder and in urine
    • Müller M, Heicappell R, Habermann F, Kaufmann M, Steiner U, Miller K. Expression of CD44v2 in transitional cell carcinoma of the urinary bladder and in urine. Urol Res 1997 25 : 187 92.
    • (1997) Urol Res , vol.25 , pp. 187-92
    • Müller, M.1    Heicappell, R.2    Habermann, F.3    Kaufmann, M.4    Steiner, U.5    Miller, K.6
  • 16
    • 3242743136 scopus 로고    scopus 로고
    • In vitro culturing and characteristics of transit amplifying epithelial cells from human prostate tissue
    • Uzgare AR, Xu Y, Isaacs JT. In vitro culturing and characteristics of transit amplifying epithelial cells from human prostate tissue. J Cell Biochem 2004 91 : 196 205.
    • (2004) J Cell Biochem , vol.91 , pp. 196-205
    • Uzgare, A.R.1    Xu, Y.2    Isaacs, J.T.3
  • 17
    • 0033744728 scopus 로고    scopus 로고
    • Plasticity of the urothelial phenotype: Effects of gastro-intestinal mesenchyme/stroma and implications for urinary tract reconstruction
    • Li Y, Liu W, Hayward SW, Cunha GR, Baskin LS. Plasticity of the urothelial phenotype: effects of gastro-intestinal mesenchyme/stroma and implications for urinary tract reconstruction. Differentiation 2000 66 : 126 35.
    • (2000) Differentiation , vol.66 , pp. 126-35
    • Li, Y.1    Liu, W.2    Hayward, S.W.3    Cunha, G.R.4    Baskin, L.S.5
  • 18
    • 0031670939 scopus 로고    scopus 로고
    • Expression of CD44 standard and variant-v6 proteins in transitional cell bladder tumours and their relation to prognosis during a long-term follow-up
    • Lipponen P, Aaltoma S, Kosma VM, Ala-Opas M, Eskelinen M. Expression of CD44 standard and variant-v6 proteins in transitional cell bladder tumours and their relation to prognosis during a long-term follow-up. J Pathol 1998 186 : 157 64.
    • (1998) J Pathol , vol.186 , pp. 157-64
    • Lipponen, P.1    Aaltoma, S.2    Kosma, V.M.3    Ala-Opas, M.4    Eskelinen, M.5
  • 19
    • 0029007058 scopus 로고
    • Expressions of E-cadherin and exon v-6 containing isoforms of CD44 and their prognostic values in human transitional cell carcinoma
    • Hong RL, Pu YS, Hsieh TS, Chu JS, Lee WJ. Expressions of E-cadherin and exon v-6 containing isoforms of CD44 and their prognostic values in human transitional cell carcinoma. J Urol 1995 153 : 2025 8.
    • (1995) J Urol , vol.153 , pp. 2025-8
    • Hong, R.L.1    Pu, Y.S.2    Hsieh, T.S.3    Chu, J.S.4    Lee, W.J.5
  • 22
    • 0036870173 scopus 로고    scopus 로고
    • Expression of cathepsin D in urothelial carcinoma of the urinary bladder: An immunohistochemical study including correlations with extracellular matrix components, CD44, p53, Rb, c-erbB-2 and the proliferation indices
    • Ioachim E, Charchanti A, Stavropoulos N, Athanassiou E, Bafa M, Agnantis NJ. Expression of cathepsin D in urothelial carcinoma of the urinary bladder: an immunohistochemical study including correlations with extracellular matrix components, CD44, p53, Rb, c-erbB-2 and the proliferation indices. Anticancer Res 2002 22 : 3383 8.
    • (2002) Anticancer Res , vol.22 , pp. 3383-8
    • Ioachim, E.1    Charchanti, A.2    Stavropoulos, N.3    Athanassiou, E.4    Bafa, M.5    Agnantis, N.J.6
  • 23
    • 0032733225 scopus 로고    scopus 로고
    • Focal loss of CD44 variant protein expression is related to recurrence in superficial bladder carcinoma
    • Toma V, Hauri D, Schmid U, Ackermann D, Maurer R, Alund G, et al. Focal loss of CD44 variant protein expression is related to recurrence in superficial bladder carcinoma. Am J Pathol 1999 155 : 1427 32.
