Contribution of prostaglandin D2 via prostanoid DP receptor to nasal hyperresponsiveness in guinea pigs repeatedly exposed to antigen

European Journal of Pharmacology

Volumn 578, Issue 2-3, 2008, Pages 286-291

  Yasui, Kiyoshi ^a   Asanuma, Fujio ^a   Hirano, Yosuke ^a   Shichijo, Michitaka ^a   Deguchi, Masashi ^a   Arimura, Akinori ^a  

^a SHIONOGI AND CO LTD   (Japan)

Author keywords

Allergic rhinitis; Histamine; Nasal blockage; Nasal hyperresponsiveness; PGD2; Prostanoid DP receptor; S 5751; TXA2; U46619

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 7 [(1 ,2 ,3 ,5) 2 (5 HYDROXYBENZO[B]THIOPHEN 3 YLCARBONYLAMINO) 10 NORPINAN 3 YL]HEPT 5 ENOIC ACID; ALLERGEN; HISTAMINE; PROSTAGLANDIN D2; PROSTANOID; PROSTANOID DP RECEPTOR; PROSTANOID RECEPTOR; UNCLASSIFIED DRUG; 7(2 (5 HYDROXYBENZO(B)THIOPHEN 3 YLCARBONYLAMINO) 10 NORPINAN 3 YL)HEPT 5 ENOIC ACID; 7(2-(5-HYDROXYBENZO(B)THIOPHEN-3-YLCARBONYLAMINO)-10-NORPINAN-3-YL)HEPT-5-ENOIC ACID; IMMUNOGLOBULIN RECEPTOR; OVALBUMIN; PROSTAGLANDIN D2 RECEPTOR; PROSTAGLANDIN RECEPTOR; THIOPHENE DERIVATIVE;

ALLERGIC RHINITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; DRUG EXPOSURE; DRUG INHIBITION; DRUG SYNTHESIS; GUINEA PIG; INFLAMMATORY CELL; INTRANASAL PRESSURE; MALE; MAST CELL; NONHUMAN; NOSE CONGESTION; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; SENSITIZATION; ANIMAL; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; INTRANASAL DRUG ADMINISTRATION; METABOLISM; NOSE; NOSE OBSTRUCTION; PATHOPHYSIOLOGY; PERENNIAL RHINITIS; PRESSURE; TIME;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ADMINISTRATION, INTRANASAL; ALLERGENS; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; GUINEA PIGS; HISTAMINE; MALE; NASAL OBSTRUCTION; NOSE; OVALBUMIN; PRESSURE; PROSTAGLANDIN D2; RECEPTORS, IMMUNOLOGIC; RECEPTORS, PROSTAGLANDIN; RHINITIS, ALLERGIC, PERENNIAL; THIOPHENES; TIME FACTORS;

EID: 37349094328     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.09.014     Document Type: Article

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