-
1
-
-
0142062150
-
Chapter 1: human papillomavirus and cervical cancer-burden and assessment of causality
-
Bosch F.X., and de Sanjose S. Chapter 1: human papillomavirus and cervical cancer-burden and assessment of causality. J Natl Cancer Inst Monogr (2003) 3-13
-
(2003)
J Natl Cancer Inst Monogr
, pp. 3-13
-
-
Bosch, F.X.1
de Sanjose, S.2
-
2
-
-
0036559896
-
Papillomaviruses and cancer: from basic studies to clinical application
-
zur Hausen H. Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer 2 (2002) 342-350
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 342-350
-
-
zur Hausen, H.1
-
3
-
-
6344253201
-
Mechanisms of human papillomavirus-induced oncogenesis
-
Munger K., Baldwin A., Edwards K.M., Hayakawa H., Nguyen C.L., Owens M., et al. Mechanisms of human papillomavirus-induced oncogenesis. J Virol 78 (2004) 11451-11460
-
(2004)
J Virol
, vol.78
, pp. 11451-11460
-
-
Munger, K.1
Baldwin, A.2
Edwards, K.M.3
Hayakawa, H.4
Nguyen, C.L.5
Owens, M.6
-
4
-
-
31144456195
-
HPV-mediated cervical carcinogenesis: concepts and clinical implications
-
Snijders P.J., Steenbergen R.D., Heideman D.A., and Meijer C.J. HPV-mediated cervical carcinogenesis: concepts and clinical implications. J Pathol 208 (2006) 152-164
-
(2006)
J Pathol
, vol.208
, pp. 152-164
-
-
Snijders, P.J.1
Steenbergen, R.D.2
Heideman, D.A.3
Meijer, C.J.4
-
5
-
-
33845905779
-
The natural history of cervical HPV infection: unresolved issues
-
Woodman C.B., Collins S.I., and Young L.S. The natural history of cervical HPV infection: unresolved issues. Nat Rev Cancer 7 (2007) 11-22
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 11-22
-
-
Woodman, C.B.1
Collins, S.I.2
Young, L.S.3
-
6
-
-
30144443269
-
Paradoxical roles of the immune system during cancer development
-
de Visser K.E., Eichten A., and Coussens L.M. Paradoxical roles of the immune system during cancer development. Nat Rev Cancer 6 (2006) 24-37
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 24-37
-
-
de Visser, K.E.1
Eichten, A.2
Coussens, L.M.3
-
7
-
-
0036995759
-
Epithelial carcinogenesis: dynamic interplay between neoplastic cells and their microenvironment
-
van Kempen L.C., Rhee J.S., Dehne K., Lee J., Edwards D.R., and Coussens L.M. Epithelial carcinogenesis: dynamic interplay between neoplastic cells and their microenvironment. Differentiation 70 (2002) 610-623
-
(2002)
Differentiation
, vol.70
, pp. 610-623
-
-
van Kempen, L.C.1
Rhee, J.S.2
Dehne, K.3
Lee, J.4
Edwards, D.R.5
Coussens, L.M.6
-
8
-
-
0036454102
-
CD34(+) fibrocytes in normal cervical stroma, cervical intraepithelial neoplasia III, and invasive squamous cell carcinoma of the cervix uteri
-
Barth P.J., Ramaswamy A., and Moll R. CD34(+) fibrocytes in normal cervical stroma, cervical intraepithelial neoplasia III, and invasive squamous cell carcinoma of the cervix uteri. Virchows Arch 441 (2002) 564-568
-
(2002)
Virchows Arch
, vol.441
, pp. 564-568
-
-
Barth, P.J.1
Ramaswamy, A.2
Moll, R.3
-
9
-
-
31044433663
-
Macrophages: obligate partners for tumor cell migration, invasion, and metastasis
-
Condeelis J., and Pollard J.W. Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell 124 (2006) 263-266
-
(2006)
Cell
, vol.124
, pp. 263-266
-
-
Condeelis, J.1
Pollard, J.W.2
-
10
-
-
31544441610
-
Distinct role of macrophages in different tumor microenvironments
-
Lewis C.E., and Pollard J.W. Distinct role of macrophages in different tumor microenvironments. Cancer Res 66 (2006) 605-612
-
(2006)
Cancer Res
, vol.66
, pp. 605-612
-
-
Lewis, C.E.1
Pollard, J.W.2
-
11
-
-
7644231561
-
The chemokine system in diverse forms of macrophage activation and polarization
-
