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Volumn 70, Issue 1, 2008, Pages 229-234

Transient Genome-Wide Transcriptional Response to Low-Dose Ionizing Radiation In Vivo in Humans

Author keywords

Biosignature; Genomic expression patterns; Human; In vivo dosimetry; Low dose ionizing radiation

Indexed keywords

DNA; DOSIMETRY; IONIZING RADIATION; PATIENT MONITORING; SKIN; TISSUE;

EID: 37049021112     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2007.09.026     Document Type: Article
Times cited : (43)

References (34)
  • 1
    • 0023272104 scopus 로고
    • Is the rate of repair of radiation-induced sublethal damage in rat spinal cord dependent on the size of dose per fraction?
    • Ang K.K., Thames Jr. H.D., van der Kogel A.J., et al. Is the rate of repair of radiation-induced sublethal damage in rat spinal cord dependent on the size of dose per fraction?. Int J Radiat Oncol Biol Phys 13 (1987) 557-562
    • (1987) Int J Radiat Oncol Biol Phys , vol.13 , pp. 557-562
    • Ang, K.K.1    Thames Jr., H.D.2    van der Kogel, A.J.3
  • 2
  • 3
    • 7244239293 scopus 로고    scopus 로고
    • Mechanisms of radiation injury to the central nervous system: Implications for neuroprotection
    • Wong C.S., and Van der Kogel A.J. Mechanisms of radiation injury to the central nervous system: Implications for neuroprotection. Mol Interv 4 (2004) 273-284
    • (2004) Mol Interv , vol.4 , pp. 273-284
    • Wong, C.S.1    Van der Kogel, A.J.2
  • 4
    • 31444436762 scopus 로고    scopus 로고
    • Dosimetry for quantitative analysis of the effects of low-dose ionizing radiation in radiation therapy patients
    • Lehmann J., Stern R.L., Daly T.P., et al. Dosimetry for quantitative analysis of the effects of low-dose ionizing radiation in radiation therapy patients. Radiat Res 165 (2006) 240-247
    • (2006) Radiat Res , vol.165 , pp. 240-247
    • Lehmann, J.1    Stern, R.L.2    Daly, T.P.3
  • 5
    • 33846185085 scopus 로고    scopus 로고
    • Optimized methodology for sequential extraction of RNA and protein from small human skin biopsies
    • Berglund S.R., Schwietert C.W., Jones A.A., et al. Optimized methodology for sequential extraction of RNA and protein from small human skin biopsies. J Invest Dermatol 127 (2007) 349-353
    • (2007) J Invest Dermatol , vol.127 , pp. 349-353
    • Berglund, S.R.1    Schwietert, C.W.2    Jones, A.A.3
  • 6
    • 0032878399 scopus 로고    scopus 로고
    • Induction of stress genes by low doses of gamma rays
    • Amundson S.A., Do K.T., and Fornace Jr. A.J. Induction of stress genes by low doses of gamma rays. Radiat Res 152 (1999) 225-231
    • (1999) Radiat Res , vol.152 , pp. 225-231
    • Amundson, S.A.1    Do, K.T.2    Fornace Jr., A.J.3
  • 7
    • 0037392144 scopus 로고    scopus 로고
    • Differential responses of stress genes to low dose-rate gamma irradiation
    • Amundson S.A., Lee R.A., Koch-Paiz C.A., et al. Differential responses of stress genes to low dose-rate gamma irradiation. Mol Cancer Res 1 (2003) 445-452
    • (2003) Mol Cancer Res , vol.1 , pp. 445-452
    • Amundson, S.A.1    Lee, R.A.2    Koch-Paiz, C.A.3
  • 8
    • 21244456450 scopus 로고    scopus 로고
    • Gene expression profiles of normal human fibroblasts after exposure to ionizing radiation: A comparative study of low and high doses
    • Ding L.H., Shingyoji M., Chen F., et al. Gene expression profiles of normal human fibroblasts after exposure to ionizing radiation: A comparative study of low and high doses. Radiat Res 164 (2005) 17-26
    • (2005) Radiat Res , vol.164 , pp. 17-26
    • Ding, L.H.1    Shingyoji, M.2    Chen, F.3
