-
1
-
-
0037672877
-
Philadelphia chromosome-positive leukemias: From basic mechanisms to molecular therapeutics
-
Kurzrock R, Kantarjian HM, Druker BJ, Talpaz M. Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics. Ann. Intern. Med. 138, 819-830 (2003).
-
(2003)
Ann. Intern. Med
, vol.138
, pp. 819-830
-
-
Kurzrock, R.1
Kantarjian, H.M.2
Druker, B.J.3
Talpaz, M.4
-
2
-
-
32844461437
-
Chronic myeloid leukemia: Why does it evolve from chronic phase to blast transformation?
-
Mughal TI, Goldman JM. Chronic myeloid leukemia: why does it evolve from chronic phase to blast transformation? Front. Biosci. 11, 198-208 (2006).
-
(2006)
Front. Biosci
, vol.11
, pp. 198-208
-
-
Mughal, T.I.1
Goldman, J.M.2
-
3
-
-
0036435579
-
Cytogenetic and molecular genetic aspects of chronic myeloid leukaemia
-
Barnes DJ, Melo JV. Cytogenetic and molecular genetic aspects of chronic myeloid leukaemia. Acta Haematol. 108, 180-202 (2002).
-
(2002)
Acta Haematol
, vol.108
, pp. 180-202
-
-
Barnes, D.J.1
Melo, J.V.2
-
4
-
-
1142287358
-
Clinical and epidemiologic burden of chronic myelogenous leukemia
-
Redaelli A, Bell C, Casagrande J et al. Clinical and epidemiologic burden of chronic myelogenous leukemia. Expert Rev. Anticancer Ther. 4, 85-96 (2004).
-
(2004)
Expert Rev. Anticancer Ther
, vol.4
, pp. 85-96
-
-
Redaelli, A.1
Bell, C.2
Casagrande, J.3
-
5
-
-
0036341295
-
Recent approaches in acute lymphoblastic leukemia in adults
-
Gökbuget N, Hoelzer D. Recent approaches in acute lymphoblastic leukemia in adults. Rev. Clin. Erp. Hematol. 6, 114-141 (2002).
-
(2002)
Rev. Clin. Erp. Hematol
, vol.6
, pp. 114-141
-
-
Gökbuget, N.1
Hoelzer, D.2
-
7
-
-
33747154547
-
Evolving concepts in the management of chronic myeloid leukemia. Recommendations from an expert panel on behalf of the European Leukemianet
-
Baccarani M, SagliO, G, Goldman J et al. Evolving concepts in the management of chronic myeloid leukemia. Recommendations from an expert panel on behalf of the European Leukemianet. Blood 108, 1809-1820 (2006).
-
(2006)
Blood
, vol.108
, pp. 1809-1820
-
-
Baccarani, M.1
SagliO, G.2
Goldman, J.3
-
8
-
-
34249664406
-
Drug treatment is superior to allografting as first line therapy in chronic myeloid leukemia
-
Hehlmann R, Berger U, Pfirrmann M et al. Drug treatment is superior to allografting as first line therapy in chronic myeloid leukemia. Blood 109, 4686-4692 (2007).
-
(2007)
Blood
, vol.109
, pp. 4686-4692
-
-
Hehlmann, R.1
Berger, U.2
Pfirrmann, M.3
-
9
-
-
21144451094
-
In vitro activity of Bcr-AbI inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants
-
Hare T, Walters DK, Stoffregen EP et al. In vitro activity of Bcr-AbI inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants. Cancer Res. 65, 4500-4505 (2005).
-
(2005)
Cancer Res
, vol.65
, pp. 4500-4505
-
-
Hare, T.1
Walters, D.K.2
Stoffregen, E.P.3
-
10
-
-
33846847772
-
Resistance to targeted therapy in chronic myelogenous leukemia
-
Hochhaus A, Erben P, Ernst T, Mueller MC. Resistance to targeted therapy in chronic myelogenous leukemia. Semin. Hematol. 44, 15-24 (2007).