Mantovani A., Sica A., Sozzani S., Allavena P., Vecchi A., and Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25 (2004) 677-686
-
(2004)
Trends Immunol
, vol.25
, pp. 677-686
-
-
Mantovani, A.1
Sica, A.2
Sozzani, S.3
Allavena, P.4
Vecchi, A.5
Locati, M.6
-
12
-
-
33750813483
-
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression
-
Martinez F.O., Gordon S., Locati M., and Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol 177 (2006) 7303-7311
-
(2006)
J Immunol
, vol.177
, pp. 7303-7311
-
-
Martinez, F.O.1
Gordon, S.2
Locati, M.3
Mantovani, A.4
-
13
-
-
2642547301
-
Inflammatory cells contribute to the generation of an angiogenic phenotype in pancreatic ductal adenocarcinoma
-
Esposito I., Menicagli M., Funel N., Bergmann F., Boggi U., Mosca F., et al. Inflammatory cells contribute to the generation of an angiogenic phenotype in pancreatic ductal adenocarcinoma. J Clin Pathol 57 (2004) 630-636
-
(2004)
J Clin Pathol
, vol.57
, pp. 630-636
-
-
Esposito, I.1
Menicagli, M.2
Funel, N.3
Bergmann, F.4
Boggi, U.5
Mosca, F.6
-
14
-
-
0002598345
-
Mast cell infiltration around gastric cancer cells correlates with tumor angiogenesis and metastasis
-
Yano H., Kinuta M., Tateishi H., Nakano Y., Matsui S., Monden T., et al. Mast cell infiltration around gastric cancer cells correlates with tumor angiogenesis and metastasis. Gastric Cancer 2 (1999) 26-32
-
(1999)
Gastric Cancer
, vol.2
, pp. 26-32
-
-
Yano, H.1
Kinuta, M.2
Tateishi, H.3
Nakano, Y.4
Matsui, S.5
Monden, T.6
-
15
-
-
33644674149
-
The absence of CCL2 expression in cervical carcinoma is associated with increased survival and loss of heterozygosity at 17q11.2
-
Zijlmans H.J., Fleuren G.J., Baelde H.J., Eilers P.H., Kenter G.G., and Gorter A. The absence of CCL2 expression in cervical carcinoma is associated with increased survival and loss of heterozygosity at 17q11.2. J Pathol 208 (2006) 507-517
-
(2006)
J Pathol
, vol.208
, pp. 507-517
-
-
Zijlmans, H.J.1
Fleuren, G.J.2
Baelde, H.J.3
Eilers, P.H.4
Kenter, G.G.5
Gorter, A.6
-
16
-
-
0037372178
-
Inducible nitric oxide synthase expression in human colorectal cancer: correlation with tumor angiogenesis
-
Cianchi F., Cortesini C., Fantappie O., Messerini L., Schiavone N., Vannacci A., et al. Inducible nitric oxide synthase expression in human colorectal cancer: correlation with tumor angiogenesis. Am J Pathol 162 (2003) 793-801
-
(2003)
Am J Pathol
, vol.162
, pp. 793-801
-
-
Cianchi, F.1
Cortesini, C.2
Fantappie, O.3
Messerini, L.4
Schiavone, N.5
Vannacci, A.6
-
17
-
-
0036679421
-
Relationship between the expression of iNOS, VEGF, tumor angiogenesis and gastric cancer
-
Song Z.J., Gong P., and Wu Y.E. Relationship between the expression of iNOS, VEGF, tumor angiogenesis and gastric cancer. World J Gastroenterol 8 (2002) 591-595
-
(2002)
World J Gastroenterol
, vol.8
, pp. 591-595
-
-
Song, Z.J.1
Gong, P.2
Wu, Y.E.3
-
18
-
-
33846781716
-
Alpha- and betapapillomavirus E6/E7 genes differentially modulate pro-inflammatory gene expression
-
De Andrea M., Mondini M., Azzimonti B., Dell'oste V., Germano S., Gaudino G., et al. Alpha- and betapapillomavirus E6/E7 genes differentially modulate pro-inflammatory gene expression. Virus Res 124 (2007) 220-225
-
(2007)
Virus Res
, vol.124
, pp. 220-225
-
-
De Andrea, M.1
Mondini, M.2
Azzimonti, B.3
Dell'oste, V.4
Germano, S.5
Gaudino, G.6
-
19
-
-
5644288566
-
Nested PCR with the PGMY09/11 and GP5(+)/6(+) primer sets improves detection of HPV DNA in cervical samples
-
Fuessel Haws A.L., He Q., Rady P.L., Zhang L., Grady J., Hughes T.K., et al. Nested PCR with the PGMY09/11 and GP5(+)/6(+) primer sets improves detection of HPV DNA in cervical samples. J Virol Methods 122 (2004) 87-93