    • (1999) Am J Pathol , vol.155 , pp. 1427-32
    • Toma, V.1    Hauri, D.2    Schmid, U.3    Ackermann, D.4    Maurer, R.5    Alund, G.6
  • 25
    • 0030826329 scopus 로고    scopus 로고
    • The prognostic value of p53 nuclear overexpression and MIB-1 as proliferative marker in transitional cell carcinoma of the bladder
    • Popov Z, Hoznek A, Colombel M, Bastuji-Garin S, Lefrere-Belda MA, Bellot J, et al. The prognostic value of p53 nuclear overexpression and MIB-1 as proliferative marker in transitional cell carcinoma of the bladder. Cancer 1997 80 : 1472 81.
    • (1997) Cancer , vol.80 , pp. 1472-81
    • Popov, Z.1    Hoznek, A.2    Colombel, M.3    Bastuji-Garin, S.4    Lefrere-Belda, M.A.5    Bellot, J.6
  • 26
    • 0037103038 scopus 로고    scopus 로고
    • Proliferative activity is the most significant predictor of recurrence in noninvasive papillary urothelial neoplasms of low malignant potential and grade1 papillary carcinomas of the bladder
    • Pich A, Chiusa L, Formiconi A, Galliano D, Bortolin P, Comino A, et al. Proliferative activity is the most significant predictor of recurrence in noninvasive papillary urothelial neoplasms of low malignant potential and grade1 papillary carcinomas of the bladder. Cancer 2002 95 : 784 90.
    • (2002) Cancer , vol.95 , pp. 784-90
    • Pich, A.1    Chiusa, L.2    Formiconi, A.3    Galliano, D.4    Bortolin, P.5    Comino, A.6
  • 27
    • 0027161872 scopus 로고
    • Urothelial tissue culture for bladder reconstruction: An experimental study
    • Hutton KAR, Trejdosiewicz LK, Thomas DFM, Southgate J. Urothelial tissue culture for bladder reconstruction: an experimental study. J Urol 1993 150 : 721 5.
    • (1993) J Urol , vol.150 , pp. 721-5
    • Hutton, K.A.R.1    Trejdosiewicz, L.K.2    Thomas, D.F.M.3    Southgate, J.4
  • 28
    • 0028152842 scopus 로고
    • Normal human urothelial cells in vitro: Proliferation and induction of stratification
    • Southgate J, Hutton KAR, Thomas DFM, Trejdosiewicz LK. Normal human urothelial cells in vitro: proliferation and induction of stratification. Lab Invest 1994 71 : 583 93.
    • (1994) Lab Invest , vol.71 , pp. 583-93
    • Southgate, J.1    Hutton, K.A.R.2    Thomas, D.F.M.3    Trejdosiewicz, L.K.4
  • 29
    • 0027437531 scopus 로고
    • Proliferative state of the urothelium with benign and atypical changes. Correlation with transferrin and epidermal factor receptors and blood group antigens
    • Limas C. Proliferative state of the urothelium with benign and atypical changes. Correlation with transferrin and epidermal factor receptors and blood group antigens. J Pathol 1993 171 : 39 47.
    • (1993) J Pathol , vol.171 , pp. 39-47
    • Limas, C.1
  • 30
    • 0025306467 scopus 로고
    • Cell lineages and differentiation programs in epidermal, urothelial and hepatic tissues and their neoplasms
    • Marceau N. Cell lineages and differentiation programs in epidermal, urothelial and hepatic tissues and their neoplasms. Lab Invest 1990 63 : 4 20.
