Aminoethyl chitooligosaccharides inhibit the activity of angiotensin converting enzyme

Process Biochemistry

Volumn 43, Issue 1, 2008, Pages 119-123

  Ngo, Dai Nghiep ^a   Qian, Zhong Ji ^a   Je, Jae Young ^b   Kim, Moon Moo ^c   Kim, Se Kwon ^a  

^a Pukyong National University   (South Korea)

^b Chonnam National University   (South Korea)

^c Dong Eui University   (South Korea)

Author keywords

Aminoethyl COS; Angiotensin I converting enzyme (ACE); Chitin; Chitooligosaccharides (COS); Chitosan; Competitive inhibitor

Indexed keywords

CHEMICAL MODIFICATION; CHITIN; DERIVATIVES; ENZYME INHIBITION; GRAFTING (CHEMICAL); MOLECULAR WEIGHT; SUBSTITUTION REACTIONS;

AMINOETHYL COS; ANGIOTENSIN I CONVERTING ENZYME (ACE); CHITOOLIGOSACCHARIDES (COS); CHITOSAN; COMPETITIVE INHIBITORS;

OLIGOSACCHARIDES;

EID: 37149056322     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2007.10.018     Document Type: Article

References (20)

1. Zhang Y., Lee E.T., Devereux R.B., Yeh J., Best L.G., Fabsitz R.R., and Howard B.V. Prehypertension, diabetes, and cardiovascular disease risk in a population based sample: the strong heart study. Hypertension 47 (2006) 410-414
2. Park P.J., Je J.Y., Kim S.K., and Angiotensin. I converting enzyme (ACE) inhibitory activity of hetero-chitooligosaccharides prepared from partially different deacetylated chitosans. J Agric Food Chem 51 (2003) 4930-4934
3. Kuster D.J., and Marshall G.R. Validated ligand mapping of ACE active site. J Comput Aided Mol Des 19 (2005) 609-615
4. Goretta L.A., Ottaviani J.I., and Fraga C.G. Inhibition of Angiotensin converting enzyme activity by Flavanol-rich foods. J Agric Food Chem 54 (2006) 229-234
5. Suetsuna K., and Nakano T. Identification of an antihypertensive peptide from peptic digest of wakame (Undaria pinnatifida). J Nutr Biochem 11 (2000) 450-454
6. Suetsuna K. Identification of antihypertensive peptides from peptic digest of the short-necked clam Tapes philippinarum and the pearl oyster Pinctada fucata martensii. Fisheries Sci 68 (2002) 233-235
7. Kato Y., Onishi H., and Machida Y. Contribution of chitosan and its derivatives to cancer chemotherapy. Rev, In vivo 19 (2005) 301-310
8. Kim S.K., Ngo D.N., and Rajapakse N. Therapeutic prospectives of chitin, chitosan and their derivatives. J Chitin Chitosan 11 1 (2006) 1-10
9. Yang T.C., Chou C.C., and Li C.F. Antibacterial activity of N-alkylated dissaccharide chitosan derivatives. Int J Food Microbiol 97 (2005) 237-245
10. Je J.Y., and Kim S.K. Antimicrobial action of novel chitin derivative. BBA 1760 (2006) 104-109
11. Cusham D.W., and Cheung H.S. Spectrophotometric assay and properties of angiotensin converting enzyme of rabbit lung. Biochem Pharmacol 20 (1971) 1637-1648
12. Maeda Y., and Kimura Y. Antitumor effects of various low molecular weight chitosans are due to increased natural killer activity of intestinal intraepithelial lymphocytes in sarcoma 180-bearing mice. Am Soc Nut Sci 12 (2004) 945-950
13. Redellinghuys P., Nchinda A.T., and Sturrock ED. Development of domain selective angiotensin I converting enzyme inhibitors. Ann NY Acad Sci 1056 (2005) 160-175
14. Hong S.P., Kim M.H., Oh S.W., Han C.K., and Kim Y.H. ACE inhibitory and antihypertensive effect of chitosan oligosaccharides in SHR. Korean J Food Sci Technol 30 (1998) 1476-1479
15. Huang R., Mendis E., and Kim S.K. Improvement of ACE inhibitory activity of chitooligosaccharides (COS) by carboxyl modification. Biorg Med Chem 13 (2005) 3649-3655
16. Je J.Y., Park P.J., Kim B., and Kim S.K. Antihypertensive activity of chitin derivatives. Biopolymer 83 (2006) 250-254
17. Cushman D.W., and Ondetti M.A. Design of angiotensin converting enzyme inhibitors. Nature Med 5 (1999) 1110-1112
18. Cheung H.S., Wang F.L., Ondetti M.A., Sabo E.F., and Cushman DW. Binding of peptide substrate and inhibitors of Angiotensin-converting enzyme. J. Biol Chem 255 (1980) 401-407
19. Michaud A., Williams T.A., Chauvet M.T., and Corvol P. Substrate dependence of Angiotensin I-converting enzyme Inhibition: captopril displays a partial selectivity for inhibition of N-Acetyl-Seryl-Aspartyl-Lysyl-Proline hydrolysis compared with that of Angiotensin I. Mol Pharmacol 51 (1997) 1070-1076
20. Natesh R., Schwager S.L.U., Sturrock E.D., and Acharya K.R. Crystal structure of the human angiotensin-converting enzyme-lisinopril complex. Nature 421 (2003) 551-554