-
(2004)
J Virol Methods
, vol.122
, pp. 87-93
-
-
Fuessel Haws, A.L.1
He, Q.2
Rady, P.L.3
Zhang, L.4
Grady, J.5
Hughes, T.K.6
-
20
-
-
33244466951
-
Immunohistochemical expression of p16(INK4a) is predictive of HR-HPV infection in cervical low-grade lesions
-
Benevolo M., Mottolese M., Marandino F., Vocaturo G., Sindico R., Piperno G., et al. Immunohistochemical expression of p16(INK4a) is predictive of HR-HPV infection in cervical low-grade lesions. Mod Pathol 19 (2006) 384-391
-
(2006)
Mod Pathol
, vol.19
, pp. 384-391
-
-
Benevolo, M.1
Mottolese, M.2
Marandino, F.3
Vocaturo, G.4
Sindico, R.5
Piperno, G.6
-
21
-
-
18744377513
-
p16INK4A and p14ARF expression pattern by immunohistochemistry in human papillomavirus-related cervical neoplasia
-
Wang J.L., Zheng B.Y., Li X.D., Nokelainen K., Angstrom T., Lindstrom M.S., et al. p16INK4A and p14ARF expression pattern by immunohistochemistry in human papillomavirus-related cervical neoplasia. Mod Pathol 18 (2005) 629-637
-
(2005)
Mod Pathol
, vol.18
, pp. 629-637
-
-
Wang, J.L.1
Zheng, B.Y.2
Li, X.D.3
Nokelainen, K.4
Angstrom, T.5
Lindstrom, M.S.6
-
22
-
-
0031646709
-
Comparison of microvessel density with tumor associated macrophages in invasive breast carcinoma
-
Jonjic N., Valkovic T., Lucin K., Iternicka Z., Krstulja M., Mustac E., et al. Comparison of microvessel density with tumor associated macrophages in invasive breast carcinoma. Anticancer Res 18 (1998) 3767-3770
-
(1998)
Anticancer Res
, vol.18
, pp. 3767-3770
-
-
Jonjic, N.1
Valkovic, T.2
Lucin, K.3
Iternicka, Z.4
Krstulja, M.5
Mustac, E.6
-
23
-
-
0029816609
-
Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
-
Leek R.D., Lewis C.E., Whitehouse R., Greenall M., Clarke J., and Harris A.L. Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res 56 (1996) 4625-4629
-
(1996)
Cancer Res
, vol.56
, pp. 4625-4629
-
-
Leek, R.D.1
Lewis, C.E.2
Whitehouse, R.3
Greenall, M.4
Clarke, J.5
Harris, A.L.6
-
24
-
-
0034266661
-
Tumor associated macrophages in human prostate cancer: relation to clinicopathological variables and survival
-
Lissbrant I.F., Stattin P., Wikstrom P., Damber J.E., Egevad L., and Bergh A. Tumor associated macrophages in human prostate cancer: relation to clinicopathological variables and survival. Int J Oncol 17 (2000) 445-451
-
(2000)
Int J Oncol
, vol.17
, pp. 445-451
-
-
Lissbrant, I.F.1
Stattin, P.2
Wikstrom, P.3
Damber, J.E.4
Egevad, L.5
Bergh, A.6
-
25
-
-
0032926784
-
Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas
-
Nishie A., Ono M., Shono T., Fukushi J., Otsubo M., Onoue H., et al. Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas. Clin Cancer Res 5 (1999) 1107-1113
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1107-1113
-
-
Nishie, A.1
Ono, M.2
Shono, T.3
Fukushi, J.4
Otsubo, M.5
Onoue, H.6
-
26
-
-
0032867830
-
Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: association with angiogenesis and poor prognosis
-
Takanami I., Takeuchi K., and Kodaira S. Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: association with angiogenesis and poor prognosis. Oncology 57 (1999) 138-142
-
(1999)
Oncology
, vol.57
, pp. 138-142
-
-
Takanami, I.1
Takeuchi, K.2
Kodaira, S.3
-
27
-
-
0034650795
-
Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: possible involvement of TNFalpha and IL-1alpha
-
Torisu H., Ono M., Kiryu H., Furue M., Ohmoto Y., Nakayama J., et al. Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: possible involvement of TNFalpha and IL-1alpha. Int J Cancer 85 (2000) 182-188
-
(2000)
Int J Cancer
, vol.85
, pp. 182-188
-
-
Torisu, H.1
Ono, M.2
Kiryu, H.3
Furue, M.4
Ohmoto, Y.5
Nakayama, J.6
-
28
-
-
33747602354