    • (1990) Lab Invest , vol.63 , pp. 4-20
    • Marceau, N.1
  • 31
    • 18844448732 scopus 로고    scopus 로고
    • Autocrine regulation of human urothelial cell proliferation and migration during regenerative responses in vitro
    • Varley C, Hill G, Pellegrin S, Shaw NJ, Selby PJ, Trejdosiewicz LK, et al. Autocrine regulation of human urothelial cell proliferation and migration during regenerative responses in vitro. Exp Cell Res 2005 306 : 216 29.
    • (2005) Exp Cell Res , vol.306 , pp. 216-29
    • Varley, C.1    Hill, G.2    Pellegrin, S.3    Shaw, N.J.4    Selby, P.J.5    Trejdosiewicz, L.K.6
  • 32
    • 0027759847 scopus 로고
    • P53 nuclear protein accumulation correlates with mutations in the p53 gene, tumour grade, and stage in bladder cancer
    • Esrig D, Spruck CH 3rd., Nichols PW, Chaiwun B, Steven K, Groshen S, et al. p53 nuclear protein accumulation correlates with mutations in the p53 gene, tumour grade, and stage in bladder cancer. Am J Pathol 1993 143 : 1389 97.
    • (1993) Am J Pathol , vol.143 , pp. 1389-97
    • Esrig, D.1    Spruck III, C.H.2    Nichols, P.W.3    Chaiwun, B.4    Steven, K.5    Groshen, S.6
  • 34
    • 0029063351 scopus 로고
    • Prognostic value of p53 overexpression in patients with invasive bladder cancer treated with neoadjuvant MVAC
    • Sarkis AS, Bajorin DF, Reuter VE, Herr HW, Netto G, Zhang ZF, et al. Prognostic value of p53 overexpression in patients with invasive bladder cancer treated with neoadjuvant MVAC. J Clin Oncol 1995 13 : 1384 90.
    • (1995) J Clin Oncol , vol.13 , pp. 1384-90
    • Sarkis, A.S.1    Bajorin, D.F.2    Reuter, V.E.3    Herr, H.W.4    Netto, G.5    Zhang, Z.F.6
  • 35
    • 0029102116 scopus 로고
    • Unusual retention of introns in CD44 gene transcripts in bladder cancer provides new diagnostic and clinical oncological opportunities
    • Matsumura Y, Sugiyama M, Matsumura S, Hayle AJ, Robinson P, Smith JC, et al. Unusual retention of introns in CD44 gene transcripts in bladder cancer provides new diagnostic and clinical oncological opportunities. J Pathol 1995 177 : 11 20.
    • (1995) J Pathol , vol.177 , pp. 11-20
    • Matsumura, Y.1    Sugiyama, M.2    Matsumura, S.3    Hayle, A.J.4    Robinson, P.5    Smith, J.C.6
  • 37
    • 14944371853 scopus 로고    scopus 로고
    • Expression of CD44v6 correlates with cell proliferation and cellular atypia in urothelial carcinoma cell lines 5637 and HT1197
    • Kuncová J, Kostrouch Z, Viale M, Revoltella R, Mandys V. Expression of CD44v6 correlates with cell proliferation and cellular atypia in urothelial carcinoma cell lines 5637 and HT1197. Folia Biol 2005 51 : 3 11.
    • (2005) Folia Biol , vol.51 , pp. 3-11
    • Kuncová, J.1    Kostrouch, Z.2    Viale, M.3    Revoltella, R.4    Mandys, V.5
  • 38
    • 0034024811 scopus 로고    scopus 로고
    • Expression of CD44 variants and prognosis in oesophageal squamous cell carcinoma
    • Gotoda T, Matsumura Y, Kondo H, Ono H, Kanamoto A, Kato H, et al. Expression of CD44 variants and prognosis in oesophageal squamous cell carcinoma. Gut 2000 46 : 14 19.