  • 9
    • 0036179945 scopus 로고    scopus 로고
    • Stress-gene induction by low-dose gamma irradiation
    • Fornace Jr. A.J., Amundson S.A., Do K.T., et al. Stress-gene induction by low-dose gamma irradiation. Mil Med 167 (2002) 13-15
    • (2002) Mil Med , vol.167 , pp. 13-15
    • Fornace Jr., A.J.1    Amundson, S.A.2    Do, K.T.3
  • 10
    • 19544378138 scopus 로고    scopus 로고
    • Low-dose exposure to gamma rays induces specific gene regulations in normal human keratinocytes
    • Franco N., Lamartine J., Frouin V., et al. Low-dose exposure to gamma rays induces specific gene regulations in normal human keratinocytes. Radiat Res 163 (2005) 623-635
    • (2005) Radiat Res , vol.163 , pp. 623-635
    • Franco, N.1    Lamartine, J.2    Frouin, V.3
  • 11
    • 33750065724 scopus 로고    scopus 로고
    • Effects of low-dose gamma radiation on DNA damage, chromosomal aberration and expression of repair genes in human blood cells
    • Sudprasert W., Navasumrit P., and Ruchirawat M. Effects of low-dose gamma radiation on DNA damage, chromosomal aberration and expression of repair genes in human blood cells. Int J Hyg Environ Health 209 (2006) 503-511
    • (2006) Int J Hyg Environ Health , vol.209 , pp. 503-511
    • Sudprasert, W.1    Navasumrit, P.2    Ruchirawat, M.3
  • 12
    • 0344121661 scopus 로고    scopus 로고
    • Gene expression changes in mouse brain after exposure to low-dose ionizing radiation
    • Yin E., Nelson D.O., Coleman M.A., et al. Gene expression changes in mouse brain after exposure to low-dose ionizing radiation. Int J Radiat Biol 79 (2003) 759-775
    • (2003) Int J Radiat Biol , vol.79 , pp. 759-775
    • Yin, E.1    Nelson, D.O.2    Coleman, M.A.3
  • 14
    • 0034231548 scopus 로고    scopus 로고
    • Radiation Therapy Oncology Group (RTOG) trials for head and neck cancer
    • Cox J.D., Fu K.K., Pajak T.F., et al. Radiation Therapy Oncology Group (RTOG) trials for head and neck cancer. Rays 25 (2000) 321-323
    • (2000) Rays , vol.25 , pp. 321-323
    • Cox, J.D.1    Fu, K.K.2    Pajak, T.F.3
  • 15
    • 26844505738 scopus 로고    scopus 로고
    • Hospital management of mass radiological casualties: Reassessing exposures from contaminated victims of an exploded radiological dispersal device
    • Smith J.M., Ansari A., and Harper F.T. Hospital management of mass radiological casualties: Reassessing exposures from contaminated victims of an exploded radiological dispersal device. Health Phys 89 (2005) 513-520
    • (2005) Health Phys , vol.89 , pp. 513-520
    • Smith, J.M.1    Ansari, A.2    Harper, F.T.3
  • 16
    • 0041467243 scopus 로고    scopus 로고
    • Radiological terrorism
    • quiz 22-14
    • Timins J.K., and Lipoti J.A. Radiological terrorism. N J Med 100 (2003) 14-21 quiz 22-14
    • (2003) N J Med , vol.100 , pp. 14-21
    • Timins, J.K.1    Lipoti, J.A.2
  • 17
    • 84928096192 scopus 로고    scopus 로고
    • Radiological and nuclear terrorism: Are you prepared?
    • Van Moore Jr. A. Radiological and nuclear terrorism: Are you prepared?. J Am Coll Radiol 1 (2004) 54-58
    • (2004) J Am Coll Radiol , vol.1 , pp. 54-58
    • Van Moore Jr., A.1
  • 18
    • 33745683515 scopus 로고    scopus 로고
    • Human in vivo dose-response to controlled, low-dose low linear energy transfer ionizing radiation exposure
    • Goldberg Z., Rocke D.M., Schwietert C., et al. Human in vivo dose-response to controlled, low-dose low linear energy transfer ionizing radiation exposure. Clin Cancer Res 12 (2006) 3723-3729
    • (2006) Clin Cancer Res , vol.12 , pp. 3723-3729
    • Goldberg, Z.1    Rocke, D.M.2    Schwietert, C.3
  • 19
