Heritability of autistic traits in the general population

Archives of Pediatrics and Adolescent Medicine

Volumn 161, Issue 4, 2007, Pages 372-377

  Hoekstra, Rosa A ^a   Bartels, Meike ^a   Verweij, Catharina J H ^a   Boomsma, Dorret I ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; AUTISM; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; FEMALE; HERITABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCORING SYSTEM; SEX DIFFERENCE; STRUCTURAL EQUATION MODELING; TWINS;

ADOLESCENT; AUTISTIC DISORDER; DISEASES IN TWINS; FEMALE; HUMANS; MALE; SEX FACTORS;

EID: 34147174531     PISSN: 10724710     EISSN: 15383628     Source Type: Journal    
DOI: 10.1001/archpedi.161.4.372     Document Type: Article

References (37)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Washington, DC: American Psychiatric Association; 2000.
2. Rutter M. Genetic studies of autism: from the 1970s into the millennium. J Abnorm Child Psychol. 2000;28:3-14.
3. Folstein S, Rutter M. Genetic influences and infantile autism. Nature. 1977;265:726-728.
4. Bailey A, Le Couteur A, Gottesman I, et al. Autism as a strongly genetic disorder: evidence from a British twin study. Psychol Med. 1995;25:63-77.
5. Le Couteur A, Bailey A, Goode S, et al. A broader phenotype of autism: the clinical spectrum in twins. J Child Psychol Psychiatry. 1996;37:785-801.
6. Bolton P, Macdonald H, Pickles A, et al. A case-control family history study of autism. J Child Psychol Psychiatry. 1994;35:877-900.
7. Piven J, Palmer P, Jacobi D, Childress D, Arndt S. Broader autism phenotype: evidence from a family history study of multiple-incidence autism families. Am J Psychiatry. 1997;154:185-190.
8. Bailey A, Palferman S, Heavey L, Le Couteur A. Autism: the phenotype in relatives. J Autism Dev Disord. 1998;28:369-392.
9. Constantino JN, Todd RD. Autistic traits in the general population: a twin study. Arch Gen Psychiatry. 2003;60:524-530.
10. Baron-Cohen S, Wheelwright S, Skinner R, Martin CE. The Autism-Spectrum quotient (AQ): evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. J Autism Dev Disord. 2001;31:5-17.
11. Spiker D, Lotspeich LJ, Dimiceli S, Myers RM, Risch N. Behavioral phenotypic variation in autism multiplex families: evidence for a continuous severity gradient. Am J Med Genet. 2002;114:129-136.
12. Constantino JN, Lajonchere C, Lutz M, et al. Autistic social impairment in the siblings of children with pervasive developmental disorders. Am J Psychiatry. 2006;163:294-296.
13. Bishop DVM, Maybery M, Maley A, Wong D, Hill W, Hallmayer J. Using self-report to identify the broad phenotype in parents of children with autistic spectrum disorders: a study using the Autism-Spectrum Quotient. J Child Psychol Psychiatry. 2004;45:1431-1436.
14. Constantino JN, Todd RD. Intergenerational transmission of subthreshold autistic traits in the general population. Biol Psychiatry. 2005;57:655-660.
15. Constantino JN, Todd RD. Genetic structure of reciprocal social behavior. Am J Psychiatry. 2000;157:2043-2045.
16. Ronald A, Happe F, Plomin R. The genetic relationship between individual differences in social and nonsocial behaviours characteristic of autism. Dev Sci. 2005;8:444-458.
17. Ronald A, Happe F, Bolton P, et al. Genetic heterogeneity between the three components of the autism spectrum: a twin study. J Am Acad Child Adolesc Psychiatry. 2006;45:691-699.
18. Achenbach TM, McConaughy SH, Howell CT. Child/adolescent behavioral and emotional problems: implications of cross-informant correlations for situational specificity. Psychol Bull. 1987;101:213-232.
19. Verhulst FC, van der Ende J. Agreement between parents' reports and adolescents' self-reports of problem behavior. J Child Psychol Psychiatry. 1992;33:1011-1023.
20. Baron-Cohen S. The hyper-systemizing, assortative mating theory of autism. Prog Neuropsychopharmacol Biol Psychiatry. 2006;30:865-872.
21. Phillips K, Fulker DW, Carey G, Nagoshi CT. Direct marital assortment for cognitive and personality variables. Behav Genet. 1988;18:347-356.
22. Mascie-Taylor CG, Vandenberg SG. Assortative mating for IQ and personality due to propinquity and personal preference. Behav Genet. 1988;18:339-345.
23. Watson D, Klohnen EC, Casillas A, Simms EN, Haig J, Berry DS. Match makers and deal breakers: analyses of assortative mating in newlywed couples. J Pers. 2004;72:1029-1068.
24. Boomsma DI, Orlebeke JF, Van Baal GCM. The Dutch Twin Register: growth data on weight and height. Behav Genet. 1992;22:247-251.
25. Boomsma DI, Vink JM, Van Beijsterveldt CEM, et al. Netherlands Twin Register: a focus on longitudinal research. Twin Res. 2002;5:401-406.
26. Rietveld MJH, Der Valk JC, Bongers IL, Stroet TM, Slagboom PE, Boomsma DI. Zygosity diagnosis in young twins by parental report. Twin Res. 2000;3:134-141.
27. Neale MC, Boker SM, Xie G, Maes HH. Mx: Statistical Modeling, Revised. 6th ed. Richmond: Virginia Commonwealth University; 2005.
28. Wakabayashi A, Baron-Cohen S, Wheelwright S, Tojo Y. The Autism-Spectrum Quotient (AQ) in Japan: a cross-cultural comparison. J Autism Dev Disord. 2006;36:263-270.
29. Fombonne E. Epidemiological surveys of autism and other pervasive developmental disorders: an update. J Autism Dev Disord. 2003;33:365-382.
30. Greenberg DA, Hodge SE, Sowinski J, Nicoll D. Excess of twins among affected sibling pairs with autism: implications for the etiology of autism. Am J Hum Genet. 2001;69:1062-1067.
31. Betancur C, Leboyer M, Gillberg C. Increased rate of twins among affected sibling pairs with autism. Am J Hum Genet. 2002;70:1381-1383.
32. Hallmayer J, Glasson EJ, Bower C, et al. On the twin risk in autism. Am J Hum Genet. 2002;71:941-946.
33. Croen LA, Grether JK, Selvin S. Descriptive epidemiology of autism in a California population: who is at risk? J Autism Dev Disord. 2002;32:217-224.
34. Hultman CM, Sparen P, Cnattingius S. Perinatal risk factors for infantile autism. Epidemiology. 2002;13:417-423.
35. Szatmari P, Jones MB, Zwaigenbaum L, MacLean JE. Genetics of autism: overview and new directions. J Autism Dev Disord. 1998;28:351-368.
36. Posthuma D, Boomsma DI. A note on the statistical power in extended twin designs. Behav Genet. 2000;30:147-158.
37. Posserud MB, Lundervold AJ, Gillberg C. Autistic features in a total population of 7-9-year-old children assessed by the ASSQ (Autism Spectrum Screening Questionnaire). J Child Psychol Psychiatry. 2006;47:167-175.