Expression pattern of p63 in oral epithelial lesions and submucous fibrosis associated with betel-quid chewing in Sri Lanka

Medical Molecular Morphology

Volumn 40, Issue 4, 2007, Pages 203-207

  Haniffa, Abusayeed M ^a   Saitoh, Masato ^b   Abiko, Yoshihiro ^b   Takeshima, Maiko ^b   Nishimura, Michiko ^b   Yamazaki, Mami ^b   Nagayasu, Hiroki ^b   Sugiura, Chihiro ^c   Muthumala, Malantha ^d   Kaku, Tohru ^b   Chiba, Itsuo ^b   Shibata, Toshiyuki ^e  

^a Office of Deputy Provincial Director of Health Services   (Sri Lanka)

^b HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d General Hospital Kalutara   (Sri Lanka)

^e GIFU UNIVERSITY   (Japan)

Author keywords

Betel quid chewing; Epithelial dysplasia; p63; Squamous cell carcinoma; Submucous fibrosis

Indexed keywords

PROTEIN ANTIBODY; PROTEIN P63; TUMOR MARKER;

ADULT; ARTICLE; BASAL CELL; BETEL NUT; BETEL QUID; CELL NUCLEUS; CLINICAL ARTICLE; DYSPLASIA; FIBROSIS; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MASTICATION; MOUTH CANCER; MOUTH CARCINOMA; ORAL MUCOSAL DISEASE; PRECANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; SRI LANKA; STATISTICAL SIGNIFICANCE;

ADULT; ARECA; DNA-BINDING PROTEINS; EPITHELIUM; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; MASTICATION; MIDDLE AGED; MOUTH MUCOSA; MOUTH NEOPLASMS; ORAL SUBMUCOUS FIBROSIS; SRI LANKA; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEINS;

EID: 37249036665     PISSN: 18601480     EISSN: 18601499     Source Type: Journal    
DOI: 10.1007/s00795-007-0383-6     Document Type: Article

References (31)

