Inoculation of Balb/c mice with live attenuated tachyzoites protects against a lethal challenge of Neospora caninum

Parasitology

Volumn 135, Issue 1, 2008, Pages 13-21

  Bartley, P M ^a   Wright, S ^a   Chianini, F ^a   Buxton, D ^a   Innes, E A ^a  

^a MOREDUN RESEARCH INSTITUTE   (United Kingdom)

Author keywords

Attenuated tachyzoites; Neospora caninum; Protective immunity

Indexed keywords

DNA; PARASITE ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN MICROGLIOSIS; BRAIN NECROSIS; CONTROLLED STUDY; CYST; FEMALE; HISTOPATHOLOGY; IMMUNITY; IMMUNOHISTOCHEMISTRY; INOCULATION; MORBIDITY; MORTALITY; MOUSE; NEOSPORA CANINUM; NONHUMAN; PARASITE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TACHYZOITE; TISSUE CULTURE;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; BODY WEIGHT; BRAIN; BRAIN DISEASES; COCCIDIOSIS; DISEASE MODELS, ANIMAL; DNA, PROTOZOAN; DNA, RIBOSOMAL SPACER; FEMALE; IMMUNIZATION; MICE; MICE, INBRED BALB C; NEOSPORA; PROTOZOAN VACCINES; TIME FACTORS; VACCINES, ATTENUATED;

MUS; NEOSPORA; NEOSPORA CANINUM;

EID: 37249024785     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182007003526     Document Type: Article

References (33)

