Effects of anthocyanins in black currant on retinal blood flow circulation of patients with normal tension glaucoma. A pilot study

Hirosaki Medical Journal

Volumn 59, Issue 1, 2007, Pages 23-32

  Ohguro, Ikuyo ^a   Ohguro, Hiroshi ^a   Nakazawa, Mitsuru ^b  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

Author keywords

Anthocyanins; Endothelin 1; Neuroprotection; Normal tension glaucoma; Ocular blood flow

Indexed keywords

EID: 37349107812     PISSN: 04391721     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Shields MB. An overview of glaucoma. In: Textbook of glaucoma. 4th ed. Baltimoa, Maryland: Williams & Wilkins; 1988.p.1-2.
2. The Advanced Glaucoma Intervention Study (AIGIS), The relationship between control of intraocular pressure and visual field deterioration. The AGIS Investigators. Am J Ophthalmol 2000;130:429-40.
3. Gordon MO, Beiser JA, Brandt JD, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, Parrish RK 2nd, Wilson MR, Kass MA. The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol 2002;120:714-20.
4. Anderson DR, Drance SM, Schulzer M, Collaborative Normal-Tension Glaucoma Study Group. Natural history of normal-tension glaucoma. Ophthalmology 2001;108:247-53.
5. Iwase A, Suzuki Y, Araie M, Yamamoto T, Abe H, Shirato S, Kuwayama Y, Mishima HK, Shimizu H, Tomita G, Inoue Y, Kitazawa Y, The Tajimi Study Group, Japan Glaucoma Society. The prevalence of primary open-angle glaucoma in Japanese. The Tajim Study. Ophthalmology 2004;111:1641-8.
6. Gloster J. Incidence of optic disc haemorrhages in chronic simple glaucoma and ocular hypertension. Br J Ophthalmol 1981;65:452-6.
7. Yamamoto T, Maeda M, Sawada A, Sugiyama K, Taniguchi T, Kitazawa Y, Oyama Z, Ichihashi N, Takagi H, Kitajima Y. Prevalence of normal-tension glaucoma and primary open-angle glaucoma in patients with collagen diseases. Jpn J Ophthalmol 1999;43:539-42.
8. Ohguro I, Yamamoto Y, Takeuchi K, Ohguro H, Matsumoto M, Matsuhashi H, Nakazawa M. Relation between platelet aggregation rate and pathogenesis of glaucomatous optic neuropathy. Journal of the Eye 2005;22:669-72.
9. Ohguro I, Ohguro H, Ohkuro H, Nakazawa M. Study of contribution of low level of plasma endothelin-1 concentration to pathogenesis of glaucomatous optic neuropathy. Hirosaki Med J 2006;57:59-64.
10. Renaud S, de Logeril M. Wine, alcohol, platelets, and the French paradox for coromary heart disease. LANCET 1992;339:1523-6.
11. Scialdone D. L'Azione delle antocianine sul senso luminoso. Ann Oftalmol Clin Ocul 1988;92:43-51.
12. Nakaishi H, Matsumoto H, Tominaga S, Hirayama M. Effects of blackcurrant anthocyanoides intake on dark adaptation and VDT work-induced transient refractive alternation in healthy humans. Altern Med Rev 2000;5:553-62.
13. Matsumoto H, Kamm KE, Stull JT, Azuma H. Delphinidine-3-rutiniside relaxes the bovine ciliary smooth muscle through activation of ETB receptor and NO/cGMP pathway. Exp Eye Res 2005;80:313-22.
14. Levin LA, Louhab A. Apoptosis of retinal ganglion cells in anterior ischemic optic neuropathy. Arch Ophthalmol 1996;114:488-91.
15. Henry E, Newby DE, Webb DJ, O'Brien C. Peripheral endothelial dysfunction in normal pressure glaucoma. Invest Ophthalmol Vis Sci 1999;96:1710-4.
16. Findl O, Strenn K, Wolzt M, Menapace R, Vass C, Eichler HG, Schmetterer L. Effects of changes in intraocular pressure on human ocular haemodynamics. Curr Eye Res 1997;16:1024-9.
17. Ohguro I, Ishikawa F, Ouguro H, Shimokawa R, Nakazawa M. Arterial sclerosis grade in normal-tension glaucoma patients. Journal of the Eye 2004;21:397-400.
18. Breddin HK, Lippold R, Bittner M, Kirchmaier CM, Krzywanek HJ, Michaelis J. Spontaneous platelet aggregation as a predictive risk factor for vascular occlusions in healthy volunteers? Results of the HAPARG study. Haemostatic parameters as risk factors in healthy volunteers. Atherosclerosis 1999;144:211-9.
19. Bojic L, Skare LL. Circulating platelet aggregates in glaucoma. Int Ophthalmol 1998-1999;22:151-4.
20. Gasser P. Ocular vasospasm: a risk factor in the pathogenesis of low-tension glaucoma. Int Ophthalmol 1989;13:281-90.