    • 9244226546 scopus 로고    scopus 로고
    • Design and analysis of experiments with high throughput biological assay data
    • Rocke D.M. Design and analysis of experiments with high throughput biological assay data. Sem Cell Dev Biol 15 (2004) 708-713
    • (2004) Sem Cell Dev Biol , vol.15 , pp. 708-713
    • Rocke, D.M.1
  • 20
    • 27744446046 scopus 로고    scopus 로고
    • A method for detection of differential gene expression in the presence of inter-individual variability in response
    • Rocke D.M., Goldberg Z., Schweitert C., et al. A method for detection of differential gene expression in the presence of inter-individual variability in response. Bioinformatics 21 (2005) 3990-3992
    • (2005) Bioinformatics , vol.21 , pp. 3990-3992
    • Rocke, D.M.1    Goldberg, Z.2    Schweitert, C.3
  • 21
    • 0037335568 scopus 로고    scopus 로고
    • Stress and radiation-induced activation of multiple intracellular signaling pathways
    • Dent P., Yacoub A., Contessa J., et al. Stress and radiation-induced activation of multiple intracellular signaling pathways. Radiat Res 159 (2003) 283-300
    • (2003) Radiat Res , vol.159 , pp. 283-300
    • Dent, P.1    Yacoub, A.2    Contessa, J.3
  • 22
    • 5644271454 scopus 로고    scopus 로고
    • p38 MAPK mediates gamma-irradiation-induced endothelial cell apoptosis, and vascular endothelial growth factor protects endothelial cells through the phosphoinositide 3-kinase-Akt-Bcl-2 pathway
    • Kumar P., Miller A.I., and Polverini P.J. p38 MAPK mediates gamma-irradiation-induced endothelial cell apoptosis, and vascular endothelial growth factor protects endothelial cells through the phosphoinositide 3-kinase-Akt-Bcl-2 pathway. J Biol Chem 279 (2004) 43352-43360
    • (2004) J Biol Chem , vol.279 , pp. 43352-43360
    • Kumar, P.1    Miller, A.I.2    Polverini, P.J.3
  • 23
    • 3042628086 scopus 로고    scopus 로고
    • Basic fibroblast growth factor inhibits radiation-induced apoptosis of HUVECs. II. The RAS/MAPK pathway and phosphorylation of BAD at serine 112
    • Gu Q., Wang D., Wang X., et al. Basic fibroblast growth factor inhibits radiation-induced apoptosis of HUVECs. II. The RAS/MAPK pathway and phosphorylation of BAD at serine 112. Radiat Res 161 (2004) 703-711
    • (2004) Radiat Res , vol.161 , pp. 703-711
    • Gu, Q.1    Wang, D.2    Wang, X.3
  • 24
    • 20444492764 scopus 로고    scopus 로고
    • Mechanisms of disease: Radiosensitization by epidermal growth factor receptor inhibitors
    • Sartor C. Mechanisms of disease: Radiosensitization by epidermal growth factor receptor inhibitors. Nat Clin Pract Oncol 1 (2004) 22-30
    • (2004) Nat Clin Pract Oncol , vol.1 , pp. 22-30
    • Sartor, C.1
  • 25
    • 0032484194 scopus 로고    scopus 로고
    • Impaired ionizing radiation-induced activation of a nuclear signal essential for phosphorylation of c-Jun by dually phosphorylated c-Jun amino-terminal kinases in ataxia telangiectasia fibroblasts
    • Lee S.A., Dritschilo A., and Jung M. Impaired ionizing radiation-induced activation of a nuclear signal essential for phosphorylation of c-Jun by dually phosphorylated c-Jun amino-terminal kinases in ataxia telangiectasia fibroblasts. J Biol Chem 273 (1998) 32889-32894
    • (1998) J Biol Chem , vol.273 , pp. 32889-32894
    • Lee, S.A.1    Dritschilo, A.2    Jung, M.3
  • 26
    • 0037382977 scopus 로고    scopus 로고
    • Dose-dependent differential expression of protein kinase C isozymes in mouse lymphocytes after gamma irradiation in vivo and ex vivo
    • Varadkar P.A., Krishna M., and Verma N.C. Dose-dependent differential expression of protein kinase C isozymes in mouse lymphocytes after gamma irradiation in vivo and ex vivo. Radiat Res 159 (2003) 453-457
