In vitro EROD induction equivalency factors for the 10 PAHs generally monitored in risk assessment studies in the Netherlands

Chemosphere

Volumn 49, Issue 1, 2002, Pages 75-83

  Bosveld, Albertus T C ^a   De Bie, Paul A F ^a   Van den Brink, Nico W ^a   Jongepier, Hester ^a   Klomp, Anette V ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Anthracene; Benz a anthracene, Chrysene; Benzo a pyrene; Benzo g,h,i perylene, and indeno 1,2,3 cd pyrene; Benzo k fluoranthene; Fluoranthene; H4IIE; Naphthalene; Phenanthrene; Polycyclic aromatic hydrocarbons; TEF

Indexed keywords

BIOASSAY; NUTRITION; RISK ASSESSMENT;

HUMAN DIET;

POLYCYCLIC AROMATIC HYDROCARBONS;

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ANTHRACENE; BENZ[A]ANTHRACENE; BENZO[A]PYRENE; BENZO[GHI]PERYLENE; BENZO[K]FLUORANTHENE; CHRYSENE; ETHOXYRESORUFIN DEETHYLASE; FLUORANTHENE; INDENO[1,2,3 CD]PYRENE; NAPHTHALENE; PHENANTHRENE; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG; CHOLINERGIC RECEPTOR; CYTOCHROME P450 1A1;

BIOASSAY; PAH; POLLUTION INCIDENCE; RISK ASSESSMENT;

ANIMAL CELL; ARTICLE; BIOASSAY; CONCENTRATION RESPONSE; ENVIRONMENTAL MONITORING; ENZYME ACTIVITY; ENZYME INDUCTION; MEASUREMENT; NETHERLANDS; NONHUMAN; RAT; RISK ASSESSMENT; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; DIET; DOSE RESPONSE; DRUG EFFECT; HUMAN; METABOLISM; METHODOLOGY; TOXICITY TESTING;

ANIMAL; CELLS, CULTURED; CYTOCHROME P-450 CYP1A1; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL MONITORING; HUMAN; MODELS, BIOLOGICAL; NETHERLANDS; POLYCYCLIC HYDROCARBONS, AROMATIC; RATS; RECEPTORS, CHOLINERGIC; RISK ASSESSMENT; TOXICITY TESTS; ANIMALS; HUMANS;

NETHERLANDS;

FORMICIDAE;

EID: 0036771751     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0045-6535(02)00161-3     Document Type: Article

References (22)

1. Ability of polycyclic aromatic compounds to induce 7-ethoxyresorufin-O-deethylase activity in a trout liver cell line
2. Toxicity and EROD-inducing potency of 24 polycyclic aromatic hydrocarbons (PAHs) in chick embryos
3. Synergistic activity of polynuclear aromatic hydrocarbon mixtures as aryl hydrocarbon (Ah) receptor agonists
4. Toxic equivalency factor approach for risk assessment of polycyclic aromatic hydrocarbons
5. Cytochrome P4501 A induction potencies of polycyclic aromatic hydrocarbons in a fish hepastoma cell line: Demonstration of additive interactions
6. Comparison of arylhydrocarbon hydroxylase and acetanillide 4-hydroxylase induction by polycyclic aromatic compounds in human and mouse cell lines
7. Polycyclic aromatic hydrocarbon contamination in the Italian diet
8. Induction effects of polychlorinated biphenyls, polycyclic aromatic hydrocarbons and other widespread aromatic environmental pollutants on microsomal monooxygenase activities in chick embryo liver
9. Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay
10. Toxic equivalency factors (TEHs) for polycyclic aromatic hydrocarbons (PAHs)
11. The cytosolic receptor binding affinities and AHH induction potencies of 29 polynuclear aromatic hydrocarbons
12. Development and validation of in vitro induction assay for toxic halogenated aromatic mixtures: A review
13. Polychlorinated Biphenyls (PCBs) dibenzo-p-dioxins (PCDDs) dibenzofurans (PCDFs) and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalence factors (TEFs)
14. Effect of polycyclic aromatic hydrocarbons on hepatic microsomal enzymes and disposition of methyl-naphtalene in rainbow trout in vivo
15. Potency of various polycyclic aromatic hydrocarbons as inducers of CYP1A1 in rat hepatocyte cultures
16. H4IIE rat hepatoma cell bioassay-derived 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents in colonial fish-eating waterbird eggs from the Great Lakes
17. Characterization of TCDD-receptor ligands present in extracts of urban particulate matter
18. Interactive effects on the EROD inducing potency of polyhalogenated aromatic hydrocarbons in the chicken embryo hepatocyte assay
19. Characterization of the H4IIE rat hepatoma cell bioassay for evaluation of environmental samples containing polynuclear aromatic hydrocarbons (PAHs)