Pharmacokinetics and clinical efficacy of lorazepam in children with severe malaria and convulsions

British Journal of Clinical Pharmacology

Volumn 65, Issue 1, 2008, Pages 12-21

  Muchohi, Simon N ^a,g   Obiero, Kenneth ^b   Newton, Charles R J C ^a,c   Ogutu, Bernhards R ^b   Edwards, Geoffrey ^d,e   Kokwaro, Gilbert O ^a,f  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b U S ARMY   (United States)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF LIVERPOOL   (United Kingdom)

^e LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^f UNIVERSITY OF NAIROBI   (Kenya)

^g KEMRI WELLCOME TRUST RESEARCH PROGRAMME   (Kenya)

Author keywords

Children; Convulsions; Lorazepam; Malaria; Pharmacokinetics

Indexed keywords

AMODIAQUINE; CHLORAMPHENICOL; DIAZEPAM; DIHYDROARTEMISININ; LORAZEPAM; PARACETAMOL; PENICILLIN G; PHENOBARBITAL; QUININE;

ADOLESCENT; AREA UNDER THE CURVE; ARTICLE; BACTEREMIA; BLOOD SAMPLING; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARTMENT MODEL; CONFIDENCE INTERVAL; CONVULSION; DISEASE DURATION; DISEASE SEVERITY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG FATALITY; FEMALE; HUMAN; INFANT; LOADING DRUG DOSE; MALARIA; MALE; MENINGITIS; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RECURRENT DISEASE; SEIZURE; SINGLE DRUG DOSE;

AFRICA; ANTICONVULSANTS; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAVENOUS; LORAZEPAM; MALARIA; MALE; RURAL HEALTH; SEIZURES; STATISTICS AS TOPIC;

EID: 37249065696     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2007.02966.x     Document Type: Article

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