-
Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis
-
Nozawa H., Chiu C., and Hanahan D. Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis. Proc Natl Acad Sci U S A 103 33 (2006) 12493-12498
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.33
, pp. 12493-12498
-
-
Nozawa, H.1
Chiu, C.2
Hanahan, D.3
-
29
-
-
0033939222
-
Endoglin expression as a measure of microvessel density in cervical cancer
-
Brewer C.A., Setterdahl J.J., Li M.J., Johnston J.M., Mann J.L., and McAsey M.E. Endoglin expression as a measure of microvessel density in cervical cancer. Obstet Gynecol 96 (2000) 224-228
-
(2000)
Obstet Gynecol
, vol.96
, pp. 224-228
-
-
Brewer, C.A.1
Setterdahl, J.J.2
Li, M.J.3
Johnston, J.M.4
Mann, J.L.5
McAsey, M.E.6
-
30
-
-
0030777860
-
Angiogenesis is associated with vascular endothelial growth factor expression in cervical intraepithelial neoplasia
-
Dobbs S.P., Hewett P.W., Johnson I.R., Carmichael J., and Murray J.C. Angiogenesis is associated with vascular endothelial growth factor expression in cervical intraepithelial neoplasia. Br J Cancer 76 (1997) 1410-1415
-
(1997)
Br J Cancer
, vol.76
, pp. 1410-1415
-
-
Dobbs, S.P.1
Hewett, P.W.2
Johnson, I.R.3
Carmichael, J.4
Murray, J.C.5
-
31
-
-
0027958101
-
Demonstration and characterization of the angiogenic properties of cervical dysplasia
-
Smith-McCune K.K., and Weidner N. Demonstration and characterization of the angiogenic properties of cervical dysplasia. Cancer Res 54 (1994) 800-804
-
(1994)
Cancer Res
, vol.54
, pp. 800-804
-
-
Smith-McCune, K.K.1
Weidner, N.2
-
32
-
-
33646034061
-
Angiogenesis in cervical intraepithelial neoplasia and early-staged uterine cervical squamous cell carcinoma: clinical significance
-
Triratanachat S., Niruthisard S., Trivijitsilp P., Tresukosol D., and Jarurak N. Angiogenesis in cervical intraepithelial neoplasia and early-staged uterine cervical squamous cell carcinoma: clinical significance. Int J Gynecol Cancer 16 (2006) 575-580
-
(2006)
Int J Gynecol Cancer
, vol.16
, pp. 575-580
-
-
Triratanachat, S.1
Niruthisard, S.2
Trivijitsilp, P.3
Tresukosol, D.4
Jarurak, N.5
-
33
-
-
18744392525
-
CD34 as a marker for evaluating angiogenesis in cervical cancer
-
Vieira S.C., Silva B.B., Pinto G.A., Vassallo J., Moraes N.G., Santana J.O., et al. CD34 as a marker for evaluating angiogenesis in cervical cancer. Pathol Res Pract 201 (2005) 313-318
-
(2005)
Pathol Res Pract
, vol.201
, pp. 313-318
-
-
Vieira, S.C.1
Silva, B.B.2
Pinto, G.A.3
Vassallo, J.4
Moraes, N.G.5
Santana, J.O.6
-
34
-
-
1842425424
-
Quantification of angiogenesis in cervical cancer: a comparison among three endothelial cell markers
-
Vieira S.C., Zeferino L.C., Da Silva B.B., Aparecida Pinto G., Vassallo J., Carasan G.A., et al. Quantification of angiogenesis in cervical cancer: a comparison among three endothelial cell markers. Gynecol Oncol 93 (2004) 121-124
-
(2004)
Gynecol Oncol
, vol.93
, pp. 121-124
-
-
Vieira, S.C.1
Zeferino, L.C.2
Da Silva, B.B.3
Aparecida Pinto, G.4
Vassallo, J.5
Carasan, G.A.6
-
35
-
-
0037222076
-
Presence and quantification of macrophages in squamous cell carcinoma of the cervix
-
Heller D.S., Hameed M., Cracchiolo B., Wiederkehr M., Scott D., Skurnick J., et al. Presence and quantification of macrophages in squamous cell carcinoma of the cervix. Int J Gynecol Cancer 13 (2003) 67-70
-
(2003)
Int J Gynecol Cancer
, vol.13
, pp. 67-70
-
-
Heller, D.S.1
Hameed, M.2
Cracchiolo, B.3
Wiederkehr, M.4
Scott, D.5
Skurnick, J.6
-
36
-
-
0029133938
-
Inverse modulation of intraepithelial Langerhans' cells and stromal macrophage/dendrocyte populations in human papillomavirus-associated squamous intraepithelial lesions of the cervix
