Effect of Ganoderma lucidum on cytokine release by peritoneal macrophages

Iranian Journal of Immunology

Volumn 4, Issue 4, 2007, Pages 220-226

  Ahmadi, Kazem ^a   Riazipour, Majid ^a  

^a BAQIYATALLAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Ganoderma lucidum; Interleukin 1; Interleukin 12; Macrophage; Tumor Necrosis Factor and Nitric Oxide

Indexed keywords

CARBON DIOXIDE; GANODERMA LUCIDUM EXTRACT; INTERLEUKIN 12; INTERLEUKIN 1BETA; NITRIC OXIDE; PENICILLIN G; STREPTOMYCIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL FREE SYSTEM; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; GANODERMA LUCIDUM; INCUBATION TIME; MACROPHAGE FUNCTION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; SYNTHESIS;

EID: 37249080599     PISSN: 17351383     EISSN: 1735367X     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Peterson RR. Ganoderma - a therapeutic fungal biofactory. Phytochemistry. 2006; 67: 1985-2001.
2. Gao Y, Zhou S, Huang M, Xu A. Antibacterial and anti viral value of the genus Ganoderma. Int J Med Mush. 2003; 5: 235-46.
3. Aydemir G. Research on Nutrition and Cancer: The Importance of the Standardized Dietary Assessments. Asian Pac J Cancer Prev. 2002; 3:177-80.
4. Sliva D. Ganoderma lucidum in cancer research. Leuk Res. 2006 ;30:767-8
5. Chen X, Hu ZP, Yang XX, Huang M, Gao Y, Tang W et al. Monitoring of immune responses to a herbal immuno-modulator in patients with advanced colorectal cancer. Int Immunopharmacol. 2006; 6:499-508.
6. Song YS, Kim SH, Sa JH, Jin C, Lim CJ, Park EH. Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum. J Ethnopharmacol. 2004; 90:17-20.
7. Nonaka Y, Shibata H, Nakai M, Kurihara H, Ishibashi H, Kiso Y et al. Anti-tumor activities of the antlered form of Ganoderma lucidum in allogeneic and syngeneic tumor-bearing mice. Biosci Biotechnol Biochem. 2006; 70:2028-34.
8. Chien CM, Cheng JL, Chang WT, Tien MH, Tsao CM, Chang YH et al. Polysaccharides of Ganoderma lucidum alter cell immunophenotypic expression and enhance CD56+ NK-cell cytotoxicity in cord blood. Bioorg Med Chem. 2004; 12:5603-9.
9. Zhu XL, Chen AF, Lin ZB. Ganoderma lucidum polysaccharides enhance the function of immunological effector cells in immunosuppressed mice. Journal of Ethnopharmacology, 2007; 111: 219-26.
10. Kohguchi M, Kunikata T, Watanabe H, Kudo N, Shibuya T, Ishihara T et al. Immuno-potentiating effects of the antler-shaped fruiting body of Ganoderma lucidum (Rokkaku-Reishi). Biosci Biotechnol Biochem. 2004; 68:881-7.
11. Kuo MC, Weng CY, Ha CL, Wu MJ. Ganoderma lucidum mycelia enhance innate immunity by activating NF-kappaB. J Ethnopharmacol. 2006; 103:217-22.
12. Lin JY, Chen ML, Lin BF. Ganoderma tsugae in vivo modulates Th1/Th2 and macrophage responses in an allergic murine model. Food Chem Toxicol. 2006; 44:2025-32.
13. Hsu HY, Hua KF, Lin CC, Lin CH, Hsu J, Wong CH. Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways. J Immunol. 2004; 173:5989-99.
14. Johnstone A, Thorpe R. Immunochemistry in practice. 3rd ed. Black Well Science; 1996.
15. Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR. Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids. Anal Biochem. 1982; 126:131-8.
16. Wang SY, Hsu ML, Hsu HC, Tzeng CH, Lee SS, Shiao MS et al. The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes. Int J Cancer. 1997; 70:699-705.
17. Wang G, Zhao J, Liu J, Huang Y, Zhong JJ, Tang W. Enhancement of IL-2 and IFN-gamma expression and NK cells activity involved in the anti-tumor effect of ganoderic acid Me in vivo. Int Immunopharmacol. 2007; 7:864-70.
18. Gao Y, Gao H, Chan E, Tang W, Xu A, Yang H et al. Antitumor activity and underlying mechanisms of ganopoly, the refined polysaccharides extracted from Ganoderma lucidum, in mice. Immunol Invest. 2005; 34:171-98.
19. Gao YH, Zhou SF. The immunomodulating effects of Ganoderma lucidum. Int J Med Mush. 2002; 4: 1-11.
20. Chen HS, Tsai YF, Lin S, Lin CC, Khoo KH, Lin CH et al. Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides. Bioorg Med Chem. 2004; 12:5595-601.
21. Berovic M, Habijanic J, Zore I, Wraber B, Hodzar D, Boh B et al. Submerged cultivation of Ganoderma lucidum biomass and immunostimulatory effects of fungal polysaccharides. J Biotechnol. 2003; 103:77-86.
22. Wang YY, Khoo KH, Chen ST, Lin CC, Wong CH, Lin CH. Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities. Bioorg Med Chem. 2002; 10:1057-62.
23. Suzuki I, Tanaka H, Kinoshita A, Oikawa S, Osawa M, Yadomae T. Effect of orally administered beta-glucan on macrophage function in mice. Int J Immunopharmacol. 1990; 12:675-84.
24. Ahmadi-Renani K, McCruden AB. Five alpha dihydrotestosterone (5a-DHT) may modulate nitric oxide via endogenous cytokines. Medical Journal of the Islamic republic of Iran. 1999; 13: 207-11.