Contributions of a highly conserved V(H)/V(L) hydrogen bonding interaction to scFv folding stability and refolding efficiency

Biophysical Journal

Volumn 75, Issue 3, 1998, Pages 1473-1482

  Tan, Philip H ^a   Sandmaier, Brenda M ^b   Stayton, Patrick S ^a  

^a University of Washington   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIBODY STRUCTURE; ARTICLE; HYDROGEN BOND; NONHUMAN; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ANIMALIA;

EID: 0031660079     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(98)74066-4     Document Type: Article

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