-
(2007)
Semin. Hematol
, vol.44
, pp. 15-24
-
-
Hochhaus, A.1
Erben, P.2
Ernst, T.3
Mueller, M.C.4
-
11
-
-
79959308232
-
Loss of response to imatinib: Mechanisms and management
-
Shah NP. Loss of response to imatinib: mechanisms and management. Hematology Am. Soc. Hematol. Educ. Program 183-187 (2005).
-
(2005)
Hematology Am. Soc. Hematol. Educ. Program
, vol.183-187
-
-
Shah, N.P.1
-
12
-
-
10744233716
-
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
-
O'Brien SG, Guilhot F, Larson RA et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N. Engl. J. Med. 348, 994-1004 (2003).
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 994-1004
-
-
O'Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
-
13
-
-
37049028176
-
Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity. Higher doses of imatinib may overcome the negative impact of low OCT-1 activity
-
DOI:10.1182/blood-2007-06-093617
-
White DL, Saunders VA, Dang P et al. Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity. Higher doses of imatinib may overcome the negative impact of low OCT-1 activity. Blood DOI:10.1182/blood-2007-06-093617 (2007).
-
(2007)
Blood
-
-
White, D.L.1
Saunders, V.A.2
Dang, P.3
-
14
-
-
37349061332
-
A Phase II study of nilotinib, a novel tyrosine kinase inhibitor administered to imatinib-resistant and -intolerant patients with Philadelphia-positive chronic myelogenous; leukemia in chronic phase
-
Martinelli G, Rosti G, le Coutre P et al. A Phase II study of nilotinib, a novel tyrosine kinase inhibitor administered to imatinib-resistant and -intolerant patients with Philadelphia-positive chronic myelogenous; leukemia in chronic phase. Heamatologica 92(Suppl. 1), 207 (2007).
-
(2007)
Heamatologica
, vol.92
, Issue.SUPPL. 1
, pp. 207
-
-
Martinelli, G.1
Rosti, G.2
le Coutre, P.3
-
15
-
-
37349112422
-
Nilotinib monotherapy in patients with imatinib-resistant or -intolerant Ph+ chronic myelogenous leukemia in blast crisis or relapsed/reft-actory-Ph+ acute lymphoblastic leukemia
-
Epub ahead of print
-
Ottman O, Larson R, Kantarjian H et al. Nilotinib monotherapy in patients with imatinib-resistant or -intolerant Ph+ chronic myelogenous leukemia in blast crisis or relapsed/reft-actory-Ph+ acute lymphoblastic leukemia. Haematologica 92 (Suppl. 1), 207 (2007) (Epub ahead of print).
-
(2007)
Haematologica
, vol.92
, Issue.SUPPL. 1
, pp. 207
-
-
Ottman, O.1
Larson, R.2
Kantarjian, H.3
-
16
-
-
37349061332
-
A Phase II study of nilotinib, a novel tyrosine kinase inhibitor administered to imatinib-resistant or -intolerant patients with Philadelphia-positive chronic myelogenous leukemia in accelerated phase
-
le Coutre P, Larson R, Kantarjian H et al. A Phase II study of nilotinib, a novel tyrosine kinase inhibitor administered to imatinib-resistant or -intolerant patients with Philadelphia-positive chronic myelogenous leukemia in accelerated phase. Haematologica 92(Suppl. 1), 207-208 (2007).
-
(2007)
Haematologica
, vol.92
, Issue.SUPPL. 1
, pp. 207-208
-
-
le Coutre, P.1
Larson, R.2
Kantarjian, H.3
-
17
-
-
37349059598
-
Bosutinib (SKI-606) exhibits clinical activity in patients with philadelphia chromosome positive CML or ALL who failed imatinib
-
Bruemmendorf T, Cortes J, Kantaryan H et al. Bosutinib (SKI-606) exhibits clinical activity in patients with philadelphia chromosome positive CML or ALL who failed imatinib. Haematologica 92(Suppl. 1), 116 (2007).