    • (2000) Gut , vol.46 , pp. 14-19
    • Gotoda, T.1    Matsumura, Y.2    Kondo, H.3    Ono, H.4    Kanamoto, A.5    Kato, H.6
  • 39
    • 0033634883 scopus 로고    scopus 로고
    • CD44 and its v6 spliced variant in lung carcinomas: Relations to NCAM, CEA, EMA and UP1 and prognostic significance
    • Nguyen VN, Mirejovský T, Melínová L, Mandys V. CD44 and its v6 spliced variant in lung carcinomas: relations to NCAM, CEA, EMA and UP1 and prognostic significance. Neoplasma 2000 47 : 400 8.
    • (2000) Neoplasma , vol.47 , pp. 400-8
    • Nguyen, V.N.1    Mirejovský, T.2    Melínová, L.3    Mandys, V.4
  • 40
    • 0033965121 scopus 로고    scopus 로고
    • CD44. a marker of squamous differentiation in adenosquamous neoplasms
    • Ylagan LR, Scholes J, Demopoulos R. CD44. A marker of squamous differentiation in adenosquamous neoplasms. Arch Pathol Lab Med 2000 124 : 212 5.
    • (2000) Arch Pathol Lab Med , vol.124 , pp. 212-5
    • Ylagan, L.R.1    Scholes, J.2    Demopoulos, R.3
  • 41
    • 0025810796 scopus 로고
    • Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67
    • Gerdes J, Li L, Schlueter C, Duchrow M, Wohlenberg C, Gerlach C, et al. Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. Am J Pathol 1991 138 : 867 73.
    • (1991) Am J Pathol , vol.138 , pp. 867-73
    • Gerdes, J.1    Li, L.2    Schlueter, C.3    Duchrow, M.4    Wohlenberg, C.5    Gerlach, C.6
  • 42
    • 0021212003 scopus 로고
    • Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67
    • Gerdes J, Lemke H, Baisch H, Wacker HH, Schwab U, Stein H. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 1984 133 : 1710 5.
    • (1984) J Immunol , vol.133 , pp. 1710-5
    • Gerdes, J.1    Lemke, H.2    Baisch, H.3    Wacker, H.H.4    Schwab, U.5    Stein, H.6
  • 43
    • 0034213106 scopus 로고    scopus 로고
    • MIB-1 as a proliferative marker in transitional cell carcinoma of the bladder: Clinical significance and comparison with other prognostic factors
    • Oosterhuis JW, Schapers RF, Janssen-Heijnen ML, Smeets AW, Pauwels RP. MIB-1 as a proliferative marker in transitional cell carcinoma of the bladder: clinical significance and comparison with other prognostic factors. Cancer 2000 88 : 2598 605.
    • (2000) Cancer , vol.88 , pp. 2598-605
    • Oosterhuis, J.W.1    Schapers, R.F.2    Janssen-Heijnen, M.L.3    Smeets, A.W.4    Pauwels, R.P.5
  • 44
    • 0027057589 scopus 로고
    • Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections
    • Cattoretti G, Becker MGH, Key G, Duchrow M, Schlueter C, Galle J, et al. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J Pathol 1991 168 : 357 63.
    • (1991) J Pathol , vol.168 , pp. 357-63
    • Cattoretti, G.1    Becker, M.G.H.2    Key, G.3    Duchrow, M.4    Schlueter, C.5    Galle, J.6
  • 45
    • 0025908985 scopus 로고
    • Progression and survival in transitional cell bladder cancer: A comparison of established prognostic factors, S phase fraction and DNA ploidy
    • Lipponen PK, Eskelinen MJ, Nordline S. Progression and survival in transitional cell bladder cancer: a comparison of established prognostic factors, S phase fraction and DNA ploidy. Eur J Cancer 1991 27 : 877 81.
    • (1991) Eur J Cancer , vol.27 , pp. 877-81
    • Lipponen, P.K.1    Eskelinen, M.J.2    Nordline, S.3
  • 46
  • 47
    • 0031717333 scopus 로고    scopus 로고
    • Molecular alterations in bladder cancer
    • Ørntoft TF, Wolf H. Molecular alterations in bladder cancer. Urol Res 1998 26 : 223 33.
    • (1998) Urol Res , vol.26 , pp. 223-33
    • Ørntoft, T.F.1    Wolf, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.