Hepatocellular toxicity of kava leaf and root extracts

Phytomedicine

Volumn 15, Issue 1-2, 2008, Pages 120-131

  Lüde, Saskia ^a   Török, Michael ^a   Dieterle, Sandy ^a   Jäggi, René ^b   Büter, Karin Berger ^b   Krähenbühl, Stephan ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b Vitaplant Ltd   (Switzerland)

Author keywords

Apoptosis; Hepatocellular toxicity; HepG2 cells; Kava kava extract; Necrosis; Piper methysticum

Indexed keywords

ADENOSINE TRIPHOSPHATE; DEMETHOXYYANGONIN; DIHYDROKAWAIN; DIHYDROMETHYSTICIN; GLUTATHIONE; KAVA; KAWAIN; LACTATE DEHYDROGENASE; METHYSTICIN; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; YANGONIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE POTENTIAL; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; FATTY ACID OXIDATION; FLUORESCENCE ACTIVATED CELL SORTING; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIVER MITOCHONDRION; LIVER TOXICITY; MASS SPECTROMETRY; MITOCHONDRIAL TOXICITY; NONHUMAN; PLANT LEAF; PLANT ROOT; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN;

ACETONE; ACUTE TOXICITY TESTS; ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; HEPATOCYTES; HUMANS; KAVA; METHANOL; MITOCHONDRIA, LIVER; NECROSIS; OXIDATION-REDUCTION; PLANT EXTRACTS; PLANT LEAVES; PLANT ROOTS; RATS;

PIPER METHYSTICUM; RATTUS;

EID: 37349091412     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2007.11.003     Document Type: Article

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