-
(2007)
Haematologica
, vol.92
, Issue.SUPPL. 1
, pp. 116
-
-
Bruemmendorf, T.1
Cortes, J.2
Kantaryan, H.3
-
18
-
-
39049164641
-
A Phase I study of INNO-406, a dual inhibitor of Ab1 and Lyn kinases, in adult patients with Philadelphia chromosome positive (Ph+) chronic myelogenous leukemia (CML) or acute lymphocytic leukemia (ALL) relapsed, refractory, or intolerant of imatinib
-
S
-
Craig AR, Kantarjian HM, Cortes JE et al. A Phase I study of INNO-406, a dual inhibitor of Ab1 and Lyn kinases, in adult patients with Philadelphia chromosome positive (Ph+) chronic myelogenous leukemia (CML) or acute lymphocytic leukemia (ALL) relapsed, refractory, or intolerant of imatinib. J. Clin. Oncol. 25(Suppl. 18), S368 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.SUPPL. 18
, pp. 368
-
-
Craig, A.R.1
Kantarjian, H.M.2
Cortes, J.E.3
-
19
-
-
37349040325
-
-
Gleevec ®, prescribing information. Novartis Pharmaceuticals, NJ, USA (2007)
-
Gleevec ®, prescribing information. Novartis Pharmaceuticals, NJ, USA (2007)
-
-
-
-
20
-
-
37349112660
-
-
Sprycel® prescribing information. Bristol-Myers Squibb, NY, USA (2007).
-
Sprycel® prescribing information. Bristol-Myers Squibb, NY, USA (2007).
-
-
-
-
21
-
-
33745283618
-
The structure of dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants
-
Tokarski JS, Newitt JA, Chang CY et al. The structure of dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants. Cancer Res. 66, 5790-5797 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 5790-5797
-
-
Tokarski, J.S.1
Newitt, J.A.2
Chang, C.Y.3
-
22
-
-
3142676436
-
Overriding imatinib resistance with a novel ABL kinase inhibitor
-
Shah NP, Tran C, Lee FY et al. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 305, 399-401 (2004).
-
(2004)
Science
, vol.305
, pp. 399-401
-
-
Shah, N.P.1
Tran, C.2
Lee, F.Y.3
-
23
-
-
37349005461
-
Centrosome aberrations, disturbed mitotic spindle formation and G1 arrest in normal and leukemic cells treated with the SRC/ABL inhibitor dasatinib
-
Fabarius A, Giehl M, Kraemer A et al. Centrosome aberrations, disturbed mitotic spindle formation and G1 arrest in normal and leukemic cells treated with the SRC/ABL inhibitor dasatinib. Blood 108, 614a-615a (2006).
-
(2006)
Blood
, vol.108
-
-
Fabarius, A.1
Giehl, M.2
Kraemer, A.3
-
24
-
-
33745243692
-
Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival
-
Song L, Morris M, Bagui T et al. Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival. Cancer Res. 66, 5542-5548 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 5542-5548
-
-
Song, L.1
Morris, M.2
Bagui, T.3
-
25
-
-
33745102555
-
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
-
Taipaz M, Shah NP, Kantarjian H et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N. Engl. J. Med. 354, 2531-2541 (2006).
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 2531-2541
-
-
Taipaz, M.1
Shah, N.P.2
Kantarjian, H.3
-
26
-
-
23844515505
-
-
A Phase I study of BMS-354825 patients with imatinib-resistant and intolerant chronic phase chronic myeloid leukemia (CML, results from CA180002, 23(Suppl. 16 Pt 1) S
-
Talpaz M, Kantarjian HM, Paquette R et al. A Phase I study of BMS-354825 in patients with imatinib-resistant and intolerant chronic phase chronic myeloid leukemia (CML): results from CA180002. J. Clin. Oncol. 23(Suppl. 16 Pt 1) S564-S564 (2005).
-
(2005)
J. Clin. Oncol
-
-
Talpaz, M.1
Kantarjian, H.M.2
Paquette, R.3
-
27
-
-
33947280081
-
Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of iniatinib therapy
-
Hochhaus A, Kantadian HM, Baccarani M et al. Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of iniatinib therapy. Blood 109, 2303-2309 (2007).