1. Bartley, P. M., Wright, S., Sales, J., Chianini, F., Buxton, D. and Innes, E. A. (2006). Long-term passage of tachyzoites in tissue culture can attenuate virulence of Neospora caninum in vivo. Parasitology 135, 421-432.
2. Baszler, T. V., McElwain, T. F. and Mathison, B. A. (2000). Immunization of BALB/c mice with killed Neospora caninum tachyzoite antigen induces a type 2 immune response and exacerbates encephalitis and neurological disease. Clinical and Diagnostic Laboratory Immunology 7, 893-898.
3. Bjerkas, I., Mohn, S. F. and Presthus, J. (1984). Unidentified cyst-forming sporozoon causing encephalomyelitis and myositis in dogs. Zeitschrift für Parasitenkunde 70, 271-274.
4. Buxton, D., Maley, S. W., Thomson, K. M., Trees, A. J. and Innes, E. A. (1997). Experimental infection of non-pregnant and pregnant sheep with Neospora caninum. Journal of Comparative Pathology 117, 1-16.
5. Buxton, D., Maley, S. W., Wright, S., Thomson, K. M., Rae, A. G. and Innes, E. A. (1998). The pathogenesis of experimental neosporosis in pregnant sheep. Journal of Comparative Pathology 118, 267-279.
6. Cannas, A., Naguleswaran, A., Muller, N., Gottstein, B. and Hemphill, A. (2003). Reduced cerebral infection of Neospora caninum-infected mice after vaccination with recombinant microneme protein NcMIC3 and ribi adjuvant. Journal of Parasitology 89, 44-50.
7. Collantes-Fernandez, E., Zaballos, A., Alvarez-Garcia, G. and Ortega-Mora, L. M. (2002). Quantitative detection of Neospora caninum in bovine aborted fetuses and experimentally infected mice by real-time PCR. Journal of Clinical Microbiology 40, 1194-1198.
8. Conrad, P. A., Sverlow, K., Anderson, M., Rowe, J., BonDurant, R., Tuter, G., Breitmeyer, R., Palmer, C., Thurmond, M. and Ardans, A. (1993). Detection of serum antibody responses in cattle with natural or experimental Neospora infections. Journal of Veterinary Diagnostic Investigation 5, 572-578.
9. Daneshvar, H., Coombs, G. H., Hagan, P. and Phillips, R. S. (2003). Leishmania mexicana and Leishmania major: attenuation of wild-type parasites and vaccination with the attenuated lines. Journal of Infectious Diseases 187, 1662-1668.
10. Dubey, J. P., Buxton, D. and Wouda, W. (2006). Pathogenesis of bovine neosporosis. Journal of Comparative Pathology 134, 267-289.
11. Dubey, J. P., Carpenter, J. L., Speer, C. A., Topper, M. J. and Uggla, A. (1988). Newly recognized fatal protozoan disease of dogs. Journal of the American Veterinary Medical Association 192, 1269-1285.
12. Eperon, S., Bronnimann, K., Hemphill, A. and Gottstein, B. (1999). Susceptibility of B-cell deficient C57BL/6 (microMT) mice to Neospora caninum infection. Parasite Immunology 21, 225-236.
13. Haldorson, G. J., Stanton, J. B., Mathison, B. A., Suarez, C. E. and Baszler, T. V. (2006). Neospora caninum: antibodies directed against tachyzoite surface protein NcSRS2 inhibit parasite attachment and invasion of placental trophoblasts in vitro. Experimental Parasitology 112, 172-178.
14. Holmdahl, O. J. and Mattsson, J. G. (1996). Rapid and sensitive identification of Neospora caninum by in vitro amplification of the internal transcribed spacer 1. Parasitology 112, 177-182.
15. 3H Uracil. Journal of Comparative Pathology 113, 95-100.
16. Innes, E. A., Wright, S., Bartley, P., Maley, S., Macaldowie, C., Esteban-Redondo, I. and Buxton, D. (2005). The host-parasite relationship in bovine neosporosis. Veterinary Immunology and Immunopathology 108, 29-36.
17. Innes, E. A., Wright, S., Maley, S. W., Rae, A. G., Schock, A., Kirvar, E., Bartley, P., Hamilton, C., Carey, I. and Buxton, D. (2001). Protection against vertical transmission in bovine neosporosis. International Journal for Parasitology 31, 1523-1534.
18. Jenkins, M., Parker, C., Tuo, W., Vinyard, B. and Dubey, J. P. (2004). Inclusion of CpG adjuvant with plasmid DNA coding for NcGRA7 improves protection against congenital neosporosis. Infection and Immunity 72, 1817-1819.
19. Kaufmann, H., Yamage, M., Roditi, I., Dobbelaere, D., Dubey, J. P., Holmdahl, O. J., Trees, A. and Gottstein, B. (1996). Discrimination of Neospora caninum from Toxoplasma gondii and other apicomplexan parasites by hybridization and PCR. Molecular and Cellular Probes 10, 289-297.
20. Liddell, S., Parker, C., Vinyard, B., Jenkins, M. and Dubey, J. P. (2003). Immunization of mice with plasmid DNA coding for NcGRA7 or NcsHSP33 confers partial protection against vertical transmission of Neospora caninum. Journal of Parasitology 89, 496-500.
21. Lindsay, D. S. and Dubey, J. P. (1989). Immunohistochemical diagnosis of Neospora caninum in tissue sections. American Journal of Veterinary Research 50, 1981-1983.
22. Lindsay, D. S., Lenz, S. D., Cole, R. A., Dubey, J. P. and Blagburn, B. L. (1995). Mouse model for central nervous system Neospora caninum infections. Journal of Parasitology 81, 313-315.
23. Lindsay, D. S., Lenz, S. D., Blagburn, B. L. and Brake, D. A. (1999). Characterization of temperature-sensitive strains of Neospora caninum in mice. Journal of Parasitology 85, 64-67.
24. Long, M. T., Baszler, T. V. and Mathison, B. A. (1998). Comparison of intracerebral parasite load, lesion development and systemic cytokines in mouse strains infected with Neospora caninum. Journal of Parasitology 84, 316-320.
25. Lundén, A., Wright, S., Allen, J. E. and Buxton, D. (2002). Immunisation of mice against neosporosis. International Journal for Parasitology 32, 867-876.
26. McAllister, M. M., Dubey, J. P., Lindsay, D. S., Jolley, W. R., Wills, R. A. and McGuire, A. M. (1998). Dogs are definitive hosts of Neospora caninum. International Journal for Parasitology 28, 1473-1478.
27. Pinitkiatisakul, S., Mattsson, J. G., Wikman, M., Friedman, M., Bengtsson, K. L., Stahl, S. and Lunden, A. (2005). Immunisation of mice against neosporosis with recombinant NcSRS2 iscoms. Veterinary Parasitology 129, 25-34.
28. Preston, P. M., Jackson, L. A., Sutherland, I. A., Brown, D. J., Schofield, J., Bird, T., Sanderson, A. and Brown, C. G. (2001). Theileria annulata: attenuation of a schizont-infected cell line by prolonged in vitro culture is not caused by the preferential growth of particular host cell types. Experimental Parasitology 98, 188-205.
29. Quinn, H. E., Miller, C. M., Ryce, C., Windsor, P. A. and Ellis, J. T. (2002). Characterization of an outbred pregnant mouse model of Neospora caninum infection. Journal of Parasitology 88, 691-696.
30. Ramamoorthy, S., Lindsay, D. S., Schurig, G. G., Boyle, S. M., Duncan, R. B., Vemulapalli, R. and Sriranganathan, N. (2006). Vaccination with gamma-irradiated Neospora caninum tachyzoites protects mice against acute challenge with N. caninum. Journal of Eukaryotic Microbiology 53, 151-156.
31. Teixeira, L., Marques, A., Meireles, C. S., Seabra, A. R., Rodrigues, D., Madureira, P., Faustino, A. M., Silva, C., Ribeiro, A., Ferreira, P., Correia da Costa, J. M., Canada, N. and Vilanova, M. (2005). Characterization of the B-cell immune response elicited in BALB/c mice challenged with Neospora caninum tachyzoites. Immunology 116, 38-52.
32. Williams, D. J., Guy, C. S., Smith, R. F., Ellis, J., Bjorkman, C., Reichel, M. P. and Trees, A. J. (2007). Immunization of cattle with live tachyzoites of Neospora caninum confers protection against foetal death. Infection and Immunity 75, 1343-1348.
33. Williams, D. J., Guy, C. S., Smith, R. F., Guy, F., McGarry, J. W., McKay, J. S. and Trees, A. J. (2003). First demonstration of protective immunity against foetopathy in cattle with latent Neospora caninum infection. International Journal for Parasitology 33, 1059-1065.