21. Maruyama I, Ohguro H, Ikeda Y. Retinal ganglion cells recognized by serum autoantibody against γ-enolase found in glaucoma patients. Invest Ophthalmol Vis Sci 2000;41:1657-65.
22. Wax MB, Tezel G, Saito I, Gupta RS, Harley JB, Li Z, Romano C. Anti-Ro/SS-A positivity and heat shock protein antibodies in patients with normal-pressure glaucoma. Am J Ophthalmol 1998;125:145-57.
23. Dreyer EB, Zurakowski D, Schumer RA, Podos SM, Lipton SA. Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma. Arch Ophthalmol 1996;114:299-305.
24. Neufeld AH, Hernandes R, Gonzalez M. Nitric oxide syntheses in the human glaucomatous optic nerve head. Arch Ophthalmol 1997;115:497-503.
25. Haefliger IO, Dettman ES, Liu R, Meyer P, Prunte C, Messerli J, Flammer J. Potential role of nitric oxide and endothelin in the pathogenesis of glaucoma. Surv Ophthalmol 1999;43 (Suppl 1): S51-8.
26. Logan JF, Rankin SJ, Jackson AJ. Retinal blood flow measurements and neuroretinal rim damage in glaucoma. Br J Ophthalmol 2004;88:1049-54.
27. Yaoeda K, Shirakashi M, Fukushima A, Funaki S, Funaki H, Abe H, Tanabe N. Relationship between optic nerve head microcirculation and visual field loss in glaucoma. Acta Ophthalmol Scand 2003;81:253-9.
28. Sato EA, Ohtake Y, Shinoda K, Mashima Y, Kimura I. Decreased blood flow at neuroretinal rim of optic nerve head correponds with visual field deficit in eyes with normal tension glaucoma. Graefes Arch Clin Exp Ophthalmol 2006;244:795-801.
29. Hafez AS, Bizzarro RLG, Lesk MR. Evaluation of optic nerve head and peripapillary retinal blood flow in glaucoma patients, ocular hypertensives, and normal subjects. Am J Ophthalmol 2003;136:1022-31.
30. 2+-antagonist on visual field in low-tension glaucoma. Graefe's Arch Clin Exp Ophthalmol 1989;227:408-12.
31. Netland PA, Chaturvedi N, Dryer EB. Calcium channel blockers in the managenent of low-tension and open-angle glaucoma. Am J Ophthalmol 1993;115:608-13.
32. Sawada A, Kitazawa Y, Yamamoto T, Okabe I, Ichien K. Prevention of visual field defect progression with brovincamine in eyes with normal-tension glaucoma. Ophthalmology 1996;103: 283-8.
33. Tomita K, Araie M, Tamaki Y, Nagahara M, Sugiyama T. Effects of nilvadipine, a calcium antagonist, on rabbit ocular circulation and optic nerve head circulation in NTG subjects. Invest Ophthalmol Vis Sci 1999;40:1144-51.
34. Embleton SJ, Hosking SL, Roff-Hilton EJ, Cunliffe IA. Effect of senescence on ocular blood flow in the retina, neuroretinal rim and lamina cribrosa, using scanning laser Doppler flowmetry. Eye 2002;16:156-62.
35. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988;332:411-5.
36. MacCumber MW, D' Anna SA. Endothelin receptor-binding subtypes in the human retina and choroid. Arch Ophthalmol 1994;112:1231-5.
37. Ripodas A, de Juan JA, Roldan-Pallares M, Bernal R, Moya J, Chao M, Lopez A, Fernandez-Cruz A, Fernandez-Durango R. Localisation of endothelin-1 mRNA expression and immunoreactivity in the retina and optic nerve from human and porcine eye. Evidence for endothelin-1 expression in astrocytes. Brain Res 2001;912:13743.
38. Oku H, Kida T, Sugiyama T, Hamada J, Sato B, Ikeda T. Possible involvement of endothelin-1 and nitric oxide in the pathogenesis of proliferative diabetic retinopathy. Retina 2001;21:647-51.
39. Sugiyama T, Moriya S, Oku H, Azuma I. Association of endothelin-1 with normal tension glaucoma. Clinical and fundamental studies. Surv Ophthalmol 1995;39 (Suppl 1):S49-56.
40. Cellini M, Possati GL, Profazio V, Sbrocca M, Caramazza N, Caramazza R. Color Doppler imaging and plasma levels of endothelin-1 in low-tension glaucoma. Acta Ophthalmol Scand 1997;224 (Suppl):S11-3.
41. Kaiser HJ, Flammer J, Wenk M, Luschur T. Endothelin-1 plasma levels in normal-tension glaucoma. Abnormal response to postural changes. Graefe's Arch Clin Exp Ophthalmol 1995;233:484-8.
42. Nicolela MT, Ferrier SN, Morrison CA, Archibald ML, Levatte TL, Wallace K, Chauhau BC, LeBlanc RP. Effects of cold-induced vasospasm in glaucoma:the role of endothelin-1. Invest Ophthalmol Vis Sci 2003;44:2565-72.