A scalable process for the synthesis of the Bcl inhibitor obatoclax

Organic Process Research and Development

Volumn 11, Issue 6, 2007, Pages 1051-1054

  Daïri, Kenza ^a   Yao, Yuxing ^b   Faley, Michael ^b   Tripathy, Sasmita ^a   Rioux, Elise ^a   Billot, Xavier ^a   Rabouin, Daniel ^a   Gonzalez, Gerson ^a   Lavallée, Jean François ^a   Attardo, Giorgio ^a  

^a INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^b SAFC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 37049005799     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op7001613     Document Type: Article

References (20)

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20. The process no longer requires the use of NaH, diethyl ether, or pentane as described in the Experimental Section. 1-(N-Methoxycarbonyl)indole-2- boronic acid is now commercially available from SAFC.