Cardioprotective effects of propofol and midazolam in children with congenital heart diseases undergoing open heart surgery

National Medical Journal of China

Volumn 87, Issue 33, 2007, Pages 2309-2312

  Zou, Han Dong ^a   Zhou, Qing Shan ^a   Xia, Wen Fang ^a   Wu, Ling Xi ^a   Cheng, Bang Chang ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Anesthetics; Cardiac troponin I; Heart defects, congenital

Indexed keywords

FENTANYL; HEME OXYGENASE 1; MIDAZOLAM; OXYGEN; PROPOFOL; TROPONIN I;

ADOLESCENT; AORTA CLAMPING; ARTICLE; BLOOD OXYGEN TENSION; BLOOD SAMPLING; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYANOTIC HEART DISEASE; ELECTROCARDIOGRAPHY; EXTUBATION; HEART HEMODYNAMICS; HEART MUSCLE BIOPSY; HEART MUSCLE CELL; HEART PROTECTION; HOSPITALIZATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTENSIVE CARE UNIT; LOW DRUG DOSE; MEDICAL RECORD; NASOPHARYNX; OPEN HEART SURGERY; PATIENT MONITORING; PEDIATRIC CARDIOLOGY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RECTUM TEMPERATURE; STATISTICAL SIGNIFICANCE; TIME; VENOUS BLOOD;

ADOLESCENT; ANESTHETICS, INTRAVENOUS; BODY TEMPERATURE; CARDIAC SURGICAL PROCEDURES; CARDIOTONIC AGENTS; CHILD; CHILD, PRESCHOOL; ELECTROCARDIOGRAPHY; EXTRACORPOREAL CIRCULATION; HEART DEFECTS, CONGENITAL; HEME OXYGENASE-1; HUMANS; MIDAZOLAM; PROPOFOL; TROPONIN I;

EID: 37149028405     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Culza G, Lerzo F, Perfum F, et al. Clinical evaluation of oxidative stress and myocardial reperfusion injury in pediatric cardiac surgery. J Cardiovasc Surg, 2002, 43:441-443.
2. Jaradov SA, Lim KH, Kerr PM, et al. Protection of hearts from reperfusion injury by propofol is associated with inhibition of the mitochondrial permeability transition. Cardiovasc Res, 2000, 45: 360-369.
3. Rigby-Jones AE, Nolan TA, Priston MJ, et al. Pharmocokinetics of propofol in critically ill neonates, infants, and children in an intensive care unit. Anesthesiology, 2002, 97:1393-1400.
4. 2 consumption and lactate production during ischemia in dogs. J Cardiothorac Vasc Anesth, 1994, 8:302-309.
5. Gunther W, Andreas B, Siegmund B, et al. No difference in postoperative cardiac troponin T between a sevoflurane or midazolam-supplemented opioid anesthetic in patients undergoing on-pump coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth, 2007,21:162-164.
6. Chinese source.
7. Chinese source.
8. Chinese source.
9. Malagon I, Hogenbirk K, Van Pelt J, et al. Effect of three different anaesthetic agents on the postoperative production of cardiac troponin T in paediatric cardiac surgery. Br J Anesth, 2005,94:805-809.
10. Yet SF, Tian R, Layne MD, et al. Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice. Cire Res, 2001, 89:168-173.
11. Yet SF, Lin Y, Anrather J, et al. Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice. J Clin Invest, 1999, 103:R23-29.
12. Shan Y, Pepe J, Lambrecht RW, et al. Mapping of the chick heme oxygenase-1 proximal promoter for responsiveness to metalloporphyrins. Arch Biochem Biophys, 2002, 399:159-166.
13. Carden DL, Granger DN. Pathophysiology of ischemia-reperfusion injury. Am J Pathol, 2000, 190:255-266.
14. Otterbein LE , Choi AM. Heme oxygenase: colors of defense against cellular stress. Am J Physiol Lung Cell Mol Physiol, 2000, 279:1029-1037.
15. Weber TP, Meissner A, Boknik P, et al. Hemin, inducer of heme-oxygenase 1, improves functional recovery from myocardial stunning in conscious dogs. J Cardiothorac Vasc Anesth, 2001, 15:422-427.
16. De Hert SG, Van der Linden PJ, Cromheecke S, et al. Choice of primary anesthetic regimen can influence intensive care unit length of stay after coronary surgery with cardiopulmonary bypass. Anesthesiology, 2004, 101:9-20.