Validated ligand mapping of ACE active site

Journal of Computer-Aided Molecular Design

Volumn 19, Issue 8, 2005, Pages 609-615

  Kuster, Daniel J ^a,b   Marshall, Garland R ^a,b,c  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Active analog; Angiotensin converting enzyme (ACE); Captopril; Constrained systematic search; Enalapril; Lisinopril; Ramipril

Indexed keywords

ENZYMES; LIGANDS; MAPPING;

ACTIVE ANALOG; ANGIOTENSIN-CONVERTING ENZYME; CAPTOPRIL; CONSTRAINED SYSTEMATIC SEARCH; ENALAPRIL; ENZYME ACTIVE SITES; LISINOPRIL; RAMIPRIL; SYSTEMATIC SEARCHES;

CONFORMATIONS;

BENAZEPRIL; CAPTOPRIL; CILAZAPRIL; DIPEPTIDYL CARBOXYPEPTIDASE; ENALAPRIL; ENALAPRIL MALEATE; FOSINOPRIL; LISINOPRIL; OMAPATRILAT; PERINDOPRIL; QUINAPRIL; RAMIPRIL; TRANDOLAPRIL;

ACCURACY; ARTICLE; COMPUTER ANALYSIS; COMPUTER PROGRAM; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG POTENCY; DRUG RESEARCH; DRUG STRUCTURE; ENZYME STRUCTURE; GENE MAPPING; GEOMETRY; METHODOLOGY; PHARMACOPHORE; PREDICTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING; VALIDATION PROCESS;

EID: 31444453419     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-005-9017-z     Document Type: Article

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