-
(2007)
Blood
, vol.109
, pp. 2303-2309
-
-
Hochhaus, A.1
Kantadian, H.M.2
Baccarani, M.3
-
28
-
-
37149036111
-
Dasatinib induces durable cytogenetic responses in patients with chronic-phase CML with resistance or intolerance to imatinib: Updated results of the CA180013 (START-C) trial
-
Guilhot F, Apperley J, Facon T et al. Dasatinib induces durable cytogenetic responses in patients with chronic-phase CML with resistance or intolerance to imatinib: updated results of the CA180013 (START-C) trial. Haematologica 92(Suppl. 1), 128 (2007).
-
(2007)
Haematologica
, vol.92
, Issue.SUPPL. 1
, pp. 128
-
-
Guilhot, F.1
Apperley, J.2
Facon, T.3
-
29
-
-
34248324467
-
Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in accelerated phase
-
Guilbot F, Apperiey J, Kim DW et al. Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in accelerated phase. Blood 109, 4143-4150 (2007).
-
(2007)
Blood
, vol.109
, pp. 4143-4150
-
-
Guilbot, F.1
Apperiey, J.2
Kim, D.W.3
-
30
-
-
34247543905
-
Dasatinib (SPRYCEL) in patients (pts) with chronic myelogenous leukemia in accelerated phase (AP-CML) that is imatinib-resistant (im-r) or -intolerant (im-i): Updated results of the CA 180-005 START-A Phase II study
-
Cortes J, Kim DW, Gullhot F et al. Dasatinib (SPRYCEL) in patients (pts) with chronic myelogenous leukemia in accelerated phase (AP-CML) that is imatinib-resistant (im-r) or -intolerant (im-i): updated results of the CA 180-005 START-A Phase II study. Blood 108, 613a (2006).
-
(2006)
Blood
, vol.108
-
-
Cortes, J.1
Kim, D.W.2
Gullhot, F.3
-
31
-
-
33947356135
-
Dasatinib induces complete hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in blast crisis
-
Cortes J, Rousseiot P, Kim DW et al. Dasatinib induces complete hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in blast crisis. Blood 109, 3207-3213 (2007).
-
(2007)
Blood
, vol.109
, pp. 3207-3213
-
-
Cortes, J.1
Rousseiot, P.2
Kim, D.W.3
-
32
-
-
33846819360
-
Dasatinib (SPRYCEL) efficacy and safety in patients (pts) with chronic myelogenous leukemia in lymphoid (CML-LB) or myeloid blast (CML-MB) phase who are imatinib-resistant (im-r) or -intolerant (im-i)
-
Martinelli G, Hochhaus A, Coutre S et al. Dasatinib (SPRYCEL) efficacy and safety in patients (pts) with chronic myelogenous leukemia in lymphoid (CML-LB) or myeloid blast (CML-MB) phase who are imatinib-resistant (im-r) or -intolerant (im-i). Blood 108, 224a (2006).
-
(2006)
Blood
, vol.108
-
-
Martinelli, G.1
Hochhaus, A.2
Coutre, S.3
-
33
-
-
34948829146
-
Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: Interim results of a Phase II study
-
Ottmann O, Dombret H, Martinelli G et al. Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: interim results of a Phase II study. Blood 110(7), 2309-2315 (2007).
-
(2007)
Blood
, vol.110
, Issue.7
, pp. 2309-2315
-
-
Ottmann, O.1
Dombret, H.2
Martinelli, G.3
-
34
-
-
37349069514
-
-
Ottmann O, Hochhaus A, Saglio G et al. Dasatinib induces rapid and durable responses in patients with Ph+ ALL resistant or intolerant to imatimb: updated results from CA180015 (START-L) trial. Haematolooca 92 (Suppi. 1), 9-10 (2007).
-
Ottmann O, Hochhaus A, Saglio G et al. Dasatinib induces rapid and durable responses in patients with Ph+ ALL resistant or intolerant to imatimb: updated results from CA180015 (START-L) trial. Haematolooca 92 (Suppi. 1), 9-10 (2007).
-
-
-
-
35
-
-
34249074686
-
Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia after failure of first-line imatinib: A randomized Phase 2 trial
-
Kantarjian H, Pasquini R, Hamerschlak N et al. Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia after failure of first-line imatinib: a randomized Phase 2 trial. Blood 109, 5143-5150 (2007).
