Determination of lorazepam in plasma from children by high-performance liquid chromatography with UV detection

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 824, Issue 1-2, 2005, Pages 333-340

  Muchohi, Simon N ^a,b   Obiero, Kenneth ^c   Kokwaro, Gilbert O ^a,b,d   Ogutu, Bernhards R ^c   Githiga, Isaiah M ^d   Edwards, Geoffrey ^e,f   Newton, Charles R J C ^b,g  

^a KEMRI WELLCOME TRUST RESEARCH PROGRAMME   (Kenya)

^b KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^c New Nyanza Provincial General Hospital   (Kenya)

^d UNIVERSITY OF NAIROBI   (Kenya)

^e LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^f UNIVERSITY OF LIVERPOOL   (United Kingdom)

^g UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Analysis in plasma; Children; High performance liquid chromatography; Lorazepam; Pharmacokinetics

Indexed keywords

BIOASSAY; CONCENTRATION (PROCESS); DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHARMACOKINETICS; PLASMAS; SEPARATION; SOLVENT EXTRACTION;

ANALYSIS IN PLASMA; CHILDREN; LORAZEPAM; OXAZEPAM (OZP);

ULTRAVIOLET DETECTORS;

ACETONITRILE; ANALGESIC AGENT; ANTICONVULSIVE AGENT; ANTIINFECTIVE AGENT; ANTIMALARIAL AGENT; ANTIPYRETIC AGENT; ARTESUNATE; BUFFER; CHLORAMPHENICOL; CHLORAMPHENICOL HEMISUCCINATE; CHLOROQUINE; CYCLOGUANIL; DIAZEPAM; DICHLOROMETHANE; FOSPHENYTOIN SODIUM; GENTAMICIN; HEXANE; LORAZEPAM; MIDAZOLAM; OXAZEPAM; PARACETAMOL; PENICILLIN G; PHENOBARBITAL; PHENYTOIN; POTASSIUM DERIVATIVE; PROGUANIL; PYRIMETHAMINE; QUININE; SALICYLIC ACID; SULFADOXINE;

ACCURACY; ALKALINITY; ARTICLE; CALIBRATION; CHILD; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; FLOW RATE; HUMAN; LIQUID LIQUID EXTRACTION; PARTICLE SIZE; PRIORITY JOURNAL; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET RADIATION;

ANTICONVULSANTS; CALIBRATION; CHILD; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; INJECTIONS, INTRAVENOUS; LORAZEPAM; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ULTRAVIOLET;

ARTESUNATE; CINCHONA PUBESCENS;

EID: 24044440115     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.07.040     Document Type: Article

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