Isolation of a putative ribosome inactivating protein from dried roots of Trichosanthes kirilowii used in traditional chinese medicine

Planta Medica

Volumn 70, Issue 4, 2004, Pages 364-365

  Fei, Xu ^a,b,c   Hill, Marco ^b   Ma, Xueyan ^b   Teng, Lirong ^a   Li, Qingshan ^a   Stöckigt, Joachim ^b,d  

^a JILIN UNIVERSITY   (China)

^b Institute of Pharmacy   (Germany)

^c MAX PLANCK INSTITUTE FOR POLYMER RESEARCH   (Germany)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PLANT EXTRACT; RIBOSOME INACTIVATING PROTEIN; TRICHOSANTHES KIRILOWII EXTRACT; UNCLASSIFIED DRUG; VEGETABLE PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CHINESE MEDICINE; CHROMATOGRAPHY; DRUG ISOLATION; MOLECULAR WEIGHT; PLANT; PLANT ROOT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; RIBOSOME; SEQUENCE HOMOLOGY; TRADITIONAL MEDICINE; TRICHOSANTHES KIRILOWII;

AMINO ACID SEQUENCE; DRUGS, CHINESE HERBAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MOLECULAR SEQUENCE DATA; PHYTOTHERAPY; PLANT PROTEINS; PLANT ROOTS; PROTEIN SYNTHESIS INHIBITORS; TRICHOSANTHES;

TRICHOSANTHES; TRICHOSANTHES KIRILOWII;

EID: 2342624507     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-818950     Document Type: Article

References (7)

1. Barbieri L, Battelli MG, Stripe F. Ribosome-inactivating proteins from plants. Biochem Biophys Acta 1993; 1154: 237-82
2. Ding Y, Too H, Wang Z, Liu Y, Bartlam M, Dong Y et al. The structural basis of Trp192 and the C-terminal region in trichosanthin for activity and conformational stability. Protein Engineering. 2003; 16: 351-6
3. Peumans WJ, Hao Q, van Damme EJM. Ribosome-inactivating proteins from plants: more than RNA N-glycosidases? The FASEB Journal 2001; 15: 1493-1506
4. Wang P, Tumer NE. Virus resistance mediated by ribosome inactivating proteins. Adv Virus Res 2000; 55: 325-55
5. + cells by monoclonal antibodies. Nature 1990; 347: 92-5
6. Maraganore JM, Joseph M, Bailey MC Purification and characterization of trichosanthin. Homology to the ricin A chain and implications as to mechanism of abortifacient activity. J Biol Chem 1987; 262: 11628-33
7. Eckerskorn C, Lottspeich F. Internal amino acid sequence analysis of protein separated by gel electrophoresis after tryptic digestion in polyacrylamide matrix. Chromatographia 1989; 28: 92-4