-
(2007)
Blood
, vol.109
, pp. 5143-5150
-
-
Kantarjian, H.1
Pasquini, R.2
Hamerschlak, N.3
-
36
-
-
37349126943
-
Dasatinib is safe and effective in patients with previously untreated chronic myelogenous leukemia in chronic phase
-
Quintas-Cardama A, Kantarjian H, O'Brien S et al. Dasatinib is safe and effective in patients with previously untreated chronic myelogenous leukemia in chronic phase. Haematologica 92 (Suppl. 1), 129 (2007).
-
(2007)
Haematologica
, vol.92
, Issue.SUPPL. 1
, pp. 129
-
-
Quintas-Cardama, A.1
Kantarjian, H.2
O'Brien, S.3
-
37
-
-
37149031172
-
Dasatinib dose and schedule optimization in chronic-phase CML resistant or intolerant to imatinib: Results from a randomized Phase-III trial (CA180034)
-
Hochhaus A, Kim DW, Rousselot P et al. Dasatinib dose and schedule optimization in chronic-phase CML resistant or intolerant to imatinib: results from a randomized Phase-III trial (CA180034). Haematoloogica 92(Suppl. 1), 128-129 (2007).
-
(2007)
Haematoloogica
, vol.92
, Issue.SUPPL. 1
, pp. 128-129
-
-
Hochhaus, A.1
Kim, D.W.2
Rousselot, P.3
-
38
-
-
37349115522
-
Dasatinib 140 mg QD vs 70 mg bid in advanced-phase CML or Ph(+) ALL resistant or intolerant to imatinib: Results from a randomized, Phase-III trial (CA180035)
-
Dombret H, Ottmann OG, Gob Y et al. Dasatinib 140 mg QD vs 70 mg bid in advanced-phase CML or Ph(+) ALL resistant or intolerant to imatinib: results from a randomized, Phase-III trial (CA180035). Haematologica 92 (Suppl. 1), 319 (2007).
-
(2007)
Haematologica
, vol.92
, Issue.SUPPL. 1
, pp. 319
-
-
Dombret, H.1
Ottmann, O.G.2
Gob, Y.3
-
39
-
-
37349092298
-
Efficacy of dasatinib in chronic phase chronic myelogenous leukemia patients after imatinib failure according to baseline BCR-ABL mutations
-
Mueller MC, Branford S, Radich J et al. Efficacy of dasatinib in chronic phase chronic myelogenous leukemia patients after imatinib failure according to baseline BCR-ABL mutations. Haematologica 92(Suppl. 1), 127 (2007).
-
(2007)
Haematologica
, vol.92
, Issue.SUPPL. 1
, pp. 127
-
-
Mueller, M.C.1
Branford, S.2
Radich, J.3
-
40
-
-
33748290171
-
-
Kantarjian H, Jabbour E, Grimley J, Kirkpatrick P. Dasatinib. Nat. Rev. Drug Discov. 5, 717-718 (2006).
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 717-718
-
-
Kantarjian, H.1
Jabbour, E.2
Grimley, J.3
Dasatinib, K.P.4
-
41
-
-
20944442975
-
Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate
-
Cortes J, Talpaz M, O'Brien S et al. Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate. Clin. Cancer Res. 11, 3425-3432 (2005).
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 3425-3432
-
-
Cortes, J.1
Talpaz, M.2
O'Brien, S.3
-
42
-
-
37349130542
-
-
Druker BJ, Guilhot F, O'Brien S, Larson N, on behalf of the IRIS anternational Randomized IF. Long-term benefits of imtinib (IM) for patients newly diagnosed with chronic myelogenous leukemia in chronic phase (CML-CP): the 5-year update from the IRIS study. Proc. Am. Soc. Clin. Oncol. 24, S338 (2006).
-
Druker BJ, Guilhot F, O'Brien S, Larson N, on behalf of the IRIS anternational Randomized IF. Long-term benefits of imtinib (IM) for patients newly diagnosed with chronic myelogenous leukemia in chronic phase (CML-CP): the 5-year update from the IRIS study. Proc. Am. Soc. Clin. Oncol. 24, S338 (2006).