1. JJ Pindborg 1980 Oral cancer and precancer Eright Bristol
2. I Chiba M Muthumala Y Yamazaki A Uz Zaman T Iizuka A Amemiya T Shibata H Kashiwazaki C Sugiura H Fukuda 1998 Characteristics of mutations in the p53 gene of oral squamous-cell carcinomas associated with betel-quid chewing in Sri lanka J Cancer 77 839 842
3. E Brambilla C Brambilla 1997 p53 and lung cancer Pathol Biol 45 852 863
4. K Nylander E Dabelsteen PA Hall 2000 The p53 molecule and its prognostic role in squamous cell carcinoma of the head and neck J Oral Pathol Med 29 413 425
5. AJ Levine 1997 p53, the cellular gatekeeper for growth and division Cell 88 323 331
6. C Prives PA Hall 1999 The p53 pathway J Pathol 187 112 126
7. CA Finlay PW Hids TH Tan D Eliyahu M Oren AJ Levine 1998 Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life Mol Cell Biol 8 531 539
8. M Schmale C Bamberger 1997 A novel protein with strong homology to the tumor suppressor p53 Oncogene 15 1363 1367
9. A Yang M Kaghad Y Wang E Gillett MD Fleming V Dotsch NC Andrews D Caput F McKeon 1998 p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities Mol Cell 2 305 316
10. H Choi JG Batsakis F Zhan E Sturgis MA Luna AK El-Naggar 2002 Differential expression of p53 gene family members p63 and p73 in head and neck squamous tumorigenesis Hum Pathol 33 158 164
11. MP Foschini Gaiba R Cocchi MG Pennesi MR Gatto GP Frezza A Pession 2004 Pattern of p63 expression in squamous cell carcinoma of the oral cavity Virchows Arch 444 332 339
12. C DoComo JU Marshall I Babayan M Drobnyak CV Hedvat J Teruya-Feldstein K Pohar A Hoos C Cordon-Cardo 2002 p63 expression profiles in human normal and tumor tissues Clin Cancer Res 8 494 501
13. YK Chen SS Huse LM Lin 2003 Differential expression of p53, p63 and p73 proteins in human buccal squamous cell carcinomas Clin Otolaryngol 28 451 455
14. YK Chen SS Hsue LM Lin 2004 Expression of p63 (TA and ΔN isoforms) in human primary well differentiated buccal carcinoma Int J Oral Maxillofac Surg 33 493 497
15. Y Chen SS Huse LM Lin 2004 Differential expression of p53, p63 and p73 protein and mRNA for DMBA-induced hamster buccal-pouch squamous-cell carcinoma J Exp Pathol 85 97 104
16. N Thurfjell PJ Coates T Uusitalo D Mahani E Dabelsteen A Dahlqvist B Sjostrom G Roos K Nylander 2004 Complex p63 mRNA isoform expression patterns in squamous cell carcinoma of the head and neck J Oncol 25 27 35
17. G Pelosi F Pasini C Olsen Stenholm U Pastorino P Maisonneuve A Sonzogni F Maffini G Prueri F Fraggetta A Cavallon E Roz A Iannucci E Bresaola G Viale 2003 p63 immunoreactivity in lung cancer: yet another player in the development of squamous cell carcinoma? J Pathol 198 100 109
18. BY Wang J Gil D Kaufman L Gan DS Khots DE Burstain 2002 p63 in pulmonary epithelium, pulmonary squamous neoplasm, and other pulmonary tumors Hum Pathol 33 921 926
19. M Wu B Wang J Gil E Sabo I Miller L Gan DE Burstein 2003 p63 and TTF-1 immunostaining. A useful marker panel for distinguishing small cell carcinoma of the lung from poorly differentiated squamous cell carcinoma of the lung Am J Clin Pathol 19 696 702
20. JA Regezi E Regev S Pisanty S Silverman D Gazit 1995 p53 expression in sequential oral dysplasias and in situ carcinomas J Oral Pathol Med 24 18 22
21. K Yokoo H Noma T Inoue S Hashimoto M Shimono 2004 Cell proliferation and tumour suppressor gene expression in iodine unstained area surrounding oral squamous cell carcinoma Int J Oral Maxillofac Surg 33 75 83
22. SA Shahnavaz JA Regezi G Bradley ID Dube RCK Jordan 2000 p53 gene mutations in sequential oral epithelial dysplasias and squamous cell carcinomas J Pathol 190 417 422
23. MC Bortoluzzi LS Yurgel NP Dekker RCK Jordan JA Regezi 2004 Assesment of p63 expression in oral squamous cell carcinomas and dysplasia Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98 698 704
24. Y-K Chen S-S Hsue L-M Lin 2005 Expression of p63 protein and mRNA in oral epithelial dysplasia J Oral Pathol Med 34 232 239
25. T Takeda K Sugihara Y Hirayama M Hirano J-I Tanuma I Semba 2006 Immunohistological evaluation of Ki-67, p63, CK19 and p53 expression in oral epithelial dysplasia J Oral Pathol Med 35 369 375
26. D-H Sheih L-C Chiang C-H Lee Y-H Yang T-Y Sheih 2004 Effect of arecoline, safrole, and nicotine on collagen phagocytosis by human buccal mucosal fibroblasts as a possible mechanism for oral submucous fibrosis in Taiwan J Oral Pathol Med 33 581 587
27. U Wollina S Verma A Parikh D Parikh 2004 Oral disease caused by the chewing of betel nut and concoctions containing betel nut Eur Acad Dermatol Venereol 18 221 242
28. JA Regezi JJ Scuibba 1999 White lesions JA Regezi JJ Scuibba Oral pathology: clinical pathologic correlations 3rd edn Saunders Philadelphia 83 121
29. BSC Cox DM Walker 1996 Epithelial growth fraction and expression of p53 tumour suppressor gene in oral submucous fibrosis Aust Dent J 41 294 299
30. C Trivedy KA Warnakulasuriya M Tavassoli H Steingromsdottir J Penhallow R Maher NW Johnson 1998 p53 aberrations in oral submucous fibrosis and oral squamous cell carcinoma detected by immunocytochenmistry and PCR-SSCP J Oral Pathol Med 27 72 77
31. J Kaur N Chakravarti M Mathur A Srivastava R Ralhan 2004 Alterations in expression of retinoid receptor β and p53 in oral submucous fibrosis Oral Dis 10 201 206