    • (2003) Radiat Res , vol.159 , pp. 453-457
    • Varadkar, P.A.1    Krishna, M.2    Verma, N.C.3
  • 27
    • 3042713048 scopus 로고    scopus 로고
    • Transforming growth factor-beta is an endogenous radioresistance factor in the esophageal adenocarcinoma cell line OE-33
    • Kim A.H., Lebman D.A., Dietz C.M., et al. Transforming growth factor-beta is an endogenous radioresistance factor in the esophageal adenocarcinoma cell line OE-33. Int J Oncol 23 (2003) 1593-1599
    • (2003) Int J Oncol , vol.23 , pp. 1593-1599
    • Kim, A.H.1    Lebman, D.A.2    Dietz, C.M.3
  • 28
    • 1542356004 scopus 로고    scopus 로고
    • Ionizing radiation up-regulates cyclooxygenase-2 in I407 cells through p38 mitogen-activated protein kinase
    • Tessner T.G., Muhale F., Schloemann S., et al. Ionizing radiation up-regulates cyclooxygenase-2 in I407 cells through p38 mitogen-activated protein kinase. Carcinogenesis 25 (2004) 37-45
    • (2004) Carcinogenesis , vol.25 , pp. 37-45
    • Tessner, T.G.1    Muhale, F.2    Schloemann, S.3
  • 29
    • 0031792592 scopus 로고    scopus 로고
    • Variability of individual normal tissue radiation sensitivity. An international empirical evaluation of endogenous and exogenous response modifiers
    • Zimmermann J.S., Kumpf L., and Kimmig B. Variability of individual normal tissue radiation sensitivity. An international empirical evaluation of endogenous and exogenous response modifiers. Strahlenther Onkol 174 Suppl 3 (1998) 16-19
    • (1998) Strahlenther Onkol , vol.174 , Issue.SUPPL. 3 , pp. 16-19
    • Zimmermann, J.S.1    Kumpf, L.2    Kimmig, B.3
  • 30
    • 1542514781 scopus 로고    scopus 로고
    • Regulation of radiation-induced apoptosis by early growth response-1 gene in solid tumors
    • Ahmed M.M. Regulation of radiation-induced apoptosis by early growth response-1 gene in solid tumors. Curr Cancer Drug Targets 4 (2004) 43-52
    • (2004) Curr Cancer Drug Targets , vol.4 , pp. 43-52
    • Ahmed, M.M.1
  • 31
    • 0034878548 scopus 로고    scopus 로고
    • The Trp53 pathway is induced in vivo by low doses of gamma radiation
    • MacCallum D.E., Hall P.A., and Wright E.G. The Trp53 pathway is induced in vivo by low doses of gamma radiation. Radiat Res 156 (2001) 324-327
    • (2001) Radiat Res , vol.156 , pp. 324-327
    • MacCallum, D.E.1    Hall, P.A.2    Wright, E.G.3
  • 32
    • 0032573165 scopus 로고    scopus 로고
    • Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms
    • Li N., and Karin M. Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms. Proc Natl Acad Sci U S A 95 (1998) 13012-13017
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 13012-13017
    • Li, N.1    Karin, M.2
  • 33
    • 0035337151 scopus 로고    scopus 로고
    • Ionizing radiation affects 26s proteasome function and associated molecular responses, even at low doses
    • Pajonk F., and McBride W.H. Ionizing radiation affects 26s proteasome function and associated molecular responses, even at low doses. Radiother Oncol 59 (2001) 203-212
    • (2001) Radiother Oncol , vol.59 , pp. 203-212
    • Pajonk, F.1    McBride, W.H.2
  • 34
    • 27744579507 scopus 로고    scopus 로고
    • An expression index for Affymetrix GeneChips based on the generalized logarithm
    • Zhou L., and Rocke D.M. An expression index for Affymetrix GeneChips based on the generalized logarithm. Bioinformatics 21 (2005) 3983-3989
    • (2005) Bioinformatics , vol.21 , pp. 3983-3989
    • Zhou, L.1    Rocke, D.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.