Exposure-triggered reproductive toxicity testing under the REACH legislation: A proposal to define significant/relevant exposure

Toxicology Letters

Volumn 176, Issue 1, 2008, Pages 68-76

  Bernauer, Ulrike ^a   Heinemeyer, Gerhard ^a   Heinrich Hirsch, Barbara ^a   Ulbrich, Beate ^a   Gundert Remy, Ursula ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

Author keywords

Exposure based waiving; REACH; Reproductive toxicity; Threshold of toxicological concern (TTC)

Indexed keywords

ORGANOPHOSPHATE;

ARTICLE; DATA BASE; DECISION TREE; ENVIRONMENTAL EXPOSURE; EUROPE; FERTILITY; FETOTOXICITY; FOOD SAFETY; GENOTOXICITY; HEALTH HAZARD; HUMAN; INGESTION; INHALATION; LAW; NONHUMAN; OUTCOME ASSESSMENT; PRENATAL EXPOSURE; PRIORITY JOURNAL; REPRODUCTION; REPRODUCTIVE TOXICITY; RISK ASSESSMENT; TARGET ORGAN; TOXICITY TESTING; TOXICOKINETICS;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; FEASIBILITY STUDIES; FERTILITY; GROWTH AND DEVELOPMENT; GUIDELINES AS TOPIC; HUMANS; OCCUPATIONAL EXPOSURE; REPRODUCTION; RISK ASSESSMENT; TERMINOLOGY AS TOPIC; TOXICITY TESTS; TOXICOLOGY;

EID: 37049008719     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2007.10.008     Document Type: Article

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