Scalarane sesterterpenes from a marine sponge of the genus Spongia and their FXR antagonistic activity

Journal of Natural Products

Volumn 70, Issue 11, 2007, Pages 1691-1695

  Nam, Sang Jip ^a   Ko, Hyunsil ^a   Moon, Kyeong Ju ^a   Hwang, Hoosang ^a   Chin, Jungwook ^a   Ham, Jungyeob ^b   Lee, Byoungchan ^a   Lee, Jaehwan ^a   Dong, Hwan Won ^a   Choi, Hyukjae ^a   Ko, Jaeyoung ^a   Shin, Kyoungjin ^a   Oh, Taekyung ^a   Kim, Seokho ^a   Rho, Jung Rae ^c   Kang, Heonjoong ^a  

^a Seoul National University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Kunsan National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

12 O DEACETYL 12 EPI 19 DEOXY 22 HYDROXYSCALARIN; 12 O DEACETYL 12 EPI 19 DEPXY 21 HYDROXYSCALARIN; 12 O DEACETYL 12 EPI 19 O METHYLSCALARIN; FARNESOID X RECEPTOR; SESTERTERPENE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; IC 50; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; SPONGE (PORIFERA); SURFACE PLASMON RESONANCE;

ANIMALS; DNA-BINDING PROTEINS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PORIFERA; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SESTERTERPENES; TRANSCRIPTION FACTORS;

SPONGIA;

EID: 37249092686     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np070024k     Document Type: Article

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