Trichosanthes kirilowii tuber extract induces G2/M phase arrest via inhibition of tubulin polymerization in HepG2 cells

Journal of Ethnopharmacology

Volumn 115, Issue 2, 2008, Pages 209-216

  Shin, Jang Woo ^a   Son, Jin Young ^a   Kang, Jong Koo ^b   Han, Seung Hyun ^c   Cho, Chong Kwan ^a   Son, Chang Gue ^a  

^a Daejeon University   (South Korea)

^b Chungbuk National University   (South Korea)

^c School of Dentistry   (South Korea)

Author keywords

Cell cycle arrest; Cucurbitaceae; Trichosanthes kirilowii; Tubulin polymerization

Indexed keywords

ALPHA TUBULIN; ANTINEOPLASTIC AGENT; BETA TUBULIN; COLCHICINE; FLUOROURACIL; PACLITAXEL; TRICHOSANTHES EXTRACT; TRICHOSANTHES KIRILOWII EXTRACT; TRICHOSANTHIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL GROWTH; CONTROLLED STUDY; DOSE RESPONSE; DRUG DETERMINATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; ENZYME ASSAY; ENZYME RELEASE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LIVER CELL CARCINOMA; MICROTUBULE ASSEMBLY; PLANT TUBER; PROTEIN SYNTHESIS INHIBITION; REAL TIME POLYMERASE CHAIN REACTION; TRICHOSANTHES; TRICHOSANTHES KIRILOWII; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL DIVISION; CELL LINE, TUMOR; COLCHICINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FAR EAST; FLUORESCENT ANTIBODY TECHNIQUE; G2 PHASE; GENE EXPRESSION REGULATION; HUMANS; LIVER NEOPLASMS; MEDICINE, ORIENTAL TRADITIONAL; PACLITAXEL; PLANT EXTRACTS; TIME FACTORS; TRICHOSANTHES; TUBULIN;

CUCURBITACEAE; TRICHOSANTHES KIRILOWII;

EID: 37249005198     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2007.09.030     Document Type: Article

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