-
-
-
-
43
-
-
0348015863
-
The early molecular response to imatinib predicts cytogenetic and clinical outcome in chronic myeloid leukaemia
-
Wang L, Pearson K, Ferguson JE, Clark RE. The early molecular response to imatinib predicts cytogenetic and clinical outcome in chronic myeloid leukaemia. Br. J. Haematol. 120, 990-999 (2003).
-
(2003)
Br. J. Haematol
, vol.120
, pp. 990-999
-
-
Wang, L.1
Pearson, K.2
Ferguson, J.E.3
Clark, R.E.4
-
44
-
-
30844433972
-
Molecular monitoring of BCR-ABL as a guide to clinical management in chronic myeloid leukaemia
-
Hughes T, Branford S. Molecular monitoring of BCR-ABL as a guide to clinical management in chronic myeloid leukaemia. Blood Rev. 20, 29-41 (2006).
-
(2006)
Blood Rev
, vol.20
, pp. 29-41
-
-
Hughes, T.1
Branford, S.2
-
45
-
-
10744230175
-
The significance of myelosuppression during therapy with imatinib mesylate in patients with chronic myelogenous leukemia in chronic phase
-
Sneed TB, Kantarjian HM, Talpaz M et al. The significance of myelosuppression during therapy with imatinib mesylate in patients with chronic myelogenous leukemia in chronic phase. Cancer 100, 116-121 (2004).
-
(2004)
Cancer
, vol.100
, pp. 116-121
-
-
Sneed, T.B.1
Kantarjian, H.M.2
Talpaz, M.3
-
46
-
-
4344672552
-
Imatinib therapy in chronic myelogenous leukemia: Strategies to avoid and overcome resistance
-
Hochhaus A, La Rosée P. Imatinib therapy in chronic myelogenous leukemia: strategies to avoid and overcome resistance. Leukemia 18, 1321-1331 (2004).
-
(2004)
Leukemia
, vol.18
, pp. 1321-1331
-
-
Hochhaus, A.1
La Rosée, P.2
-
47
-
-
0036045378
-
Insights from pre-clinical studies for new combination treatment regimens with the Bcr-Abl kinase inhibitor imatinib mesylate (Gleevec/Glivec) in chronic myelogenous leukemia: A translational perspective
-
La Rosée P, O'Dwyer ME, Druker BJ. Insights from pre-clinical studies for new combination treatment regimens with the Bcr-Abl kinase inhibitor imatinib mesylate (Gleevec/Glivec) in chronic myelogenous leukemia: a translational perspective. Leukemia 16, 1213-1219 (2002).
-
(2002)
Leukemia
, vol.16
, pp. 1213-1219
-
-
La Rosée, P.1
O'Dwyer, M.E.2
Druker, B.J.3
-
48
-
-
14744274624
-
Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance
-
Burgess MR, Skaggs BJ, Shah NP, Lee FY, Sawyers CL. Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance. Proc. Natl Acad. Sci. USA 102, 3395-3400 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 3395-3400
-
-
Burgess, M.R.1
Skaggs, B.J.2
Shah, N.P.3
Lee, F.Y.4
Sawyers, C.L.5
-
49
-
-
34247891789
-
Emerging strategies for the treatment of mutant Bcr-Abl T315I myeloid leukemia
-
Mughat TI, Goldman JM. Emerging strategies for the treatment of mutant Bcr-Abl T315I myeloid leukemia. Clin. Lymphoma Myeloma 7(Suppl. 2), S81-S84 (2007).
-
(2007)
Clin. Lymphoma Myeloma
, vol.7
, Issue.SUPPL. 2
-
-
Mughat, T.I.1
Goldman, J.M.2
-
51
-
-
33750035763
-
The clinical challenge of imatinib resistance in chronic myeloid leukemia: Emerging strategies with new targeted agents
-
Jabbour E, Cortes J, Giles F, O'Brien S, Kantarjian H. The clinical challenge of imatinib resistance in chronic myeloid leukemia: emerging strategies with new targeted agents. Targ. Oncol. 1, 186-196 (2006).
-
(2006)
Targ. Oncol
, vol.1
, pp. 186-196
-
-
Jabbour, E.1
Cortes, J.2
Giles, F.3
O'Brien, S.4
Kantarjian, H.5
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