A method for detection of differential gene expression in the presence of inter-individual variability in response

Bioinformatics

Volumn 21, Issue 21, 2005, Pages 3990-3992

  Rocke, David M ^a   Goldberg, Zelanna ^b   Schweitert, Chad ^b   Santana, Alison ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOINFORMATICS; CLINICAL ARTICLE; COMPUTER SYSTEM; DNA MICROARRAY; DOSE RESPONSE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; INFORMATION RETRIEVAL; INTERMETHOD COMPARISON; MATHEMATICAL COMPUTING; OBSERVER VARIATION; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE; RADIATION EXPOSURE; RANK SUM TEST; SKIN BIOPSY; STATISTICAL MODEL; STATISTICS; STUDENT T TEST;

EID: 27744446046     PISSN: 13674803     EISSN: 13674811     Source Type: Journal    
DOI: 10.1093/bioinformatics/bti667     Document Type: Article

References (7)

1. Benjamini,Y. and Hochberg,Y. (1995) Controlling the false discovery rate. J. R. Stat. Soc. Ser. B, 57, 289-300.
2. Chomczynski,P. and Sacchi,N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate phenol-chloroform extraction. Anal Biochem., 162, 156-159.
3. Goldberg et al. (2005) In vivo transcriptional response in humans to controlled, low - dose ionizing radiation exposure. In press
4. Irizarry,R.A. et al. (2003) Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res. Methods Online, 31, e15.
5. Reiner,A. et al. (2003) Identifying differentially expressed genes using false discovery rate controlling procedures. Bioinformatics, 19, 368-375.
6. Rocke,D.M. (2004) Design and analysis of experiments with high throughput biological assay data. Sem. Cell Dev. Biol., 15, 708-713.
7. Zhou,L. and Rocke,D.M. (2005) An expression index for Affymetrix GeneChips based on the generalized logarithm. Bioinformatics, 21, 3983-3989.