-
al-Saleh W., Delvenne P., Arrese J.E., Nikkels A.F., Pierard G.E., and Boniver J. Inverse modulation of intraepithelial Langerhans' cells and stromal macrophage/dendrocyte populations in human papillomavirus-associated squamous intraepithelial lesions of the cervix. Virchows Arch 427 (1995) 41-48
-
(1995)
Virchows Arch
, vol.427
, pp. 41-48
-
-
al-Saleh, W.1
Delvenne, P.2
Arrese, J.E.3
Nikkels, A.F.4
Pierard, G.E.5
Boniver, J.6
-
37
-
-
0032984550
-
Macrophage infiltration and angiogenesis in cervical squamous cell carcinoma-clinicopathologic correlation
-
Davidson B., Goldberg I., Gotlieb W.H., Lerner-Geva L., Ben-Baruch G., and Agulansky L. Macrophage infiltration and angiogenesis in cervical squamous cell carcinoma-clinicopathologic correlation. Acta Obstet Gynecol Scand 78 (1999) 240-244
-
(1999)
Acta Obstet Gynecol Scand
, vol.78
, pp. 240-244
-
-
Davidson, B.1
Goldberg, I.2
Gotlieb, W.H.3
Lerner-Geva, L.4
Ben-Baruch, G.5
Agulansky, L.6
-
38
-
-
0030865035
-
Inflammatory response in cervical intraepithelial neoplasia and squamous cell carcinoma of the uterine cervix
-
Davidson B., Goldberg I., and Kopolovic J. Inflammatory response in cervical intraepithelial neoplasia and squamous cell carcinoma of the uterine cervix. Pathol Res Pract 193 (1997) 491-495
-
(1997)
Pathol Res Pract
, vol.193
, pp. 491-495
-
-
Davidson, B.1
Goldberg, I.2
Kopolovic, J.3
-
39
-
-
0029864222
-
Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice
-
Arbeit J.M., Howley P.M., and Hanahan D. Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice. Proc Natl Acad Sci U S A 93 (1996) 2930-2935
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 2930-2935
-
-
Arbeit, J.M.1
Howley, P.M.2
Hanahan, D.3
-
40
-
-
0029844435
-
Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice
-
Coussens L.M., Hanahan D., and Arbeit J.M. Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice. Am J Pathol 149 (1996) 1899-1917
-
(1996)
Am J Pathol
, vol.149
, pp. 1899-1917
-
-
Coussens, L.M.1
Hanahan, D.2
Arbeit, J.M.3
-
41
-
-
0033151608
-
Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis
-
Coussens L.M., Raymond W.W., Bergers G., Laig-Webster M., Behrendtsen O., and Werb Z. Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. Genes Dev 13 (1999) 1382-1397
-
(1999)
Genes Dev
, vol.13
, pp. 1382-1397
-
-
Coussens, L.M.1
Raymond, W.W.2
Bergers, G.3
Laig-Webster, M.4
Behrendtsen, O.5
Werb, Z.6
-
42
-
-
4944239035
-
An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis
-
Giraudo E., Inoue M., and Hanahan D. An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis. J Clin Invest 114 (2004) 623-633
-
(2004)
J Clin Invest
, vol.114
, pp. 623-633
-
-
Giraudo, E.1
Inoue, M.2
Hanahan, D.3
-
43
-
-
0027975453
-
Nitric oxide: a physiologic messenger molecule
-
Bredt D.S., and Snyder S.H. Nitric oxide: a physiologic messenger molecule. Annu Rev Biochem 63 (1994) 175-195
-
(1994)
Annu Rev Biochem
, vol.63
, pp. 175-195
-
-
Bredt, D.S.1
Snyder, S.H.2
-
44
-
-
0028092958
-
Nitric oxide synthases: roles, tolls, and controls
-
Nathan C., and Xie Q.W. Nitric oxide synthases: roles, tolls, and controls. Cell 78 (1994) 915-918
-
(1994)
Cell
, vol.78
, pp. 915-918
-
-
Nathan, C.1
Xie, Q.W.2
-
45
-
-
0029079394
-
Roles of nitric oxide in tumor growth
-
Jenkins D.C., Charles I.G., Thomsen L.L., Moss D.W., Holmes L.S., Baylis S.A., et al. Roles of nitric oxide in tumor growth. Proc Natl Acad Sci U S A 92 (1995) 4392-4396
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 4392-4396
-
-
Jenkins, D.C.1
Charles, I.G.2
Thomsen, L.L.3
Moss, D.W.4
Holmes, L.S.5
Baylis, S.A.6
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